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Volumn 52, Issue 6, 1997, Pages 602-612

New routes and formulations for allergen-specific immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; VACCINE;

EID: 0030752954     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1997.tb01038.x     Document Type: Review
Times cited : (23)

References (72)
  • 1
    • 0002123367 scopus 로고
    • The immunizing cure for hay fever
    • Curtis H. The immunizing cure for hay fever. N Y Med J 1900;74:16.
    • (1900) N Y Med J , vol.74 , pp. 16
    • Curtis, H.1
  • 2
    • 50249230114 scopus 로고
    • Prophylactic inoculation against hay fever
    • Noon L. Prophylactic inoculation against hay fever. Lancet 1911:1:1572-3.
    • (1911) Lancet , vol.1 , pp. 1572-1573
    • Noon, L.1
  • 3
    • 0001686164 scopus 로고
    • A double-blind study of the effectiveness and specificity of injection therapy in ragweed hay fever
    • Lowell FC, Franklin B. A double-blind study of the effectiveness and specificity of injection therapy in ragweed hay fever. N Engl J Med 1975;273:675-9.
    • (1975) N Engl J Med , vol.273 , pp. 675-679
    • Lowell, F.C.1    Franklin, B.2
  • 5
    • 0019777915 scopus 로고
    • Immunotherapy of atopic disorders. Present state of the art and future perspectives
    • Ziegler RS, Schatz M. Immunotherapy of atopic disorders. Present state of the art and future perspectives. Pediatr Clin North Am 1981;65:987-1012.
    • (1981) Pediatr Clin North Am , vol.65 , pp. 987-1012
    • Ziegler, R.S.1    Schatz, M.2
  • 6
    • 84973587700 scopus 로고
    • CSM update: desensitising vaccines. BMJ 1986;293:948.
    • (1986) BMJ , vol.293 , pp. 948
  • 7
    • 0001461109 scopus 로고
    • In vitro studies of human ragweed allergy: Changes in cellular and humoral activity associated with specific desensitization
    • Lichtenstein LM, Norman PS, Winkenwerder WL. In vitro studies of human ragweed allergy: changes in cellular and humoral activity associated with specific desensitization. J Clin Invest 1966;45:1126-36.
    • (1966) J Clin Invest , vol.45 , pp. 1126-1136
    • Lichtenstein, L.M.1    Norman, P.S.2    Winkenwerder, W.L.3
  • 8
    • 0014175692 scopus 로고
    • Identification of E-antibodies as a carrier of reaginic activity
    • Ishizaka K, Ishizaka T. Identification of E-antibodies as a carrier of reaginic activity. J Immunol 1967;99:1187-98.
    • (1967) J Immunol , vol.99 , pp. 1187-1198
    • Ishizaka, K.1    Ishizaka, T.2
  • 10
    • 84912700339 scopus 로고
    • Specific hyposensitisation
    • Buckle DR, Smith H, editors. London: Butterworths
    • Moran DM, Wheeler AW. Specific hyposensitisation. In: Buckle DR, Smith H, editors. Development of anti-asthma drugs. London: Butterworths, 1977:349-89.
    • (1977) Development of Anti-asthma Drugs. , pp. 349-389
    • Moran, D.M.1    Wheeler, A.W.2
  • 12
    • 0025923025 scopus 로고
    • Human Th1 and Th2 subsets: Doubt no more
    • Romagnani S. Human Th1 and Th2 subsets: doubt no more. Immunol Today 1991;12:256-7.
    • (1991) Immunol Today , vol.12 , pp. 256-257
    • Romagnani, S.1
  • 13
    • 34247569209 scopus 로고
    • Serological evidence of immunity with co-existing sensitisation in a type of human allergy (hay fever)
    • Cook RA, Barnard JH, Hebald S, Stull A. Serological evidence of immunity with co-existing sensitisation in a type of human allergy (hay fever). J Exp Med 1935;62: 733-50.
    • (1935) J Exp Med , vol.62 , pp. 733-750
    • Cook, R.A.1    Barnard, J.H.2    Hebald, S.3    Stull, A.4
  • 14
    • 0018770332 scopus 로고
    • Local production of IgG, IgA and IgE antibodies in grass pollen hay fever
    • Platts-Mills TAE. Local production of IgG, IgA and IgE antibodies in grass pollen hay fever. J Immunol 1979;122:2218-25.
    • (1979) J Immunol , vol.122 , pp. 2218-2225
    • Platts-Mills, T.A.E.1
  • 17
    • 0018152043 scopus 로고
    • Allergen-specific IgE and IgG antibodies in pollen allergic children given immunotherapy for 2 to 6 years
    • Foucard T, Johansson SGO. Allergen-specific IgE and IgG antibodies in pollen allergic children given immunotherapy for 2 to 6 years. Clin Allergy 1978;8:249-59.
    • (1978) Clin Allergy , vol.8 , pp. 249-259
    • Foucard, T.1    Johansson, S.G.O.2
  • 18
    • 0017601371 scopus 로고
    • Studies of perennial ragweed immunotherapy, associated changes in cellular responsiveness, total serum antigen-binding capacity and specific IgE antibody concentrations
    • Irons JS, Pruzansky JJ, Patterson R, Zeiss CR. Studies of perennial ragweed immunotherapy, associated changes in cellular responsiveness, total serum antigen-binding capacity and specific IgE antibody concentrations. J Allergy Clin Immunol 1977;59:190-9.
    • (1977) J Allergy Clin Immunol , vol.59 , pp. 190-199
    • Irons, J.S.1    Pruzansky, J.J.2    Patterson, R.3    Zeiss, C.R.4
  • 19
    • 85036490555 scopus 로고
    • Specific alterations in sensitivity of leukocytes of treated allergic patients
    • Feb: (Abstract 60).
    • Pruzansky JJ, Golbert TM, Patterson R. Specific alterations in sensitivity of leukocytes of treated allergic patients. J Allergy 1968;Feb:114(Abstract 60).
    • (1968) J Allergy , pp. 114
    • Pruzansky, J.J.1    Golbert, T.M.2    Patterson, R.3
  • 20
    • 0015387221 scopus 로고
    • Non-specific passive desensitisation: A brief review
    • Swineford O Jr. Non-specific passive desensitisation: a brief review. Ann Allergy 1972;30:464-72.
    • (1972) Ann Allergy , vol.30 , pp. 464-472
    • Swineford Jr., O.1
  • 21
    • 0026102389 scopus 로고
    • Hyposensitisation therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria)
    • Bonifazi F, Antonicelli L, Bilò MB, et al. Hyposensitisation therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria). J Invest Allergol Clin Immunol 1991;1:37-44.
    • (1991) J Invest Allergol Clin Immunol , vol.1 , pp. 37-44
    • Bonifazi, F.1    Antonicelli, L.2    Bilò, M.B.3
  • 22
    • 0018875627 scopus 로고
    • Generation of antigen-specific suppressor cells during allergy desensitisation
    • Rocklin RE, Sheffer AL. Generation of antigen-specific suppressor cells during allergy desensitisation. N Engl J Med 1980;302:1213-19.
    • (1980) N Engl J Med , vol.302 , pp. 1213-1219
    • Rocklin, R.E.1    Sheffer, A.L.2
  • 24
    • 0028395905 scopus 로고
    • Novel approaches in immunotherapy
    • St Remy J-MR. Novel approaches in immunotherapy. Clin Rev Allergy 1994;12:23-42.
    • (1994) Clin Rev Allergy , vol.12 , pp. 23-42
    • St Remy, J.-M.R.1
  • 25
    • 0024370621 scopus 로고
    • Suppression of the late asthmatic reaction by hyposensitisation in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus)
    • van Bever HF, Stevens WJ. Suppression of the late asthmatic reaction by hyposensitisation in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus). Clin Exp Allergy 1989;19:399-404.
    • (1989) Clin Exp Allergy , vol.19 , pp. 399-404
    • Van Bever, H.F.1    Stevens, W.J.2
  • 26
    • 0025913662 scopus 로고
    • Immunotherapy decreases antigen-induced eosinophil migration into the nasal cavity
    • Furin MJ, Norman PS, Creticos PS, et al. Immunotherapy decreases antigen-induced eosinophil migration into the nasal cavity. J Allergy Clin Immunol 1991;88:27-32.
    • (1991) J Allergy Clin Immunol , vol.88 , pp. 27-32
    • Furin, M.J.1    Norman, P.S.2    Creticos, P.S.3
  • 27
    • 0026727804 scopus 로고
    • Advances in specific immunotherapy
    • Bousquet J, Michel FB. Advances in specific immunotherapy. Clin Exp Allergy 1992;22:889-96.
    • (1992) Clin Exp Allergy , vol.22 , pp. 889-896
    • Bousquet, J.1    Michel, F.B.2
  • 28
    • 0028400530 scopus 로고
    • Modulation of allergen-specific antibody responses by T-cell peptide vaccines(s)
    • Mohapatra SS. Modulation of allergen-specific antibody responses by T-cell peptide vaccines(s). Clin Rev Allergy 1994;12:3-21.
    • (1994) Clin Rev Allergy , vol.12 , pp. 3-21
    • Mohapatra, S.S.1
  • 29
    • 0026616876 scopus 로고
    • Induction of Th1 and Th2 responses: A key role for the "natural" immune response
    • Romagnani S. Induction of Th1 and Th2 responses: a key role for the "natural" immune response. Immunol Today 1992;13:379-81.
    • (1992) Immunol Today , vol.13 , pp. 379-381
    • Romagnani, S.1
  • 30
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mossman TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mossman, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 32
    • 0029787026 scopus 로고    scopus 로고
    • Allergy vaccines. a review of developments
    • Hellman L, Carlsson M. Allergy vaccines. A review of developments. Clin Immunother 1996;6:130-42.
    • (1996) Clin Immunother , vol.6 , pp. 130-142
    • Hellman, L.1    Carlsson, M.2
  • 33
    • 0023818706 scopus 로고
    • Molecular and cellular biology of eosinophil differentiation factor (interleukin 5) and its effects on human and mouse B cells
    • Sanderson CJ, Campbell HD, Young IG. Molecular and cellular biology of eosinophil differentiation factor (interleukin 5) and its effects on human and mouse B cells. Immunol Rev 1988;102:29.
    • (1988) Immunol Rev , vol.102 , pp. 29
    • Sanderson, C.J.1    Campbell, H.D.2    Young, I.G.3
  • 35
    • 0028892985 scopus 로고
    • εR2/CD23 expression on peripheral B cells correlates with successful hyposensitisation in grass pollinosis
    • εR2/CD23 expression on peripheral B cells correlates with successful hyposensitisation in grass pollinosis. J Allergy Clin Immunol 1995;95:77-87.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 77-87
    • Jung, C.M.1    Prinz, J.C.2    Rieber, E.P.3    Ring, J.4
  • 36
    • 0028899083 scopus 로고
    • Allergens in rhinitis. B- And T-cell epitopes of allergen molecules
    • Schou C. Allergens in rhinitis. B- and T-cell epitopes of allergen molecules. Clin Exp Allergy 1995;25:10-14.
    • (1995) Clin Exp Allergy , vol.25 , pp. 10-14
    • Schou, C.1
  • 40
    • 0006870518 scopus 로고
    • Treatment of hay-fever with alum-precipitated pollen extract
    • Sledge RF. Treatment of hay-fever with alum-precipitated pollen extract. U S Naval Bull 1938;36:18-29.
    • (1938) U S Naval Bull , vol.36 , pp. 18-29
    • Sledge, R.F.1
  • 41
    • 0021920087 scopus 로고
    • Suppression of murine IgE responses with poly-(n-methylglycine)/ grass pollen extract conjugates using 4-(methylmercapto) phenyl-succinimidyl succinate as coupling reagent
    • Whittall N, Moran DM, Wheeler AW, Cottam GP. Suppression of murine IgE responses with poly-(n-methylglycine)/ grass pollen extract conjugates using 4-(methylmercapto) phenyl-succinimidyl succinate as coupling reagent. Int Arch Allergy Appl Immunol 1985;76:354-60.
    • (1985) Int Arch Allergy Appl Immunol , vol.76 , pp. 354-360
    • Whittall, N.1    Moran, D.M.2    Wheeler, A.W.3    Cottam, G.P.4
  • 43
    • 0026512067 scopus 로고
    • Liposomes for allergy immunotherapy
    • Walls AF. Liposomes for allergy immunotherapy. Clin Exp Allergy 1992;22:1-2.
    • (1992) Clin Exp Allergy , vol.22 , pp. 1-2
    • Walls, A.F.1
  • 45
    • 33847455489 scopus 로고
    • US patent 2019808
    • Carter EB. US patent 2019808: 1936.
    • (1936)
    • Carter, E.B.1
  • 46
    • 0014786859 scopus 로고
    • Studies on "Allergoids" prepared from naturally occurring allergens. I. Assay of allergenicity and antigenicity of formalinized rye group 1 component
    • Marsh DG, Lichtenstein LM, Campbell DH. Studies on "Allergoids" prepared from naturally occurring allergens. I. Assay of allergenicity and antigenicity of formalinized rye group 1 component. Immunology 1970;18:705-22.
    • (1970) Immunology , vol.18 , pp. 705-722
    • Marsh, D.G.1    Lichtenstein, L.M.2    Campbell, D.H.3
  • 47
    • 0025735025 scopus 로고
    • Standardisierung von Glutaraldehydemodifizierten Tyrosinadsorbieten Allergenextrakten
    • Overell BGO, Spackman DA, Wheeler AW, Pfeiffer P. Standardisierung von Glutaraldehydemodifizierten Tyrosinadsorbieten Allergenextrakten. Allergologie 1991;14: 110-15.
    • (1991) Allergologie , vol.14 , pp. 110-115
    • Overell, B.G.O.1    Spackman, D.A.2    Wheeler, A.W.3    Pfeiffer, P.4
  • 48
    • 0017078249 scopus 로고
    • Chemical modification of crude timothy grass pollen extract. I. Antigenicity and immunogenicity changes following amino group modification
    • Moran DM, Wheeler AW. Chemical modification of crude timothy grass pollen extract. I. Antigenicity and immunogenicity changes following amino group modification. Int Arch Allergy Appl Immunol 1976;50:693-708.
    • (1976) Int Arch Allergy Appl Immunol , vol.50 , pp. 693-708
    • Moran, D.M.1    Wheeler, A.W.2
  • 50
    • 0027258831 scopus 로고
    • Chemically modified antigen preferentially elicits induction of Thl-Iike cytokine synthesis patterns in vivo
    • Yang X, Gieni RS, Mossman TR. Chemically modified antigen preferentially elicits induction of Thl-Iike cytokine synthesis patterns in vivo. J Exp Med 1993;178:349-53.
    • (1993) J Exp Med , vol.178 , pp. 349-353
    • Yang, X.1    Gieni, R.S.2    Mossman, T.R.3
  • 51
    • 0025947122 scopus 로고
    • Antigen-specific inhibition of ongoing murine IgE responses. II. Inhibition of IgE responses by treatment with glutaraldehyde-modified allergens is paralleled by reciprocal increases in IgG2a synthesis
    • Hayglas KT, Stefura BP. Antigen-specific inhibition of ongoing murine IgE responses. II. Inhibition of IgE responses by treatment with glutaraldehyde-modified allergens is paralleled by reciprocal increases in IgG2a synthesis. J Immunol 1991;147:2455-60.
    • (1991) J Immunol , vol.147 , pp. 2455-2460
    • Hayglas, K.T.1    Stefura, B.P.2
  • 52
    • 0019372191 scopus 로고
    • Suppression of reaginic antibodies with modified allergens. III. Preparation of tolerogenic conjugates of common allergens with monomethoxy polyethylene glycols of different molecular weights by the mixed anhydride method
    • Wie SI, Wie CH, Lee WY, Filion LG, Sehon AH, Akerblom E. Suppression of reaginic antibodies with modified allergens. III. Preparation of tolerogenic conjugates of common allergens with monomethoxy polyethylene glycols of different molecular weights by the mixed anhydride method. Int Arch Allergy Appl Immunol 1981;64:84-9.
    • (1981) Int Arch Allergy Appl Immunol , vol.64 , pp. 84-89
    • Wie, S.I.1    Wie, C.H.2    Lee, W.Y.3    Filion, L.G.4    Sehon, A.H.5    Akerblom, E.6
  • 53
    • 0021958847 scopus 로고
    • Suppression of murine IgE responses with amino acid polymer/allergen conjugates. II. Suppressive activities in adjuvant-induced IgE responses
    • Wheeler AW, Henderson DC, Carman AJ, Moran DM. Suppression of murine IgE responses with amino acid polymer/allergen conjugates. II. Suppressive activities in adjuvant-induced IgE responses. Int Arch Allergy Appl Immunol 1985;76:361-8.
    • (1985) Int Arch Allergy Appl Immunol , vol.76 , pp. 361-368
    • Wheeler, A.W.1    Henderson, D.C.2    Carman, A.J.3    Moran, D.M.4
  • 55
    • 33847486506 scopus 로고    scopus 로고
    • Notes for guidance on allergen extracts. European Agency for Evaluation of Medicinal Products
    • Notes for guidance on allergen extracts. European Agency for Evaluation of Medicinal Products. Revised Version, 1996.
    • (1996) Revised Version
  • 57
    • 33847465491 scopus 로고
    • Allergen products for review. a technical guide
    • Allergen products for review. A technical guide. Paul Ehrlich Institute, 1992.
    • (1992) Paul Ehrlich Institute
  • 58
    • 33847445746 scopus 로고    scopus 로고
    • European Pharmacopeia. Allergen products
    • European Pharmacopeia. Allergen products. Producta allergenica. Jan 1997.
    • (1997) Producta Allergenica. Jan
  • 59
    • 0028962098 scopus 로고
    • A double blind, placebo-controlled trial of local nasal immunotherapy in allergic rhinitis to Parietaria pollen
    • D'Amato G, Lobefalo G, Liccardi G, Cazzola G, Cazzola M. A double blind, placebo-controlled trial of local nasal immunotherapy in allergic rhinitis to Parietaria pollen. Clin Exp Allergy 1995;25:141-8.
    • (1995) Clin Exp Allergy , vol.25 , pp. 141-148
    • D'Amato, G.1    Lobefalo, G.2    Liccardi, G.3    Cazzola, G.4    Cazzola, M.5
  • 60
    • 0017656968 scopus 로고
    • Oral hyposensitisation of children with pollinosis or house-dust asthma
    • Wortmann F. Oral hyposensitisation of children with pollinosis or house-dust asthma. Allergol Immunopathol (Madr) 1977;5:15-26.
    • (1977) Allergol Immunopathol (Madr) , vol.5 , pp. 15-26
    • Wortmann, F.1
  • 61
    • 0023213329 scopus 로고
    • Oral hyposensitisation with entericcoated allergens as extension therapy following a basic subcutaneous course of injections
    • Horak F, Wheeler AW. Oral hyposensitisation with entericcoated allergens as extension therapy following a basic subcutaneous course of injections. Int Arch Allergy Appl Immunol 1987;84:74-8.
    • (1987) Int Arch Allergy Appl Immunol , vol.84 , pp. 74-78
    • Horak, F.1    Wheeler, A.W.2
  • 63
    • 0028926175 scopus 로고
    • Biodegradable microparticles as a delivery system for the allergens of Dermatophagoides pteronyssinus (house dust mite). I. Preparation and characterisation of microparticles
    • Sharif S, Wheeler AW, O'Hagan DT. Biodegradable microparticles as a delivery system for the allergens of Dermatophagoides pteronyssinus (house dust mite). I. Preparation and characterisation of microparticles. Int J Pharm 1995; 119:239-46.
    • (1995) Int J Pharm , vol.119 , pp. 239-246
    • Sharif, S.1    Wheeler, A.W.2    O'Hagan, D.T.3
  • 64
    • 85004907668 scopus 로고
    • Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite
    • Scadding GK, Brostoft J. Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite. Clin Allergy 1986;16:483-91.
    • (1986) Clin Allergy , vol.16 , pp. 483-491
    • Scadding, G.K.1    Brostoft, J.2
  • 65
    • 85004774593 scopus 로고
    • Efficacy of grass-maize pollen oral immunotherapy in patients with seasonal hay fever
    • van Nierkirk CH, De Wet JI. Efficacy of grass-maize pollen oral immunotherapy in patients with seasonal hay fever. A double-blind study. Clin Allergy 1987;17: 507-13.
    • (1987) A Double-blind Study. Clin Allergy , vol.17 , pp. 507-513
    • Van Nierkirk, C.H.1    De Wet, J.I.2
  • 66
    • 0028232715 scopus 로고
    • A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract
    • Sabbah A, Hassoun S, Le Sellin J, André C, Sicard H. A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract. Allergy 1994;49:309-13.
    • (1994) Allergy , vol.49 , pp. 309-313
    • Sabbah, A.1    Hassoun, S.2    Le Sellin, J.3    André, C.4    Sicard, H.5
  • 67
    • 34250324823 scopus 로고    scopus 로고
    • Sublingual delivery of vaccines: Can we enhance the immune response induced by this route?
    • Wheeler AW, Sharif S. Sublingual delivery of vaccines: can we enhance the immune response induced by this route? Eur J Pharm Sci 1996;4 Suppl:539.
    • (1996) Eur J Pharm Sci , vol.4 , Issue.SUPPL. , pp. 539
    • Wheeler, A.W.1    Sharif, S.2
  • 69
    • 85036483296 scopus 로고    scopus 로고
    • Humoral immune responses to recombinant tree pollen allergens (Bet v 1, Bet v 2) in mice; construction of an oral allergy live vaccine
    • Vrtala S, Grote M, Ferreira F, et al. Humoral immune responses to recombinant tree pollen allergens (Bet v 1, Bet v 2) in mice; construction of an oral allergy live vaccine. Int Arch Allergy Appl Immunol.
    • Int Arch Allergy Appl Immunol.
    • Vrtala, S.1    Grote, M.2    Ferreira, F.3
  • 70
    • 0009566211 scopus 로고
    • Early clinical experience with T-cell reactive peptides from cat allergen Fei d 1
    • Norman PS, Ohman JL, Long AA. Early clinical experience with T-cell reactive peptides from cat allergen Fei d 1 [Abstract]. J Allergy Clin Immunol 1993;93:231.
    • (1993) J Allergy Clin Immunol , vol.93 , pp. 231
    • Norman, P.S.1    Ohman, J.L.2    Long, A.A.3
  • 71
    • 0000723146 scopus 로고
    • Follow on study of the first clinical trial with T cell defined peptides from cat allergen Fel d 1
    • Norman PS, Ohman JL, Long AA. Follow on study of the first clinical trial with T cell defined peptides from cat allergen Fel d 1 [Abstract]. J Allergy Clin Immunol 1995; 95:259.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 259
    • Norman, P.S.1    Ohman, J.L.2    Long, A.A.3
  • 72
    • 0027768657 scopus 로고
    • House dust mite allergy from T cell epitopes to immunotherapy
    • O'Hehir RE, Hoyne GF, Thomas WR. House dust mite allergy from T cell epitopes to immunotherapy. Eur J Clin Invest 1993;23:763-72.
    • (1993) Eur J Clin Invest , vol.23 , pp. 763-772
    • O'Hehir, R.E.1    Hoyne, G.F.2    Thomas, W.R.3


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