-
1
-
-
0026561245
-
The p53 tumor-suppressor gene
-
Levine AJ: The p53 tumor-suppressor gene. N Engl J Med 326: 1350-1352, 1992.
-
(1992)
N Engl J Med
, vol.326
, pp. 1350-1352
-
-
Levine, A.J.1
-
4
-
-
0029919634
-
Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation
-
Hollstein M, Shomer B, Greenblatt M, Soussi T, Hovig E, Montesano R and Harris CC: Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res 24: 141-146, 1996.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 141-146
-
-
Hollstein, M.1
Shomer, B.2
Greenblatt, M.3
Soussi, T.4
Hovig, E.5
Montesano, R.6
Harris, C.C.7
-
5
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sorlie T, Hovig E, Smith-Sorensen B, Montesano R and Harris CC: Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 22: 3551-3555, 1994.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
Soussi, T.4
Fuchs, R.5
Sorlie, T.6
Hovig, E.7
Smith-Sorensen, B.8
Montesano, R.9
Harris, C.C.10
-
6
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC, Fraumeni JFJ, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA and Friend SF: Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250: 1233-1238, 1990.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, J.F.J.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.F.11
-
7
-
-
0026530299
-
Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms
-
Malkin D, Jolly KW, Barbier N, Look AT, Friend SH, Gebhardt MC, Andersen TI, Borresen AL, Li FP, Garber J, et al: Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. N Engl J Med 326: 1309-1315, 1992.
-
(1992)
N Engl J Med
, vol.326
, pp. 1309-1315
-
-
Malkin, D.1
Jolly, K.W.2
Barbier, N.3
Look, A.T.4
Friend, S.H.5
Gebhardt, M.C.6
Andersen, T.I.7
Borresen, A.L.8
Li, F.P.9
Garber, J.10
-
8
-
-
0025648762
-
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
-
Srivastava S, Zou ZQ, Pirollo K, Blattner W and Chang EH: Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 348: 747-749, 1990.
-
(1990)
Nature
, vol.348
, pp. 747-749
-
-
Srivastava, S.1
Zou, Z.Q.2
Pirollo, K.3
Blattner, W.4
Chang, E.H.5
-
9
-
-
0027327989
-
Several mutant p53 proteins detected in cancer-prone families with Li-Fraumeni syndrome exhibit transdominant effects on the biochemical properties of the wild-type p53
-
Srivastava S, Wang S, Tong YA, Pirollo K and Chang EH: Several mutant p53 proteins detected in cancer-prone families with Li-Fraumeni syndrome exhibit transdominant effects on the biochemical properties of the wild-type p53. Oncogene 8: 2449-2456, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 2449-2456
-
-
Srivastava, S.1
Wang, S.2
Tong, Y.A.3
Pirollo, K.4
Chang, E.H.5
-
10
-
-
0028350959
-
Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma
-
McIntyre JF, Smith-Sorensen B, Friend SH, Kassell J, Borresen AL, Yan YX, Russo C, Sato J, Barbier N, Miser J, Malkin D and Gebhardt MC: Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma. J Clin Oncol 12: 925-930, 1994.
-
(1994)
J Clin Oncol
, vol.12
, pp. 925-930
-
-
McIntyre, J.F.1
Smith-Sorensen, B.2
Friend, S.H.3
Kassell, J.4
Borresen, A.L.5
Yan, Y.X.6
Russo, C.7
Sato, J.8
Barbier, N.9
Miser, J.10
Malkin, D.11
Gebhardt, M.C.12
-
11
-
-
0026525839
-
Prevalence and spectrum of germline mutations of the p53 gene among patients with sarcoma
-
Toguchida J, Yamaguchi T, Dayton SH, Beauchamp RL, Herrera GE, Ishizaki K, Yamamuro T, Meyers PA, Little JB, Sasaki MS, et al: Prevalence and spectrum of germline mutations of the p53 gene among patients with sarcoma. N Engl J Med 326: 1301-1308, 1992.
-
(1992)
N Engl J Med
, vol.326
, pp. 1301-1308
-
-
Toguchida, J.1
Yamaguchi, T.2
Dayton, S.H.3
Beauchamp, R.L.4
Herrera, G.E.5
Ishizaki, K.6
Yamamuro, T.7
Meyers, P.A.8
Little, J.B.9
Sasaki, M.S.10
-
12
-
-
0026480293
-
Cancer risks from germline p53 mutations
-
Frebourg T and Friend SH: Cancer risks from germline p53 mutations. J Clin Invest 90: 1637-1641, 1992.
-
(1992)
J Clin Invest
, vol.90
, pp. 1637-1641
-
-
Frebourg, T.1
Friend, S.H.2
-
13
-
-
0025790531
-
p53 germline mutations in Li-Fraumeni syndrome
-
13: Santibanez-Koref MF, Birch JM, Hartley AL, Jones PH, Craft AW, Eden T, Crowther D, Kelsey AM and Harris M: p53 germline mutations in Li-Fraumeni syndrome. Lancet 338: 1490-1491, 1991.
-
(1991)
Lancet
, vol.338
, pp. 1490-1491
-
-
Santibanez-Koref, M.F.1
Birch, J.M.2
Hartley, A.L.3
Jones, P.H.4
Craft, A.W.5
Eden, T.6
Crowther, D.7
Kelsey, A.M.8
Harris, M.9
-
14
-
-
0027489384
-
Clinical implications of the p53 tumor suppressor gene
-
Harris CC and Hollstein M: Clinical implications of the p53 tumor suppressor gene. N Engl J Med 329: 1318-1327, 1993.
-
(1993)
N Engl J Med
, vol.329
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
16
-
-
0014587529
-
Soft-tissue sarcomas, breast cancer, and other neoplasms: A familial syndrome?
-
Li FP and Fraumeni JF: Soft-tissue sarcomas, breast cancer, and other neoplasms: a familial syndrome? Ann Intern Med 71: 747-752, 1969.
-
(1969)
Ann Intern Med
, vol.71
, pp. 747-752
-
-
Li, F.P.1
Fraumeni, J.F.2
-
17
-
-
0023715595
-
A cancer family syndrome in twenty-four kindreds
-
Li FP, Fraumeni JF, Mulvihill JJ, Blattner WA, Dreyfus MG, Tucker MA and Miller RW: A cancer family syndrome in twenty-four kindreds. Cancer Res 48: 5358-5362, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 5358-5362
-
-
Li, F.P.1
Fraumeni, J.F.2
Mulvihill, J.J.3
Blattner, W.A.4
Dreyfus, M.G.5
Tucker, M.A.6
Miller, R.W.7
-
18
-
-
0026871286
-
The role of tumour suppressor genes in familial cancer
-
Malkin D and Friend SH: The role of tumour suppressor genes in familial cancer. Semin Cancer Biol 3: 121-130, 1992.
-
(1992)
Semin Cancer Biol
, vol.3
, pp. 121-130
-
-
Malkin, D.1
Friend, S.H.2
-
19
-
-
0028095433
-
Familial cancer syndromes and clusters
-
Birch JM: Familial cancer syndromes and clusters. Br Med Bull 50: 624-639, 1994.
-
(1994)
Br Med Bull
, vol.50
, pp. 624-639
-
-
Birch, J.M.1
-
20
-
-
0028149189
-
Li-Fraumeni syndrome
-
Birch JM: Li-Fraumeni syndrome. Eur J Cancer 30A: 1935-1941, 1994.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1935-1941
-
-
Birch, J.M.1
-
21
-
-
0027223409
-
Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: Molecular and immunohistochemical findings
-
Eeles RA, Warren W, Knee G, Bartek J, Averill D, Stratton MR, Blake PR, Tait DM, Lane DP, Easton DF, et al: Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings. Oncogene 8: 1269-1276, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 1269-1276
-
-
Eeles, R.A.1
Warren, W.2
Knee, G.3
Bartek, J.4
Averill, D.5
Stratton, M.R.6
Blake, P.R.7
Tait, D.M.8
Lane, D.P.9
Easton, D.F.10
-
22
-
-
0027191248
-
A novel germline p53 splicing mutation in a pediatric patient with a second malignant neoplasm
-
Felix CA, Strauss EA, D'Amico D, Tsokos M, Winter S, Mitsudomi T, Nau MM, Brown DL, Leahey AM, Horowitz ME, et al: A novel germline p53 splicing mutation in a pediatric patient with a second malignant neoplasm. Oncogene 8: 1203-1210, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 1203-1210
-
-
Felix, C.A.1
Strauss, E.A.2
D'Amico, D.3
Tsokos, M.4
Winter, S.5
Mitsudomi, T.6
Nau, M.M.7
Brown, D.L.8
Leahey, A.M.9
Horowitz, M.E.10
-
23
-
-
0028566388
-
A de novo p53 germline mutation affecting codon 151 in a six year old child with multiple tumors
-
Gutierrez MI, Bhatia KG, Barreiro C, Spangler G, Schvartzmann E, Muriel FS and Magrath IT: A de novo p53 germline mutation affecting codon 151 in a six year old child with multiple tumors. Hum Molec Genet 3: 2247-2248, 1994.
-
(1994)
Hum Molec Genet
, vol.3
, pp. 2247-2248
-
-
Gutierrez, M.I.1
Bhatia, K.G.2
Barreiro, C.3
Spangler, G.4
Schvartzmann, E.5
Muriel, F.S.6
Magrath, I.T.7
-
25
-
-
34547384728
-
A germline missense mutation in exon 10 of the human p53 gene
-
In press
-
Luca JW, Strong LC and Hansen MF: A germline missense mutation in exon 10 of the human p53 gene. Hum Mut (In press).
-
Hum Mut
-
-
Luca, J.W.1
Strong, L.C.2
Hansen, M.F.3
-
26
-
-
0028958465
-
Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma
-
Diller L, Sexsmith E, Gottlieb A, Li FP and Malkin D: Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma. J Clin Invest 95: 1606-1611, 1995.
-
(1995)
J Clin Invest
, vol.95
, pp. 1606-1611
-
-
Diller, L.1
Sexsmith, E.2
Gottlieb, A.3
Li, F.P.4
Malkin, D.5
-
27
-
-
0027985697
-
High frequency of germline p53 mutations in childhood adrenocortical cancer
-
Wagner J, Portwine C, Rabin K, Leclerc JM, Narod SA and Malkin D: High frequency of germline p53 mutations in childhood adrenocortical cancer. J Natl Cancer Inst 86: 1707-1710, 1994.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1707-1710
-
-
Wagner, J.1
Portwine, C.2
Rabin, K.3
Leclerc, J.M.4
Narod, S.A.5
Malkin, D.6
-
28
-
-
0028062058
-
Novel germline mutation of the p53 tumor suppressor gene in a child with incidentally discovered adrenal cortical carcinoma
-
Grayson GH, Moore S, Schneider BG, Saldivar V and Hensel CH: Novel germline mutation of the p53 tumor suppressor gene in a child with incidentally discovered adrenal cortical carcinoma. Am J Pediatric Hematol-Oncol 16: 341-347, 1994.
-
(1994)
Am J Pediatric Hematol-Oncol
, vol.16
, pp. 341-347
-
-
Grayson, G.H.1
Moore, S.2
Schneider, B.G.3
Saldivar, V.4
Hensel, C.H.5
-
29
-
-
0028221553
-
Germline p53 gene mutations in subsets of glioma patients
-
Kyritsis AP, Bondy ML, Xiao M, Berman EL, Cunningham JE, Lee PS, Levin VA and Saya H: Germline p53 gene mutations in subsets of glioma patients. J Natl Cancer Inst 86: 344-349, 1994.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 344-349
-
-
Kyritsis, A.P.1
Bondy, M.L.2
Xiao, M.3
Berman, E.L.4
Cunningham, J.E.5
Lee, P.S.6
Levin, V.A.7
Saya, H.8
-
30
-
-
0029122414
-
Constitutional p53 mutations associated with brain tumors in young adults
-
Chen P, Iavarone A, Fick J, Edwards M, Prados M and Israel MA: Constitutional p53 mutations associated with brain tumors in young adults. Cancer Genet Cytogenet 82: 106-115, 1995.
-
(1995)
Cancer Genet Cytogenet
, vol.82
, pp. 106-115
-
-
Chen, P.1
Iavarone, A.2
Fick, J.3
Edwards, M.4
Prados, M.5
Israel, M.A.6
-
31
-
-
0026636975
-
Inherited p53 gene mutations in breast cancer
-
Sidransky D, Tokino T, Helzlsouer K, Zehnbauer B, Rausch G, Shelton B, Prestigiacomo L, Vogelstein B and Davidson N: Inherited p53 gene mutations in breast cancer. Cancer Res 52: 2984-2986, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2984-2986
-
-
Sidransky, D.1
Tokino, T.2
Helzlsouer, K.3
Zehnbauer, B.4
Rausch, G.5
Shelton, B.6
Prestigiacomo, L.7
Vogelstein, B.8
Davidson, N.9
-
32
-
-
0026785914
-
Germline mutations in the p53 tumour suppressor gene: Scientific, clinical and ethical challenges
-
Birch JM: Germline mutations in the p53 tumour suppressor gene: scientific, clinical and ethical challenges. Br J Cancer 66: 424-426, 1992.
-
(1992)
Br J Cancer
, vol.66
, pp. 424-426
-
-
Birch, J.M.1
-
33
-
-
0027252913
-
Predictive testing for germline mutations in the p53 gene: Are all the questions answered?
-
Eeles RA: Predictive testing for germline mutations in the p53 gene: are all the questions answered? Eur J Cancer 29A: 1361-1365, 1993.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 1361-1365
-
-
Eeles, R.A.1
-
34
-
-
0020518746
-
Expression of recessive alleles by chromosomal mechanisms in retino-blastoma
-
Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie BL, Murphree AL, Strong LC and White RL: Expression of recessive alleles by chromosomal mechanisms in retino-blastoma. Nature 305: 779-784, 1983.
-
(1983)
Nature
, vol.305
, pp. 779-784
-
-
Cavenee, W.K.1
Dryja, T.P.2
Phillips, R.A.3
Benedict, W.F.4
Godbout, R.5
Gallie, B.L.6
Murphree, A.L.7
Strong, L.C.8
White, R.L.9
-
35
-
-
0023584218
-
Genetics of cancer predisposition
-
Hansen MF and Cavenee WK: Genetics of cancer predisposition. Cancer Res 47: 5518-5527, 1987.
-
(1987)
Cancer Res
, vol.47
, pp. 5518-5527
-
-
Hansen, M.F.1
Cavenee, W.K.2
-
37
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD and Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215, 1988.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
38
-
-
0025834677
-
Detection of p53 gene mutations in human brain tumors by single-strand conformation polymorphism analysis of polymerase chain reaction products
-
Mashiyama S, Murakami Y, Yoshimoto T, Sekiya T and Hayashi K: Detection of p53 gene mutations in human brain tumors by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 6: 1313-1318, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 1313-1318
-
-
Mashiyama, S.1
Murakami, Y.2
Yoshimoto, T.3
Sekiya, T.4
Hayashi, K.5
-
39
-
-
0024595101
-
Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
-
Orita M, Iwahana H, Kanazawa H, Hayashi K and Sekiya T: Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 86: 2766-2770, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2766-2770
-
-
Orita, M.1
Iwahana, H.2
Kanazawa, H.3
Hayashi, K.4
Sekiya, T.5
-
40
-
-
0024756969
-
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
-
Orita M, Suzuki Y, Sekiya T and Hayashi K: Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5: 874-879, 1989.
-
(1989)
Genomics
, vol.5
, pp. 874-879
-
-
Orita, M.1
Suzuki, Y.2
Sekiya, T.3
Hayashi, K.4
-
41
-
-
0027405940
-
Screening for germ line p53 mutations in children with malignant tumors and a family history of cancer
-
Brugieres L, Gardes M, Moutou C, Chompret A, Meresse V, Martin A, Poisson N, Flamant F, Bonaiti-Pellie C, Lemerle J, et al: Screening for germ line p53 mutations in children with malignant tumors and a family history of cancer. Cancer Res 53: 452-455, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 452-455
-
-
Brugieres, L.1
Gardes, M.2
Moutou, C.3
Chompret, A.4
Meresse, V.5
Martin, A.6
Poisson, N.7
Flamant, F.8
Bonaiti-Pellie, C.9
Lemerle, J.10
-
42
-
-
0028220688
-
Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families
-
Birch JM, Hartley AL, Tricker KJ, Prosser J, Condie A, Kelsey AM, Harris M, Jones PH, Binchy A, Crowther D, Craft AW, Eden OB, Evans DGR, Thompson E, Mann JR, Martin J, Mitchell ELD and Santibanez-Koref MF: Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families. Cancer Res 54: 1298-1304, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1298-1304
-
-
Birch, J.M.1
Hartley, A.L.2
Tricker, K.J.3
Prosser, J.4
Condie, A.5
Kelsey, A.M.6
Harris, M.7
Jones, P.H.8
Binchy, A.9
Crowther, D.10
Craft, A.W.11
Eden, O.B.12
Evans, D.G.R.13
Thompson, E.14
Mann, J.R.15
Martin, J.16
Mitchell, E.L.D.17
Santibanez-Koref, M.F.18
-
43
-
-
0028938301
-
Heterogeneity in Li-Fraumeni families: P53 mutation analysis and immunohistochemical staining
-
MacGeoch C, Turner G, Bobrow LG, Barnes DM, Bishop DT and Spurr NK: Heterogeneity in Li-Fraumeni families: p53 mutation analysis and immunohistochemical staining. J Med Genet 32: 186-190, 1995.
-
(1995)
J Med Genet
, vol.32
, pp. 186-190
-
-
MacGeoch, C.1
Turner, G.2
Bobrow, L.G.3
Barnes, D.M.4
Bishop, D.T.5
Spurr, N.K.6
-
44
-
-
0015043748
-
Mutation and cancer: A statistical study of retinoblastoma
-
Knudson AG: Mutation and cancer: a statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820-823, 1971.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
45
-
-
0039712065
-
Mutation and childhood cancer: A probabilistic model for the incidence of retinoblastoma
-
Knudson AG, Hethcote HW and Brown BW: Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma. Proc Natl Acad Sci USA 72: 5116-5120, 1975.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 5116-5120
-
-
Knudson, A.G.1
Hethcote, H.W.2
Brown, B.W.3
-
46
-
-
0015295131
-
Mutation and cancer: A model for Wilms' tumor of the kidney
-
Knudson AG and Strong LC: Mutation and cancer: a model for Wilms' tumor of the kidney. J Natl Cancer Inst 48: 313-333, 1972.
-
(1972)
J Natl Cancer Inst
, vol.48
, pp. 313-333
-
-
Knudson, A.G.1
Strong, L.C.2
-
47
-
-
0017161982
-
Genetics and the etiology of childhood cancer
-
Knudson AG: Genetics and the etiology of childhood cancer. Pediatr Res 10: 513-517, 1976.
-
(1976)
Pediatr Res
, vol.10
, pp. 513-517
-
-
Knudson, A.G.1
|