A simple and practical approach to the synthesis of the marine sponge pigment fascaplysin and related compounds

Tetrahedron Letters

Volumn 38, Issue 30, 1997, Pages 5339-5342

  Radchenko, Oleg S ^a   Novikov, Vyacheslav L ^a   Elyakov, George B ^a  

^a RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BETA CARBOLINE DERIVATIVE; CYTOTOXIC AGENT; FASCAPLYSIN; INDOLOQUINOLINE DERIVATIVE; KETONE; PIGMENT; TRYPTAMINE;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; MARINE ENVIRONMENT; OXIDATION; SPONGE; TECHNIQUE; TEMPERATURE;

EID: 0030757383     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01167-2     Document Type: Article

References (10)

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3. Gribble, G.W.; Pelcman, B. J. Org. Chem., 1992, 57, 3636-3642.
4. Rocca, P.; Marsais, F.; Godard, A.; Queguiner, G. Tetrahedron Lett., 1993, 34, 7917-7918.
5. Molina, P.; Fresneda, P.M.; Garciazafra, S.; Almendros, P. Tetrahedron Lett., 1994, 35, 8851-8854.
6. Pabuccuoglu, V.; Rozwadowska, M.D.; Brossi, A.; Clark, A.; Hufford, C.D.; George, C.; Flippen-Anderson, J.L. Arch. Pharm. (Weinheim), 1991, 324, 29-33.
7. +, 97), 236 (19), 235 (100), 207 (14), 206 (24).
8. 6): 3.87 (s, 3H, OMe), 6.45 (s, 1H, H-5), 7.08 (d, 1H, J=7.0 Hz, H-4), 7.39 (dt, 1H, J=1. 1, 7.2 Hz, H-11), 7.78 (dd, 1H, J=1.2, 7.4 Hz, H-13), 7.79 (dt, 1H, J=1.2, 7.4 Hz, H-12), 7.93 (s, 1H, H-8), 7.96 (dd, 1H, J=1.1, 7.2 Hz, H-10), 8.34 (d, 1H, J=7.0 Hz, H-3).
9. 3COOD), δ: 102.1, 106.4, 106.6, 108.0, 111.1, 111.3, 111.6, 115.6, 117.5, 118.4, 120.8, 121.5, 126.3, 132.5, 136.8, 208.8.
10. 3COOD): 4.36 (s, 3H, OMe), 7.67 (s, 1H, H-5), 7.78 (dt, 1H, J=1.2, 6.5 Hz, H-12), 7.99 (dt, 1H, J=1.2, 6.5 Hz, H-11), 8.06 (dd, 1H, J=1.2, 6.5 Hz, H-13), 8.12 (dd, 1H, J=1.2, 6.5 Hz, H-10), 8.33 (d, 1H, J=6.5 Hz, H-4), 8.73 (s, 1H, H-8), 8.83 (d, 1H, J=6.5 Hz, H-3).