Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells

Journal of Lipid Research

Volumn 38, Issue 7, 1997, Pages 1299-1307

  Risé, Patrizia ^a   Colombo, Claudio ^a   Galli, Claudio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Fatty acid desaturation and elongation; Isoprenoids; Lipid synthesis from glycerol and acetate; Mevalonate; Simvastatin; THP 1 cells

Indexed keywords

CHOLESTEROL; FARNESOL; GERANYLGERANIOL; GLYCEROLIPID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ICOSAPENTAENOIC ACID; ISOPRENOID; LINOLEIC ACID; LIPID; LONG CHAIN FATTY ACID; MEVALONIC ACID; POLYUNSATURATED FATTY ACID; SIMVASTATIN; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL SYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; FATTY ACID DESATURATION; FATTY ACID METABOLISM; HUMAN; HUMAN CELL; LIPOGENESIS; PRIORITY JOURNAL;

ACETATES; ANTILIPEMIC AGENTS; CELL LINE; CHOLESTEROL; DITERPENES; ENZYME INHIBITORS; ESTERIFICATION; FATTY ACIDS, UNSATURATED; GLYCEROL; GLYCOLIPIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LINOLEIC ACID; LINOLEIC ACIDS; LIPIDS; LOVASTATIN; MEVALONIC ACID; MONOCYTES; SIMVASTATIN;

EID: 0030753142     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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