Striatal uptake of I-123-β-CIT and I-123-IBZM in patients with extrapyramidal symptoms;Striatale Aufnahme von I-123-β-CIT und I-123-IBZM bei Patienten mit extrapyramidaler Symptomatik

NuklearMedizin

Volumn 36, Issue 5, 1997, Pages 167-172

  Bettin, Simone ^a   Kämpfer, Ingrid ^a   Seese, Anita ^a   Schäfer, Angelika ^a   Reuter, M ^a   Loßner J ^a   Dietrich, J ^a   Wagner, A ^a   Knapp, W H ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

D2 receptors; dopamine transporter; I 123 IBZM; I 123 CIT; Parkinson's disease

Indexed keywords

BETA CIT I 123; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; IBZM I 123; IODINE 123; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CORPUS STRIATUM; FEMALE; HUMAN; MALE; PARKINSON DISEASE; PARKINSONISM; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; WILSON DISEASE;

EID: 0030753058     PISSN: 00295566     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1629787     Document Type: Article

References (22)

1. Angelberger P, Kvaternik H, Portner R et al. Optimized preparation of the dopaminergic receptor ligands I-123-epidepride and 1-123-CIT. Eur J Nucl Med 1994; 1: 16.
2. Bjorklund A, Lindvall O. Dopaminecontaining systems in the CNS. In: Handbook of Chemical Neuroanatomy, Vol. 2: Classical Transmitters in the CNS, Part I. Bjorklund A, Hökfelt T (eds.). Amsterdam: Elsevier Science Publishers 1984.
3. Brandt T, Dichganns J, Diener H CH et al. Therapie und Verlauf neurologischer Erkrankungen. Stuttgart: Kohlhammer 1994; 927-64.
4. Brucke T, Kornhuber J, Angelberger P et al. SPECT imaging of dopamine and serotonine transporters with (I-123) beta-CIT. Binding kinetics in the human brain. J Neural Transm Gen Sect 1993; 94 (2): 137-46.
5. Brücke T, Wenger S, Asenbaum S et al. Dopamine D2 receptor imaging and measurement with SPECT. Adv Neurol 1993; 60: 494-500.
6. Coenen HH, Dutschka K, Müller S et al. Metabolite des I-123-β-CIT interferieren nicht mit seiner zerebralen Aufnahme. Nuklearmedizin 1995; 35: A 140.
7. Costa DC, Verhoeff NPLG, Cullum ID et al. In vivo characterisation of 3-iodo-6-methoxybenzamide I-123 in humans. Eur J Nucl Med 1990; 16: 813-6.
8. van Dyck CH, Seibyl JP, Malison RT et al. Age-related decline in striatal dopamine transporter binding with iodine-123-beta-CIT-SPECT. J Nucl Med 1995; 36 (7): 1175-81.
9. Hentschel F. Bildgebende Diagnostik bei dementiellen Erkrankungen. Klin Neuroradiologie, Band 4, 1994; 131-46.
10. Innis R, Seibyl J, Scanley B et al. Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson's disease. Proc Nat Acad Sci USA 1993; 90: 11965-9.
11. Innis R. Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease. Eur J Nucl Med 1994; 21: 1-5.
12. Kuikka J, Bergström K, Vanninen E et al. Initial experience with single-photon emission tomography using iodine-123-labelled 2β-carbomethoxy-3β-(4-iodophenyl) tropane. Eur J Nucl Med 1993; 20: 783-6.
13. Kuikka J, Bergstrom K, Vanninen E et al. The dosimetry of iodine-123 labelled 2β-carbomethoxy-3β-(4-iodophenyl) tropane. Eur J Nucl Med 1994; 21: 53-6.
14. Kuikka J, Tiihonen J, Bergström K et al. Imaging of serotonine and dopamine transporters in the living human brain. Eur J Nucl Med 1995; 22: 346-50.
15. Oertel W, Tatsch K, Schwarz J et al. Decrease of D2 receptors indicated by I-123-iodobenzamide single-photon emission computed tomography relates to neurological deficit in treated Wilson's disease. Ann Neurol 1992; 32: 743-8
16. Riederer P et al. Neuro-Psychopharmaka. Band 4. Berlin: Springer-Verlag 1992; 186.
17. Schwarz J, Tatsch K, Arnold G et al.: I-123-iodobenzamide-SPECT predicts dopaminergic responsiveness in patients with de novo parkinsonism. Neurology 1992; 42: 556-61.
18. Schwarz J, Tatsch K, Oertel WH et al. IBZM-SPECT for dopamine D2 receptor imaging in patients with Wilson's disease: an indicator of striatal damage and its functional recovery following therapy. Z Gastroenterol 1995; 33: 489.
19. Snow B, Bhatt M, Martin W et al. The nigrostriatal dopaminergic pathway in Wilson's disease studied with positron emission tomography. J Neurol Neurosurg Psychiatry 1991; 54 (1): 12-7.
20. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. Stuttgart: Thieme 1988; 94-9.
21. Tatsch K, Schwarz J, Kirsch CM et al. ZNSSPECT: Rezeptorszintigraphie mit I-123-IBZM und I-123-Iomazenil. Der Nuklearmediziner 1993; 16: 143-50.
22. Zea-Ponce Y, Baldwin RM, Laruelle M et al. Simplified multidose preparation of iodine123-β-CIT: A marker for dopamine transporters. J Nucl Med 1995; 36: 525-9.