An homogeneous assay for measuring the uptake and efflux of radiolabelled drugs in adherent cells

Journal of Biochemical and Biophysical Methods

Volumn 34, Issue 3, 1997, Pages 177-187

  Graves, R ^b   Davies, R ^b   Owen, P ^b   Clynes, M ^a   Cleary, I ^a   O'Beirne, G ^b  

^a DUBLIN CITY UNIVERSITY   (Ireland)

^b GENERAL ELECTRIC COMPANY   (United States)

Author keywords

14C adriamycin uptake; Cytostar T; Efflux measurement; Homogenous uptake; MDR; Scintillating microplate

Indexed keywords

CARBON 14; DOXORUBICIN;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG MONITORING; DRUG UPTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; LUNG CARCINOMA; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; SCINTILLATION; SQUAMOUS CELL CARCINOMA;

ANTIBIOTICS, ANTINEOPLASTIC; CARBON RADIOISOTOPES; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL DIVISION; CELL SURVIVAL; CYCLOSPORINE; DOXORUBICIN; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; HUMANS; P-GLYCOPROTEIN; THYMIDINE; VERAPAMIL;

EID: 0030758994     PISSN: 0165022X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-022X(97)01213-X     Document Type: Article

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