Radical modulation activity of benzo[a] phenothiazine

Anticancer Research

Volumn 17, Issue 4 A, 1997, Pages 2539-2543

  Satoh, Kazue ^a   Sakagami, Hiroshi ^b   Motohashi, Noboru ^c  

^a SHOWA UNIVERSITY   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^c MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

12H benzo a phenothiazine; Apoptosis; Ascorbate; Differentiation; Hydroxyl radical; Superoxide anion

Indexed keywords

ASCORBIC ACID; BENZYLIDENE DERIVATIVE; CHLORPROMAZINE; FREE RADICAL; HYDROXYL RADICAL; PHENOTHIAZINE; SUPEROXIDE;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; LEUKEMIA CELL LINE; MONOCYTE; MYELOID LEUKEMIA; PRIORITY JOURNAL; SCAVENGING SYSTEM;

ANTIOXIDANTS; ASCORBIC ACID; CHLORPROMAZINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GALLIC ACID; HYDROGEN-ION CONCENTRATION; HYDROXYL RADICAL; PHENOTHIAZINES; SOLVENTS; SUPEROXIDES;

EID: 0030758560     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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2. Motohashi N: Antitumor activities of phenothiazines. In: Phenothiazines and 1,4-benzothiazines. Chemical and biological aspects. (Gupta RR ed.). Amsterdam, Elsevier Science Publishers, 1988, pp705-774.
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7. Sakagami H, Satoh K, Fukuchi K, Gomi K and Takeda M: Effect of an iron-chelator on ascorbate-induced cytotoxicity. Free Radic Biol Med 23: 1997.
8. Sakagami H, Satoh K, Hatano T, Yoshida T and Okuda T: Possible role of radical intensity and oxidation potential for gallic acid-induced apoptosis. Anticancer Res 17: 377-380, 1997.
9. Sakagami H, Satoh K, Makino Y, Kojima T and Takeda M: Effect of a-tocopherol on cytotoxicity induced by UV irradiation and antioxidants. Anticancer Res 17: in press, 1997.