Iron accumulation in lung allografts after transplantation

Chest

Volumn 112, Issue 2, 1997, Pages 435-439

  Baz, Maher A ^a   Ghio, Andrew J ^b   Roggli, Victor L ^b   Tapson, Victor F ^b   Piantadosi, Claude A ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Fibrosis; Iron overload; Lung transplantation; Reactive oxygen species

Indexed keywords

AGED; ALLOGRAFT; ARTICLE; BRONCHIOLITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FIBROSIS; HEMOSIDEROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IRON OVERLOAD; IRON TRANSPORT; LUNG BIOPSY; LUNG TRANSPLANTATION; MICROSCOPIC ANATOMY; PRIORITY JOURNAL;

EID: 0030757818     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.112.2.435     Document Type: Article

References (27)

1. Hosenpud JD, Novick RJ, Breen TJ, et al. The registry of the International Society for Heart and Lung Transplantation: 11th official report. J Heart Lung Transplant 1994; 13:561-70
2. Duncan SR, Paradis IL, Yousem SA, et al. Sequelae of cytomegalovirus pulmonary infections in lung allograft recipients. Am Rev Respir Dis 1992; 146:1419-25
3. Scott JP, Higgenbottam TW, Sharples L, et al. Risk factors for obliterative bronchiolitis in heart-lung transplant recipients. Transplant 1991; 51:813-17
4. Baz MA, Tapson VF, Roggli VL, et al. Glutathione depletion in epithelial lining fluid of lung allograft patients. Am J Respir Crit Care Med 1996; 153:742-46
5. Cutz E. Idiopathic pulmonary hemosiderosis and related disorders in infancy and childhood. Perspect Pediatr Pathol 1987; 11:48-81
6. Weintraub LR, Goral A, Grasso J, et al. Pathogenesis of hepatic fibrosis in experimental iron overload. Br J Haematol 1985; 59:321-31
7. Yousem SA, Berry GJ, Brunt EM, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: lung rejection study group. J Heart Transplant 1990; 9:593-601
8. Rennard SI, Basset G, Lecossier D, et al. Estimation of the apparent volume of epithelial lining fluid recovered by bronchoalveolar lavage using urea as marker of dilution. J Appl Physiol 1986; 60:532-38
9. Kiernan JA. Histological and histochemical methods: theory and practice. New York: Pergamon Press, 1990; 225-27
10. Ryan TP, Aust SD. The role of iron in oxygen-mediated toxicities. Crit Rev Toxicol 1992; 22:119-41
11. Baliga R, Ueda N, Shah SV. Increase in bleomycin-detectable iron in ischemia/reperfusion injury to rat kidneys. Biochem J 1993; 291:901-05
12. Healing G, Gower J, Fuller B, et al. Intracellular iron redistribution: an important determinant of reperfusion damage to rabbit kidneys. Biochem Pharmacol 1990; 39:1239-45
13. Williams RE, Zweier JL, Flaherty JT. Treatment with deferoxamine during ischemia improves functional and metabolic recovery and reduces reperfusion-induced oxygen radical generation in rabbit hearts. Circulation 1991; 83:1006-14
14. Ozaki M, Fuchinoue S, Teraoka S, et al. Mobilization of low-molecular-weight iron and peroxidative damage during ischemia and reoxygenation of the rat liver. Transplant Proc 1994; 26:918-21
15. Conte JV Jr, Katz NM, Foegh ML, et al. Iron chelation therapy and lung transplantation: effects of deferoxamine on lung preservation in canine single lung transplantation. J Thorac Cardiovasc Surg 1991; 101: 1024-29
16. Lescure AM, Proudhon D, Pesey H, et al. Ferritin gene transcription is regulated by iron in soybean cell cultures. Proc Natl Acad Sci USA 1991; 88:8222-26
17. Boden DH, Adamson IYR. Pathways of cellular efflux and particulate clearance after carbon instillation to the lung. J Pathol 1984; 143:117-25
18. Lehnert BE. Pulmonary and thoracic macrophage subpopulations and clearance of particles from the lung. Environ Health Perspect 1992; 97:17-46
19. Harmsen AG, Muggenburg BA, Snipes MB, et al. The role of macrophages in particle translocation from lungs to lymph nodes. Science 1985; 230:1277-80
20. Corry D, Kulkami P, Lipscomb MF. The migration of bronchoalveolar macrophages into hilar lymph nodes. Am J Pathol 1984; 115:321-28
21. Herve P, Silbert D, Cerrina J, et al. Impairment of bronchial mucociliary clearance in long-term survivors of heart/lung and double-lung transplantation. Chest 1993; 103:59-63
22. Bacon BR, Britton RS. The pathology of heptic iron overload: a free radical-mediated process? Hepatology 1990; 119:127-37
23. Chojkier M, Houglum K, Solis-Herruzo J, et al. Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts: a role for lipid peroxidation? J Biol Chem 1989; 264:16957-62
24. Prockop, DJ. Role of iron in the synthesis of collagen in connective tissue. Fed Proc 1971; 30:984-90
25. Hutton JJ, Tappel AL, Udenfriend S. Cofactor and substrate requirements of collagen proline hydroxylase. Arch Biochem Biophys 1967; 118:231-40
26. Ghio AJ, Jaskot RH, Hatch GE. Lung injury after silica instillation is associated with an accumulation of iron in rats. Am J Physiol 1994; 267:L686-92
27. Kennedy JI, Chandler DB, Jackson RM, et al. Reduction in bleomycin-induced lung hydroxyproline content by an iron chelating agent. Chest 1986; 89:123S-25S