P-glycoprotein mediated multidrug resistance assessment by flow-cytometry in malignant hemopathies

Anticancer Research

Volumn 17, Issue 4 A, 1997, Pages 2583-2586

  Tatu, Calin A ^a,c   Paunescu, Virgil ^b   Stanescu, Diana I ^b   Schneider, Francisc ^b  

^a Forslys Group   (Romania)

^b VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c Forslys Group   (Romania)

Author keywords

Flow cytometric assay; Malignant hemopathies; MDR; P glycoprotein

Indexed keywords

CALCIUM ION; DAUNORUBICIN; FLUOROCHROME; GLYCOPROTEIN P; VERAPAMIL;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BLOOD DISEASE; CALCIUM CELL LEVEL; CELL MEMBRANE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; MYELOID LEUKEMIA; NONHODGKIN LYMPHOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RELIABILITY;

CALCIUM; DAUNORUBICIN; DRUG RESISTANCE, MULTIPLE; FLOW CYTOMETRY; FLUORESCENT DYES; HUMANS; LEUKEMIA; LYMPHOMA, NON-HODGKIN; METHODS; P-GLYCOPROTEIN; VERAPAMIL;

EID: 0030757039     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Kellen JA: The phenomenon of multidrug resistance. In: Reversal of Multidrug Resistance in Cancer(Kellen JA, ed.), CRC Press, Boca Raton, 1994, pp1-21.
2. Higgins CF: The multidrug resistance P-glycoprotein. Curr Opin Cell Biol 5: 684-688, 1993.
3. Gottesman MM, Pastan I: The multidrug transporter, a double-edged sword. J Biol Chem 263: 12163-12167, 1988.
4. Gottesman MM, Hrycyna CA: Genetic analysis of the multidrug transporter. Annu Rev Genet 29: 607-649, 1995.
5. Morrow CS, Cowan KH: Drug resistance and its clinical circumvention. In: Cancer Medicine(Holland JF, Frei E III, Bast RC et al eds.) 3rd Edition, Lea and Febiger Philadelphia, 1993, pp 618-631.
6. Kellen JA: Multidrug resistance in human malignancies In: Reversal of Multidrug Resistance in Cancer(Kellen JA, ed.), CRC Press, Boca Raton, 1994, pp 93-127.
7. Paunescu V, Tatu CA, Medrea DP, lonita H, Stanescu DI: A striking correlation of CD23 and CDS molecules expression in non-Hodgkin lymphomas. Fiziologia-Physiology, 5: 57-61, 1995.
8. Patrick C, Ash R, Libnoch J, Keller R: Clinical cytometry and immunophenotyping. Pathol Immunopathol Res 6: 64-76, 1987.
9. Hedley DW: Assays of cancer chemotherapy resistance. In: Handbook of Flow Cytometry Methods (Robinson JP, ed.), Wiley-Liss, New York, 1994, pp 191-195.
10. Krishan A, Sauerteig A, Gordon K, Swinkin C: Flow-cytometric monitoring of cellular anthracycline accumulation in murine leukemic cells. Cancer Res, 46: 1768-1773, 1986.
11. Tatu CA, Paunescu V, lonita H, Medrea DP, Stanescu DI: A flowcytometric assessment of mdr phenotype in small cell lymphocytic non-Hodgkin lymphoma(abstract 3033). The 9th International Congress of Immunology, 23-29 July, San Francisco, CA, USA, 1995.