Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells

Biochemical Pharmacology

Volumn 54, Issue 1, 1997, Pages 113-120

  Ren, Zhibin ^a   Elson, Charles E ^b   Gould, Michael N ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cancer chemoprevention; Cancer chemotherapy; Farnesyl protein transferase; Geranylgeranyl protein transferases; Monoterpenes; Perillyl alcohol

Indexed keywords

ENZYME INHIBITOR; GERANYLTRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; PERILLYL ALCOHOL; RAS PROTEIN; TERPENE; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING;

3T3 CELLS; ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; CARRIER PROTEINS; GTP-BINDING PROTEINS; MEVALONIC ACID; MICE; MONOTERPENES; PHOSPHATES; PROTEIN ISOPRENYLATION; RAB GTP-BINDING PROTEINS; RAP GTP-BINDING PROTEINS; RAS PROTEINS; TERPENES; TRANSFERASES;

EID: 0030757145     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00151-2     Document Type: Article

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