The inhibitory effects of aluminum and iron on bone formation, in vivo and in vitro study

Pathophysiology

Volumn 4, Issue 2, 1997, Pages 97-104

  Takeuchi, K ^a   Okada, S ^a   Yukihiro, S ^a   Inoue, H ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Adult rat; Aluminum; Experimental osteopathy; Iron; Nitrilotriacetic acid

Indexed keywords

ALUMINUM; CHELATING AGENT; IRON; NITRILOTRIACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DISEASE; BONE GROWTH; BONE METABOLISM; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EXPERIMENTAL MODEL; IRON CHELATION; KIDNEY FAILURE; MALE; NONHUMAN; OSSIFICATION; OSTEOMALACIA; PRIORITY JOURNAL; RAT;

EID: 0030757464     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4680(97)00164-8     Document Type: Article

References (37)

1. A.C. Alfrey G.R. Legendre W.D. Kaehny The dialysis encephalopathy syndrome. Possible aluminum intoxication N. Engl. J. Med. 294 1976 184 188
2. H.J. Baluarte A.B. Gruskin L. Hiner C.M. Foley W.D. Grover Encephalopathy in children with chronic renal failure Proc. Clin. Dial. Transplant Forum 7 1977 95 98
3. A.I.K. Short R.J. Winney J.S. Robson Reversible microcytic hypochromic anemia in dialysis patients due to aluminum intoxication Proc. Eur. Dial. Transplant Assoc. 17 1980 226
4. D.N.S. Kerr J. Walls H. Ellis W. Simpson P.R. Uldall M.K. Ward Bone disease in patients undergoing regular hemodialysis J. Bone Joint Surg. [Br] 51B 1969 578
5. E.M. Clarkson V.A. Luvk W.V. Hyson R.R. Bailey J.B. Eastwood J.S. Woodhead V.R. Clements J.L.H. O'Riordan H.E. de Wardner The effect of aluminum hydroxide on calcium, phosphorus and aluminum balances, the serum parathyroid honnone concentration and the aluminum content of bone in patients with chronic renal failure Clin. Sci. 43 1972 519 531
6. G. Cournot-Witmer J. Zingraff J.J. Plachot F. Escaig R. LeFerre P. Boumati A. Bourdreau M. Garabedian P. Galle R. Bourdon T. Drueke S. Balsan Aluminum localization in bone from hemodialyzed patients: Relationship to matrix mineralization Kidney Int. 20 1981 375 385
7. A.B. Hodsman D.J. Sherrad A.C. Alfrey S. Ott A.S. Brickman N.L. Miller N.A. Maloney J.W. Coburn Bone aluminum and histomorphometric features of renal osteodystrophy J. Clin. Endocrinol. Metab. 54 1982 539 546
8. S.M. Ott N.A. Maloney J.W. Coburn A.C. Alfrey D.J. Sherrard The prevalence of bone aluminum deposition in renal osteodystrophy and its relation to the response of calcitriol therapy N. Eng. J. Med. 307 1982 709 713
9. M.K. Ward T.G. Feest H.A. Ellis I.S. Parkinson D.N.S. Kerr Ostcomalacic dialysis osteodystrophy: Evidence for a water-borne aetiological agent, probably aluminum Lancet 1 1978 841 845
10. G.M. Gratwick P.G. Bullough W.H.O. Bohne A.L. Markenson C.M. Peterson Thalassemic osteoarthropathy Ann. Intern. Med. 88 1987 494 501
11. A.M. Pierides M.P. Myli Iron and aluminum osteomalacia in haemodialysis patients N. Engl. J. Med. 310 1984 323
12. M.C. de Vernejoul R. Girot J. Gueris L. Cancela S. Bang J. Bielakoff C. Mautalen D. Goldberg L. Miravet Calcium phosphate metabolism and bone disease in patients with homozygous thalassemia J. Clin. Endocrinol. Metab. 54 1982 276 281
13. G. Roudier Y. Hany J.Y. Louboutin B. Ferrand M. Bourel Histomorphometric et manifestrations articulaires de I'hemochromatose idiopathique Rev. Rheu. Mal. Osteoartic. 46 1979 91 99
14. S. Yukihiro S. Okada K. Takeuchi H. Inoue Experimental osteodystrophy of chronic renal failure induced by aluminum- and ferric nitrirotriacetate in Wistar rats Path. Int. 45 1995 19 25
15. M. Awai M. Narasaki Y. Yamanoi S. Seno Induction of diabetes in animals by parenteral administration of ferric nitrirotriacetate Am. J. Pathol. 95 1979 663 674
16. A. Kawai A new established human osteosarcoma cell line with osteoblastic properties Clin. Ortho. Res. 259 1990 256 267
17. O.H. Lowry N.R. Roberts M.L. Wu W.S. Hixon E.J. Crawford The quantitative histochemistry of brain II. Enzyme measurements J. Biol. Chem. 207 1954 19
18. N. Yasui P.D. Benya M.E. Nimni Coordinate regulation of IX and is type II collagen synthesis during growth of chick chondrocytes in retinoic acid or 5-bromo-2′deoxyuridine J. Biol. Chem. 261 1986 7997 8001
19. M.C. de Vernejoul A. Pointllart C.C. Golenzer C. Morieux J. Bielakoff D. Modrowski L. Miravet Effects of iron overload on bone remodeling in pigs Am. J. Pathol. 116 1984 377 384
20. J. Morrissey M. Rothstein G. Mayor E. Slatopolsky Suppression of parathyroid hormone secretion by aluminum Kidney Int. 23 1983 699 704
21. Y.L. Chan A.C. Alfrey S. Posen D. Lissner E. Hills C.R. Dunstan R.A. Evans Effect of aluminum on normal and uremic rats: Tissue distribution, vitamin D metabolites, and quantitative bone histology Calcif. Tissue Int. 35 1983 344 351
22. J.C.M. Chan M. Jacob S. Brown J. Savory M.R. Wills Aluminum metabolism in rats: effects of vitamin D, Dihydrotachysterol, 1,25-dihydroxyvitamin D and phosphate binders Nephron 48 1988 61 64
23. W.G. Goodman D.A. Henry R. Horst R.K. Nudelman A.C. Alfrey J.W. Coburn Parenteral aluminum administration in the dog: II Induction of osteomalacia and effect on vitamin D metabolism Kidney Int. 25 1984 370 375
24. H.A. Ellis J.H. McCarthy J. Herrington Bone aluminum in haemodialysed patients and in rats injected with aluminum chloride: relationship to impaired mineralization J. Clin. Pathol. 32 1979 832 839
25. L.D. Quarles V.W. Dennis H.J. Gitelman J.M. Harrelson M.K. Drezner Aluminum deposition at the osteoid bone interface J. Clin. Invest. 75 1985 1441 1447
26. H.S. Talwar H. Reddi J. Menczel J.R. Thomas J.L. Meyer Influence of aluminum on mineralization during matrix-induced bone development Kidney Int. 29 1986 1038 1042
27. W.G. Goodman Short-term aluminum administration in the rat: Reductions in bone formation without osteomalacia J. Lab. Clin. Med. 103 1984 749 757
28. M. Lieberherr B. Grosse G. Cournot-Witmer M.P.M. Hermann-Erlee S. Balsan Aliminum action on mouse bone cell metabolism and response to PTH and 1,25(OH)2D3 Kidney Int. 31 1987 736 743
29. A.J. Felsenfeld J.M. Harrelson R.A. Gutman S.A. Wells M.K. Drenzner Osteomalacia after parathyroidectomy in patients with uremia Ann. Intern. Med. 96 1982 34 39
30. J.A. Kraut J.H. Shinaberger F.R. Singer D.J. Sherrard J. Saxton A.B. Hodsman J.H. Miller J.W. Coburn Reduced parathyroid hormone response to acute hypocalcemia in dialysis osteomalacia Kidney Int. 19 1981 130
31. C.E. Cann S.G. Prussin G.S. Gordan Aluminum uptake by parathyroid glands J. Clin. Endocrinol. Metab. 49 1979 543 545
32. M. Rodriguez V. Lorenzo A.J. Felsenfeld F. Llach Effect of parathyroidectomy on aluminum toxicity and azotemic bone disease in rat J. Bone Min. Res. 5 1990 379 386
33. W.G. Goodman Thyroparathyroidectomy modifies the skeletal response to aluminum loading in the rat Kidney Int. 31 1987 923 929
34. Y. Ebina S. Okada S. Hamazaki Y. Toda O. Midorikawa Impairement of bone formation with aluminum and ferric nitrilotriacetate complexes Calcif. Tissue Int. 48 1991 28 36
35. J.F. Mahony J.M. Hayes J.P. Ingham S. Posen Hypophosphataemic osteomalacia in patients receiving haemodialysis Br. Med. J. 2 1976 142 144
36. M.C. de Vernejoul R. Belenguer H. Halkidou A. Buisine J. Bielakoff D. Modrowski L. Miravet Histomorphometric evidence of deleterious of aluminum on osteoblasts Bone 6 1985 15 20
37. J.B. Cannata I.R. Olaizola C. Gomez-Alonso P. Menendez-Fraga M. Alonso-Suarez J.B. Diaz-Lopez Serum aluminum transport and aluminum uptake in chronic renal failure: Role of iron and aluminum metabolism Nephron 65 1993 141 146