Comparison of the biological properties of two anti-mucin-1 antibodies prepared for imaging and therapy

Cancer Immunology Immunotherapy

Volumn 44, Issue 6, 1997, Pages 323-328

  Pietersz, Geoffrey A ^a   Wenjun, Li ^a   Krauer, Kenia ^a   Baker, Terry ^b   Wreschner, Daniel ^c   McKenzie, Ian F C ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b UCB PHARMA   (Belgium)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Anti mucin 1 antibodies; Biological properties; Imaging

Indexed keywords

ANTINEOPLASTIC AGENT; EPITOPE; IDARUBICIN; MONOCLONAL ANTIBODY BC 2; MONOCLONAL ANTIBODY HTMO1; MUCIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY LABELING; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; CELLULAR DISTRIBUTION; DISSOCIATION; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

3T3 CELLS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS; CA-15-3 ANTIGEN; EPITOPES; IMAGE PROCESSING, COMPUTER-ASSISTED; IODINE RADIOISOTOPES; KINETICS; MICE; MICE, INBRED BALB C; TEMPERATURE; TISSUE DISTRIBUTION;

EID: 0030756889     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050389     Document Type: Article

References (17)

1. Adair JR, Owen RJ, Baker TS, Lyons AH, Menendez AT (1992) Anti-human milk fat globule humanised antibodies. European patent application, EPA 0 534 742 A1
2. Andrew SM, Johnstone RW, Russell SM, McKenzie IFC, Pietersz GA (1990) A comparison of in vitro cell binding characteristics of four monoclonal antibodies and their individual tumor localization properties in mice. Cancer Res 50:4423-4428
3. Bayer EA, Wilcheck M (1980) The use of avidin-biotin complex as a tool in molecular biology. Methods Biochem Anal 26:1-45
4. Ey PL, Prowse SJ, Jenkin CR (1978) Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using Protein-A Sepharose. Immunochemistry 15:429-436
5. Graham FC, Bacchetti S, McKinnon R, Stunners C, Cordet B, Goodman HM (1980) Transformation of mammalian cells with DNA using the calcium phosphate technique. In: Baserga R, Croce C, Rovera G (eds) Introduction of macromolecules into viable mammalian cells. Liss, New York
6. Hogarth PM, Henning MM, McKenzie IFC (1982) Alloantigenic phenotype of radiation induced thymomas in the mouse. J Natl Cancer Inst 69:619-625
7. Hunter WM, Greenwood FC (1962) Preparation of iodine-131-labelled human growth hormone of high specific activity. Nature 194:495-498
8. Kulczycki A, Metzger H (1974) The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction. J Exp Med 140:1676-1695
9. Matzku S, Moldenhauer G, Kalthoff H, Canevari S, Colnaghi M, Schuhmacher J, Bihl H (1990) Antibody transport and internalisation into tumors. Br J Cancer 62[Suppl X]:1-5
10. Pietersz GA, McKenzie IFC (1992) Antibody conjugates for the treatment of cancer. Immunol Rev 129:57-80
11. Pietersz GA, Smyth MJ, McKenzie IFC (1988) Immunochemotherapy of a murine tymoma with idarubicin - monoclonal antibody conjugates. Cancer Res 48:926-931
12. Pietersz GA, Rowland A, Smyth MJ, McKenzie IFC (1994) Chemoimmunoconjugates for the treatment of cancer. Adv Immunol 56:301-387
13. Tomonari K, (1988) Rat antibody against a structure functionally related to the mouse T-cell receptor/T3 complex. Immunogenetics 28:455-458
14. Wreschner DH, Tsarfaty I, Hareuveni M, Zaretsky Y, Smorodinsky NI, Weiss M, Horev I, Kotkes P, Zrihan S, Jeltsch JM, Green S, Lathe R, Keyder I (1989) Isolation and characterisation of full length cDNA coding for the H23 breast tumour associated antigen. In: Rich MH, Hager JC, Keyder I (eds) Breast cancer: progress in biology, clinical management and prevention. Kluwer, London New York, pp 41-60
15. Wreschner DH, Hareuveni M, Tsarfaty I, Horev J, Zaretsky J, Kotkes P, Weiss M, Lathe R, Dion AS, Keydar I (1990) Human epithelial tumor antigen cDNA sequences differential splicing may generate multiple protein forms. Eur J Biochem 189:463-473
16. Xing P, Tjandra JJ, Stacker SA, Teh JG, Thompson CH, McLaughlin. McKenzie IFC (1989) Monoclonal antibodies reactive with mucin expressed in breast cancer. Immunol Cell Biol 67:183195
17. Xing P-X, McKenzi IFC (1991) Monoclonal antibodies reactive with breast cancer, mammary mucins and synthetic peptides. In: Ceriani RL (ed) Breast epithelial antigen. Plenum Press, New York