Cellular and humoral immunity to the 60-kD heat shock protein in inflammatory bowel disease

Digestion

Volumn 58, Issue 5, 1997, Pages 469-475

  Spahn, Thomas W ^a,b   Heimann, Heike ^a   Duchmann, Rainer ^a   van der Zee, Ruurd ^c   zum Büschenfielde, Karl Hermann Meyer ^a   Lohse, Ansgar W ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Autoimmunity; Crohn s disease; Heat shock protein; Mycobacteria; Ulcerative colitis

Indexed keywords

BACTERIAL PROTEIN; HEAT SHOCK PROTEIN;

ADULT; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMORAL IMMUNITY; MYCOBACTERIUM; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; ANTIBODY FORMATION; ANTIGENS, BACTERIAL; CASE-CONTROL STUDIES; CHAPERONIN 60; COLITIS, ULCERATIVE; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MYCOBACTERIUM TUBERCULOSIS;

EID: 0030755110     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000201485     Document Type: Article

References (23)

1. Ellis R: The molecular chaperone concept, Semin Cell Biol 1990;1:1-25.
2. Young R, Elliott T: Stress proteins, infection and immune surveillance, Cell 1989;59:5-8.
3. van Eden W: Heat-shock proteins and the immune system, Immunol Rev 1991;121:5-28.
4. Kaufmann S: Heat shock proteins and the immune response, ImmunolTodav 1990; 11:129-136.
5. Kaufmann S, Vath U, Thole J, van Embden J, Emmrich F: Enumeration of the T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64-kDa protein, Eur J Immunol 1987; 17:351-357.
6. van Eden W, Thole J, van der Zee R, Noordzij A, van Embden JDA, Henscn EJ, Cohen 1R: Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis, Nature 1988;331:171-173.
7. Elias D, Maekovits D, Rcshef T, van der Zee R, Cohen I; Induction and therapy of autoimmune diabetes in non-obese diabetic (NOD/Lt) mice by a 65-kD heal shock protein, Proc Natl AcadSci USA 1990;87:1576-1580.
8. Elias D, Rcshef T, Birk O, van der Zee R, Walker M, Cohen I: Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein, Proc Natl Acad Sci USA 1991;88:3088-3091.
9. Gitnick G: Current views of the etiology of inflammatory bowel disease, Semin Pediatr Surg 1994;3:2-7.
10. Kreuzpaintner G, Das P, Stronkhorst A, Slob A, Strohmeyer G: Effect of intestinal resection on scrum antibodies to the mycobacterial 45/ 48 kilodalton doublet antigen in Crohn's disease, Gut 1995;37:361-366.
11. Seldenrijk C, Drexhage H, Meuwisscn S, Mei-jer C: T-cellular immune reactions (in macrophage inhibition factor assay) against Mycobacterium paratubcrculosis, Mycobacterium kan-sasii, Mycobacterium tuberculosis, Mycobacterium avium in patients with chronic inflammatory bowel disease, Gut 1990;31:529-535.
12. Kobayashi K, Brown W, Brennan P, Blaser M: Serum antibodies to mycobacterial antigens in active Crohn’s disease, Gastroenterology 1988: 94:1404-1411.
13. Markesich DC, Sawai ET, Beutel JS, Graham DY: Investigations on etiology of Crohn’s disease: Humoral immune response to stress (heat shock) proteins, Dig Dis Sci 1991:36:454-460.
14. Stevens TR, Winrow VR, Blake DR, Rampton DS: Circulating antibodies to heat-shock protein 60 in Crohn's disease and ulcerative colitis, Clin Exp Immunol 1992;90:271-274.
15. dc GraefT-Meeder E, van der Zee R, Rijkers G, Schuurman HJ, Ruin W, Bijlnma JWJ, Zegern BJM, van Eden W: Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis, Lancet 1991;337:1368-1372.
16. Baca-Estrada M, Gupta R, Stead R, Croitoru K: Intestinal expression and cellular immune responses to human heat-shock protein 60 in Crohn’s disease, Dig Dis Sci 1994:39:498-506.
17. Brudzynski K: Insulitis-caused redistribution of heat-shock protein HSP60 inside bcta-cells correlates with induction of HPS60 autoantibodies, Diabetes 1993;42:908-913.
18. Hermann E, Mavet W, Lohse A, Grevenstein J, Meyer zum Biischenfeldc K-H, Fleischer B: Proliferative response of synovial fluid and peripheral blood mononuclear cells to arthrito-genic and non-arthritogenic microbial agents and to the 65-kDa mycobacterial heat shock protein, Med Microbiol Immunol (Berl) 1990; 179:215-224.
19. Hermann E, Lohse A, van der Zee R, van Eden W, Mayet WJ, Probst P, Poralla T, Meyer zum Biischenfelde K-H, Fleischer B: Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells, Eur J Immunol 1991:21:2139-2143.
20. Karlsson Parra A, Soderstrom K, Ferm M, Iva-nyi J, Kiessling R, Klareskog L: Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patients, Scand J Immunol 1990:31:283-288.
21. Lohse A, Diencs H, Herkel J, Hermann E, van Eden W, Meyer zum Biischenfelde K-H: Expression of the 60 kDa heat shock protein in normal and inflamed liver, J Hepatol 1993; 19: 159-166.
22. Kostinas J, Winrow V, Bird G, Lau J, Port-mann B, Blake D: Hepatic 65 kDa heat shock protein and corresponding IgA antibody in alcohol hepatitis, Hepatology 1993; 17:1047-1051.
23. dc GraefT-Meeder E, van Eden W, Rijkers G, Prakken BJ, Kuis W, Voorhorst-Ogink MM, van der Zee R, Schuurman HJ, Helders PJ, Zegcrs BJM: Juvenile chronic arthritis: T cell reac:ivity to human 1ISP60 in patients with a favorable course of arthritis, J Clin Invest 1995:95:934-940.