Anti-HIV env immunities elicited by nucleic acid vaccines

Vaccine

Volumn 15, Issue 8, 1997, Pages 884-887

  Shiver, John W ^a   Davies, Mary Ellen ^a   Yasutomi, Yasuhiro ^b   Perry, Helen C ^a   Freed, Daniel C ^a   Letvin, Norman L ^b   Liu, Margaret A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Cytotoxic T lymphocyte (CTL); DNA vaccines; gp120; gp160; Helper T cells; HIV

Indexed keywords

DNA VACCINE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 160; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PLASMID DNA; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRADERMAL DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; VIRUS ENVELOPE;

AIDS VACCINES; ANIMALS; DNA, VIRAL; GENE PRODUCTS, ENV; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; MACACA MULATTA; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER; VACCINES, DNA; VACCINES, SYNTHETIC;

EID: 0030754098     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00251-4     Document Type: Conference Paper

References (12)

1. Ulmer, J.B., Donnelly, J.J. and Parker, S.E. et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993, 259, 1745-1749
2. Ulmer, J.B., Deck, R.R., DeWitt, C.M., Friedman, A., Donnelly, J.J. and Liu, M.A. Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines. Vaccine 1994, 12, 1541-1544
3. Donnelly, J.J., Friedman, A. and Martinez, D. et al. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. Nat. Med. 1995, 1, 583-587
4. Robinson, H.L., Hunt, L.A. and Webster, R.G. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 1993, 9, 957-960
5. Manickan, E., Rouse, R.J.D., Yu, Z., Wire, W.S. and Rouse, B.T. Genetic immunization against herpes simplex virus: protection is mediated by CD4+ T lymphocytes. J. Immunol. 1995, 155, 259-265
6. Xiang, Z.G., Spitalnik, S.L., Tran, M., Wunner, W.H., Cheng, J. and Ertl, H.C. Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. Virology 1994, 199, 132-140
7. Donnelly, J.J., Martinez, D., Jansen, K., Ellis, R.W., Montgomery, D.L. and Liu, M.A. Protection against papilloma virus with a polynucleotide vaccine. J. Infect. Dis. 1996, 713, 314-320
8. Koup, R.A., Safrit, J.T. and Cao, Y. et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 1994, 68, 4650-4655
9. Klein, M.R., van Baalen, C.A. and Holwerda, A.M. et al. Kinetics of gag-specific cytotoxic T lymphocyte responses during a clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics. J. Exp. Med. 1995, 181, 1365-1372
10. Almond, N., Kent, K., Cranage, M., Rud, E., Clarke, B. and Stott, E.J. Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. The Lancet 1995, 345, 1342-1344
11. Shiver, J.W., Perry, H.C., Davies, M.E., Freed, D.C. and Liu, M.A. Cytotoxic T lymphocyte and helper T cell responses following HIV polynucleotide vaccination. Ann. NY Acad. Sci. 1995, 772, 198-208
12. Shiver, J.W., Davies, M.E., Perry, H.C., Freed, D.C. and Liu, M.A. Humoral and cellular immunities elicited by HIV-1 DNA vaccination. J. Pharm. Sci. 1996, 85, 1317-1324