Renal effects of an angiotensin II antagonist in stroke-prone spontaneously hypertensive rat

Nephron

Volumn 76, Issue 4, 1997, Pages 466-471

  Yo, Yoshikage ^a   Moriguchi, Atsushi ^a   Higaki, Jitsuo ^a   Nagano, Masahiro ^a   Nakano, Nobuaki ^a   Kamide, Kei ^a   Yu, Hisahiro ^a   Mikami, Hiroshi ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II type 1 receptor antagonist; Glomerular sclerosis; HR 720; Hypertension; Urinary protein

Indexed keywords

2 BUTYL 4 METHYLTHIO 1 [[2' [[[(PROPYLAMINO)CARBONYL]AMINO]SULFONYL][1,1' BIPHENYL] 4 YL]METHYL] 1H IMIDAZOLE 5 CARBOXYLIC ACID; ANGIOTENSIN II ANTAGONIST; ANTIHYPERTENSIVE AGENT; ENALAPRIL; LOSARTAN POTASSIUM; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; KIDNEY FUNCTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RAT; RENOVASCULAR HYPERTENSION; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE;

ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; BIPHENYL COMPOUNDS; BLOOD PRESSURE; BODY WEIGHT; CEREBROVASCULAR DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; HYPERTENSION; IMIDAZOLES; KIDNEY; KIDNEY FUNCTION TESTS; KIDNEY GLOMERULUS; LOSARTAN; ORGAN SIZE; PROTEINURIA; RATS; RATS, INBRED SHR; RECEPTORS, ANGIOTENSIN; TETRAZOLES; TISSUE EMBEDDING;

EID: 0030755868     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000190230     Document Type: Article

References (29)

1. Erley CM, Haefele U, Heyne N, Braun N, Ris-Icr T: Microalbuminuria in essential hypertension, Reduction by different antihypertensive drugs, Hypertension 1993:21:810-815.
2. Hollenberg NK: Hypertension and the kidney: Determinants of the response to antihypertensive therapy and their implications, Am Heart J 1993:125:604-608.
3. Reams GP, Villarreal D, Wu Z, Wang X, Luger AM, Baur JH: An evaluation of the renal protective effect of manidipinc in the unincphrcc-tomized spontaneously hypertensive rat, Am Heart J 1993;125:620-625.
4. Okamoto K, Hazama F, Yamori Y, Hacbara H, Nagaoka A: Pathogenesis and prevention of stroke in spontaneously hypertensive rats, Clin Sci Mol Med 1975;2(suppl): 161 s- 163s.
5. Volpe M, Camargo MJ, Mueller FB, Campbell WG Jr., Sealey JE, Pecker MS, Laragh JH: Relation of plasma renin to end organ damage and to protection of K feeding in stroke-prone hypertensive rats, Hypertension 1990; 15:318- 326.
6. Masson GMC, Mikasa A, Yasuda H: Experimental vascular disease caused by aldosterone and renin, Endocrinology 1962:71:505-512.
7. Laragh JH, Baer L, Brunner HR, Brenner BM: Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease, Am J Med 1972:52:633-652.
8. Tolins JP, Raij L: Angiotensin converting enzyme inhibitors and progression of chronic renal failure, Kidney Int 1990:38(suppl 30): 118-122.
9. Meyer TW, Anderson S, Rennke HG, Brenner BM: Converting enzyme inhibitor therapy limits progressive glomerular injury in rats with renal insufficiency, Am J Med 1985:79(suppl 3C):31-36.
10. Kohara K, Mikami H, Okuda N, Higaki J, Ogi-hara T: Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat, Hypertension 1993;21:975-979.
11. Kohzuki M, Yasujima M, Yoshida K, Kanazawa M, Abe K: Antihypertensive and antipro-teinuremic effects of losartan in spontaneously hypertensive rats with chronic renal failure, Hypertcns Res 1994;17:173-178.
12. Camargo MJF, Lutterotti N, Pecker MS, James GD, Timmermans PB, Laragh JH: DuP 753 increases survival in spontaneously hypertensive stroke-prone rats fed a high sodium diet, Am J Hypcrtens 1991;4:341S-345S.
13. Jover B, Saladini D, Nafrialdi N, Dupont M, Mimran A: Effect of losartan and cnalapril on renal adaptation to sodium restriction in rat, Am J Physiol 1994;267:F281-288.
14. Fcnoy FJ, Milicic I, Smith RD, Wong PC, Timmermans PB, Roman R: Effects of DuP 753 on renal function of normotensive and spontaneously hypertensive rats, Am J Hypertens 1991;4:321 S-326S.
15. Cogan MG, Xic MH, Liu FY, Wong PC, Timmermans PB: Effects of DuP 753 on proximal nephron and renal transport, Am J Hypertens 1991;4:315S-320S.
16. Li XC, Widdop RE: Regional hemodynamic effects of the ATI receptor antagonist CB-11974 in conscious renal hypertensive rats, Hypertension 1995:26(6 pt 1):989-997.
17. Blants RC, Können KS, Tucker BJ: Angiotensin II effects upon the glomerular microcirculation and ultrafiltration coefficient of the rat, J Clin Invest 1976:57:419-434.
18. Miller PL, Rennkc HG, Meyer TW: Glomerular hypertrophy accelerates hypertensive glomerular injury in rats, Am J Physiol 1991;261: F459-F465.
19. Ray PE, Anguilera G, Kopp JB, Horikoshi S, Klotman PE: Angiotensin II receptor-mediated proliferation of cultured human fetal mcsangial cells, Kidney Int 1991;40:764-771.
20. Wenzel UO, Troschau G, Schoeppc W, Heimchen U, Schwietzer G: Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension, Hypertension 1992;20:233-241.
21. Pelayo JC, Quan AH, Shanlcy PF: Angiotensin II control of the renal microcirculation in rats with reduced renal mass, Am J Physiol 1990; 258:F414-422.
22. Carretero OA, Miyazuki S, Scicli AG: Role of kinins in the acute antihypertensive effect of the converting enzyme inhibitor, captopril, Hypertension 1981;3:18-22.
23. Moore TJ, Crantz FR, Hollenberg NK: Contribution of prostaglandins to the antihypertensive action of captopril in essential hypertension, Hypertension 1981;3:168-173.
24. Deprez P, Guillaume J, Becker R, Corbier A, Didierlaurent S, Fortin M, Frechet D, Hamon G, Hcckmann B, Hcitsch H: Sulfonylureas and sufonylcarbamates as new non-tetrazole angiotensin II recpetor antagonists, Discovery of a highly potent orally active (imidazolylbipheny-lyl) sufonylurea (HR 720), J Med Chem 1995; 38:2357-2377.
25. Hano T, Mizukoshi M, Baba A, Nakamura N, Nishio I: Angiotensin II subtype 1 receptor modulates epinephrine release from isolated rat adrenal gland, Blood Pressure 1994;5: S105-S108.
26. Garcia NH, Garvin JL: Angiotensin 1-7 has a biphasic effect of fluid absorption in the proximal straight tubule, J Am Soc Nephrol 1994;5: 1133-1138.
27. Cheng DY, DeWitt BJ, Dent EL, Nossaman BD, Kadowitz PJ: Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat, Eur J Pharmacol 1994:261:223-227.
28. Stoll M, Steckelings UM, Paul M, Bottari SP, Metzger R, Unger T: The angiotensin AT2 receptor mediates inhibition of cell proliferation in coronary endothelial cells, J Clin Invest 1995;95:651-657.
29. Keiser JA, Bjorkc FA, Hodges JC, Taylor DG Jr.: Renal hemodynamic and excretory responses to PD 123319 and losartan, nonpeptide AT 1 and AT2 subtype-specific angiotensin II ligands, J Pharmacol Exp Thcrap 1992;262: 1154-1160.