Suzuki-type cross-coupling reaction of 1-benzyl-2-iodo-1H-benzimidazoles with aryl boronic acids: A regioselective route to N-alkylated 6-alkoxy-2-aryl-1H-benzimidazoles

Tetrahedron

Volumn 53, Issue 37, 1997, Pages 12755-12764

  Ezquerra, Jesús ^a   Lamas, Carlos ^a   Pastor, Alfredo ^b   García Navío, José L ^b   Vaquero, Juan J ^b  

^a ELI LILLY AND COMPANY   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

LATEOLABRAX JAPONICUS;

EID: 0030755292     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00795-3     Document Type: Article

References (21)

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2. (b) Frachey, G.; Crestini, R.; Bernini, R.; Saladino, R.; Mincione, E. Heterocycles, 1994, 38, 2621.
3. (c) Zhao, M.; Samoc, M.; Prasad, P. N.; Reinhardt, B. A.; Unroe, M. R.; Prazak, M.; Evers, R. C.; Kane, J. J., Jariwala, C.; Sinsky, M. Chem. Mater. 1992, 2, 670.
4. (d) Kondo, J.; Suzuki, N.; Imaoka, T.; Kawasaki, T.; Nakanishi, A.; Kawahara, Y. Anal. Sci. 1994, 10, 17.
5. (a) Landquist, J, K. Imidazoles and Their Benzo Derivatives: Applications as Pharmaceuticals. In Comprehensive Heterocyclic Chemistry, Ed. Katritzky, A. R. and Rees, C. W. Vol. 5, pp 143-183, Pergamon Press, 1984.
6. (b) Denny, W. A.; Rewcastle, G. W.; Baguley, B. J. Med. Chem. 1990, 33, 814.
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8. Göker, H.; Ölgen, S.; Ertan, R.; Akgün, H.; Özbey, S.; Kendi, E.; Topcu, G. J. Heterocyclic Chem. 1995, 32, 1767.
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14. Undheim, K.; Benneche, T. Adv. Heterocycl. Chem. 1996, 62, 305.
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