Symmetrical synovial fluid cell cytokine messenger RNA expression in rheumatoid arthritis: Analysis by reverse transcription/polymerase chain reaction

British Journal of Rheumatology

Volumn 36, Issue 2, 1997, Pages 170-173

  Sew Hoy, M D ^a   Williams, J L ^b   Kirkham, B W ^a  

^a QUEEN ELIZABETH HOSPITAL   (Australia)

^b ST GEORGE HOSPITAL   (Australia)

Author keywords

Cytokines; Polymerase chain reaction; Rheumatoid arthritis

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; KNEE; LEUKOCYTE; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CYTOKINES; FEMALE; HUMANS; KNEE JOINT; LEUKOCYTE COUNT; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNOVIAL FLUID; T-LYMPHOCYTES;

EID: 0030759748     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Brennan FM, Field M, Chu CQ, Feldmann M, Maini RM. Cytokine expression in rheumatoid arthritis. Br J Rheumatol 1991;30(suppl. 1):76-80.
2. Miossec P, Naviliat M, D'Angeac AD et al. Low levels of interleukin-4 and high levels of transforming growth factor B in rheumatoid joints. Arthritis Rheum 1990;33:1180-7.
3. Balkwill FR, Burke F. The cytokine network. Immunol Today 1989;10:299-304.
4. Mossman TR. Cytokines: Is there biological meaning? Curr Opin Immunol 1991;3:311-4.
5. Yamamura M, Uyemura K, Deans RJ et al. Defining protective responses to pathogens: Cytokine profiles in leprosy patients. Science 1991;254;277-9.
6. Kelso A. Th1 and Th2 subsets: paradigms lost? Immunol Today 1995;16:374-9.
7. Dallman MJ, Larsen CP, Morris PJ. Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction. J Exp Med 1991;174:493-6.
8. Troutt AB, Kelso A. Enumeration of lymphokine mRNA-containing cells in vivo in a murine graft-versus-host lesion using the PCR. Proc Natl Acad Sci USA 1992;89:5276-80.
9. Firestein GS, Zvaifler NJ. How important are T cells in chronic rheumatoid arthritis? Arthritis Rheum 1990;33:768-73.
10. Chen E, Keystone EC, Fish EN. Restricted cytokine expression in rheumatoid arthritis. Arthritis Rheum 1993;36:901-10.
11. Simon AK, Seipelt E, Sieper J. Divergent T-cell cytokine patterns in inflammatory arthritis. Proc Natl Acad Sci USA 1994;91:8562-6.
12. Wang AM, Doyle MV, Mark DF. Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci USA 1989;86:9717-21.
13. Ulfgren A-K, Lindblad S, Klareskog L, Andersson J, Andersson U. Detection of cytokine producing cells in the synovial membrane from patients with rheumatoid arthritis. Ann Rheum Dis 1995;54:654-61.
14. Yanni G, Farahat MNMR, Poston RN, Panayi GS. Intramuscular gold decreases cytokine expression and macrophage numbers in the rheumatoid synovial membrane. Ann Rheum Dis 1994;53:315-22.
15. Quale AJ, Choarat P, Moissec P, Kjeldson-Kragh J, Natvig JB. Rheumatoid inflammatory T cell clones express mostly Th1 but also Th2 and mixed (ThO) cytokine patterns. Scand J Immunol 1993;38:75-82.
16. Katsikis PD, Chu CQ, Brennan F, Maini RN, Feldmann M. Immunoregulatory role of interleukin-10 (IL-10) in rheumatoid arthritis. J Exp Med 1994;179:1517-27.
17. Toufic R, Krakowski M, Piccirillo C, Lin Jia-You, Owens T. TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J Immunol 1995;154:955-63.