Subunit composition of the pre-T-cell receptor complex analysed by monoclonal antibody against the pre-T-cell receptor α chain

Immunology

Volumn 91, Issue 4, 1997, Pages 618-622

  Kosugi, A ^a,b   Noda, S ^b   Saitoh, S I ^b   Narumiya, S ^b   Ogata, M ^b   Hashimoto, Y ^c   Takase, K ^d   Saito, T ^d   Hamaoka, T ^b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c Syntex Roche Institute of Immunology   (Japan)

^d CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINE; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0030759762     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00294.x     Document Type: Article

References (25)

1. GROETTRUP M. & VON BOEHMER H. (1993) A role for a pre-T-cell receptor in T-cell development. Immunol Today 14, 610.
2. LEVELT C.N. & EICHMANN K. (1995) Receptors and signals in early thymic selection. Immunity 3, 667.
3. TANAKA Y., ARDOUIN L., GILLET A, et al. (1995) Early T-cell development in CD3-deficient mice. Immunol Rev 148, 171.
4. SAINT-RUF C., UNGEWISS K., GROETTRUP M., BRUNO L., FEHLING H.J. & VON BOEHMER H. (1994) Analysis and expression of a cloned pre-T cell receptor gene. Science 266, 1208.
5. DEL PORTO P., BRUNO L., MATTEI M.-G., VON BOEHMER H. & SAINT-RUF C. (1995) Cloning and comparative analysis of the human pre-T-cell receptor α-chain gene. Proc Natl Acad Sci USA 92, 12 105.
6. MOMBAERTS P., CLARKE A.R., RUDNICKI M.A. et al. (1992) Mutations in T-cell antigen receptor genes α and β block thymocyle development at different stages. Nature 360, 225.
7. FEHLING H.J., KROTKOVA A., SAINT-RUF C. & VON BOEHMER H. (1995) Crucial role of the pre-T-cell receptor a gene in development of αβ but not γδ T cells. Nature 375, 795.
8. GROETTRUP M., BARON A., GRIFFITHS G., PALACIOS R. & VON BOEHMER H. (1992) T cell receptor (TCR) β chain homodimers on the surface of immature but not mature α, γ, δ chain deficient T cell lines. EMBO J 11, 2735.
9. PUNT J.A., KUBO R.T., SAITO T. et al. (1991) Surface expression of a T cell receptor β (TCR-β) chain in the absence of TCR-α, -δ, and -γ proteins. J Exp Med 174, 775.
10. - mice in the absence of TCRβ chain expression. Int Immunol 7, 995.
11. JACOBS H., VANDEPUTTE D., TOLKAMP L., DE VRIES E., BORST J. & BERNS A. (1994) CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo. Eur J Immunol 24, 934.
12. KUWABARA K., OHNO H., PUNT J.A., HASHIMOTO Y. & SAITO T. (1994) Transition from TCR-β dimer to TCR-αβ-expressing cells by introduction of an α-chain in an immature thymocyte cell line. J Immunol 152, 2148.
13. VAN OERS N.S.C., VON BOEHMER H. & WEISS A. (1995) The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit. J Exp Med 182, 1585.
14. OGATA M., SAWADA M., FUJINO Y. & HAMAOKA T. (1995) cDNA cloning and characterization of a novel receptor-type tyrosine phosphatase predominantly expressed in the brain. J Biol Chem 250, 2337.
15. KUBO R.T., BORN W., KAPPLER J.W., MARRACK P. & PIGEON M. (1989) Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J Immunol 142, 2736.
16. BORN W., MILES C., WHITE J. et al. (1987) Peptide sequences of T cell receptor δ and γ chains are identical to predicted X and γ proteins. Nature 330, 572.
17. SAMELSON L.E., GERMAIN R.N. & SCHWARTZ R.H. (1983) Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. Proc Natl Acad Sci USA 80, 6972.
18. FURUYAMA T., INAGAKI S., KOSUGI A, et al. (1996) Identification of a novel transmembrane semaphorin expressed on lymphocytes. J Biol Chem 271, 33 376.
19. NODA S., NAGATA-NARUMIYA T., KOSUGI A, et al. (1995) Do structural changes of T cell receptor complex occur in tumor-bearing state? Jpn J Cancer Res 86, 383.
20. LETOURNEUR F. & KLAUSNER R.D. (1992) Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3ε. Scienee 255, 79.
21. WEGENER A.-M., WEGNER A.-M.K., LETOURNEUR F, et al. (1992) The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68, 83.
22. SHORES E.W., HUANG K., TRAN T., LEE E., GRINBERG A. & LOVE P.E. (1994) Role of TCR ζ chain in T cell development and selection. Science 266, 1047.
23. MALISSEN M., GILLET A., ROCHA B, et al. (1993) T cell development in mice lacking the CD3-ζ/η gene. EMBO J 12, 4347.
24. OHNO H., AOE T., TAKI S. et al. (1993) Developmental and functional impairment of T cells in mice lacking CD3ζ chains. EMBO J 12, 4357.
25. - cells. Eur J Immunol 24, 1903.