SAR studies on the potent and selective muscarinic antagonist 2- ethylthio-2,2-diphenylacetic acid N,N-diethylaminoethyl ester

Archiv der Pharmazie

Volumn 330, Issue 5, 1997, Pages 122-128

  Scapecchi, Serena ^a   Angeli, Piero ^b   Dei, Silvia ^a   Ghelardini, Carla ^a   Gualtieri, Fulvio ^a   Marucci, Gabriella ^b   Paparelli, Fiorella ^b   Romanelli, M Novella ^a   Teodori, Elisabetta ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Alzheimer's disease; M2 selectivity; Muscarinic antagonists

Indexed keywords

2 ETHYLTHIO 2,2 DIPHENYLACETIC ACID N,N DIETHYLAMINOETHYL ESTER; DIPHENYLACETIC ACID; MUSCARINIC RECEPTOR BLOCKING AGENT; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CHEMICAL MODIFICATION; DOSE RESPONSE; DRUG PENETRATION; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; BLOOD-BRAIN BARRIER; GUINEA PIGS; MALE; MICE; MUSCARINIC ANTAGONISTS; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030754059     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19973300503     Document Type: Article

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