T-cell receptor β chain variability in bone marrow and peripheral blood in severe acquired aplastic anemia

Blood Cells, Molecules and Diseases

Volumn 23, Issue 1, 1997, Pages 110-122

  Manz, Chantal Y ^a   Dietrich, Pierre Yves ^b   Schnuriger, Valérie ^b   Nissen, Catherine ^a   Wodnar Filipowicz, Aleksandra ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Aplastic anemia; Complementarity determining region 3; T cell receptor; V chain

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ADULT; AGED; APLASTIC ANEMIA; ARTICLE; BETA CHAIN; BONE MARROW; CLINICAL ARTICLE; CONTROLLED STUDY; GENETIC VARIABILITY; HEMATOPOIESIS; HUMAN; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; T LYMPHOCYTE;

TRIXIS;

EID: 0030757260     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.1997.0127     Document Type: Article

References (50)

1. Nissen C, Gratwohl A, Speck B. Management of aplastic anaemia. Eur J Haematol. 46:1991;193-197.
2. Young N S, Barrett A J. The treatment of severe acquired aplastic anemia. Blood. 85:1995;3367-3377.
3. Maciejewski J P, Hibbs J R, Anderson S, Katevas P, Young N S. Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure. Exp Hematol. 22:1994;1102-1110.
4. Zoumbos N, Gascon P, Djeu J, Young N S. Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo. Proc Natl Acad Sci U S A. 82:1985;788-794.
5. Schultz J C, Shahidi N T. Detection of tumor necrosis factor-α in bone marrow plasma and peripheral blood plasma from patients with aplastic anemia. Am J Hematol. 45:1994;32-38.
6. Nisticò A, Young N S. γ-interferon gene expression in the bone marrow of patients with aplastic anemia. Ann Intern Med. 120:1994;463-469.
7. Nakao S, Yamaguchi M, Shiobara S. Interferon-γ gene expression in unstimulated bone marrow mononuclear cells predicts a good response to cyclosporine therapy in aplastic anemia. Blood. 79:1992;2532-2535.
8. Ascensao J, Pahwa R, Kagan W, Hansen J, Moore M AS, Good R. Aplastic anaemia: Evidence for an immunological mechanism. Lancet. 1:1976;669.
9. Hoffman R, Zanjani E D, Lutton J D, Zalusky R, Wasserman L R. Suppression of erythroid-colony formation by lymphocytes from patients with aplastic anemia. N Engl J Med. 269:1977;10-13.
10. Viale M, Merli A, Bacigalupo A. Analysis at the clonal level of T-cell phenotype and functions in severe aplastic anemia patients. Blood. 78:1991;1268-1274.
11. +. Exp Hematol. 23:1995;433-438.
12. Nakao S, Yamaguchi M, Saito M. HLA-DR2 predicts a favorable response to cyclosporine therapy in patients with bone marrow failure. Am J Hematol. 40:1992;239.
13. Nimer S D, Ireland P, Meshkinpour A, Frane M. An increased HLA DR2 frequency is seen in aplastic anemia patients. Blood. 84:1994;923-927.
14. Young N S. Aplastic anemia. Lancet. 346:1995;228-232.
15. Davis M M, Bjorkman P J. T-cell antigen receptor genes and T-cell recognition. Nature. 334:1988;395-402.
16. Chothia C, Boswell D R, Lesk A M. The outline structure of the T-cell α/β receptor. EMBO J. 7:1988;3745-3755.
17. Choi Y, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction ofStaphylococcus aureus. Proc Natl Acad Sci USA. 86:1989;8941-8945.
18. Genevee C, Diu A, Nierat J. An experimentally validated panel of subfamily-specific oligonucleotide primers (V alpha 1-w29/V beta 1-w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction. Eur J Immunol. 22:1992;1261-1269.
19. Acha-Orbea H, Mitchell D J, Timmermann L. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell. 54:1988;263-273.
20. Burns F R, Li X, Shen N. Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar Vα and Vβ chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different. J Exp Med. 169:1989;27-39.
21. Conrad B, Weidmann E, Trucco G. Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology. Nature. 371:1994;351-355.
22. Kotzin B L, Karuturi S, Chou Y K. Preferential T-cell receptor β-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis. Proc Natl Acad Sci U S A. 88:1991;9161-9165.
23. Ben-Nun A, Liblau R S, Cohen L. Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals. Proc Natl Acad Sci U S A. 88:1991;2466-2470.
24. Oksenberg J R, Panzara M A, Begovich A B. Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature. 362:1993;68-70.
25. Paliard X, West S G, Lafferty J A. Evidence for the effects of a superantigen in rheumatoid arthritis. Science. 253:1991;325-329.
26. Uematsu Y, Wege H, Straus A. The T-cell-receptor repertoire in the synovial fluid of a patient with rheumatoid arthritis is polyclonal. Proc Natl Acad Sci USA. 88:1991;8534-8538.
27. Dietrich P Y, Caignard A, Lim A. In vivo T-cell clonal amplification at time of acute graft-versus-host disease. Blood. 84:1994;2815-2820.
28. Abe J, Kotzin B L, Jujo K. Selective expansion of T cells expressing T-cell receptor variable regions Vβ2 and Vβ8 in Kawasaki disease. Proc Natl Acad Sci USA. 89:1992;4066-4070.
29. +. Proc Natl Acad Sci U S A. 91:1994;9282-9286.
30. +. J Exp Med. 181:1995;1863-1868.
31. Pannetier C, Even J, Kourilsky P. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol Today. 16:1995;176-181.
32. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
33. Dietrich P Y, Caignard A, Diu A. Analysis of T-cell receptor variability in transplanted patients with acute graft-versus-host disease. Blood. 80:1992;2419-2424.
34. Pannetier C, Cochet M, Darche S, Casrouge A, Zoller M, Kourilsky P. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci U S A. 90:1993;4319-4323.
35. Even J, Lim A, Puisieux I. T cell repertoires in healthy and diseased human tissues analyzed by CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases. Res Immunol. 146:1995;65-80.
36. --. Proc Natl Acad Sci USA. 90:1993;11787-11791.
37. ++. J Immunol. 151:1993;5762-5769.
38. ++. J Immunol. 154:1995;6182-6190.
39. Gold D P. TcR V gene usage in autoimmunity. Current Opinion in Immunology. 6:1994;907-912.
40. Sensi M, Parmiani G. Analysis of TCR usage in human tumors: a new tool for assessing tumor-specific immune responses. Immunol Today. 16:1995;588-595.
41. Takamatsu H, Nakao S, Yamaguchi M. Analysis of the T-cell clonotype in the bone marrow of immune-mediated aplastic anemia: Identification of a T-cell clone that preferentially proliferates in the bone marrow of a cyclosporine-dependent aplastic anemia patient. Blood. 84:1994.
42. Melenhorst J J, Fibbe W E, Van den Elsen P J, Struyk R, Willemze L, Landegent J E. Analysis of T-cell clonality by TCRβ PCR in bone marrow of patients with aplastic anemia. Exp Hematol. 23:1995.
43. Romero P, Pannetier C, Herman J, Jongeneel C V, Cerottini J C, Coulie P G. Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1. J Exp Med. 182:1995;1019-1028.
44. +. J Immunol. 150:1993;5494-5500.
45. +. J Immunol. 154:1995;6013-6021.
46. Razvi E S, Welsh R M, McFarland H I. In vivo state of antiviral CTL precursors. Characterization of a cycling cell population containing CTL precursors in immune mice. J Immunol. 154:1995;620-632.
47. Singer J W, Doney K C, Thomas E D. Coculture studies of 16 untransfused patients with aplastic anemia. Blood. 54:1979;180-185.
48. Nissen C, Cornu P, Gratwohl A, Speck B. Peripheral blood cells from patients with aplastic anaemia in partial remission suppress growth of their own bone marrow precursors in culture. Br J Haematol. 45:1980;233-243.
49. Torok-Storb B J, Sieff C, Storb R, Adamson J, Thomas E D. In vitro tests for distinguishing possible immune-mediated aplastic anemia from transfusion-induced sensitization. Blood. 55:1980;211-215.
50. Angevin E, Farace F, Genevée C. Analysis of T-cell-receptor variable gene segment usage in peripheral-blood lymphocytes of advanced cancer patients. Int J Cancer. 54:1993;60-67.