메뉴 건너뛰기




Volumn 812, Issue , 1997, Pages 92-97

Do recent operational studies indicate that a single state model is no longer applicable to G protein-coupled receptors?

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 0030752539     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48149.x     Document Type: Review
Times cited : (2)

References (24)
  • 1
    • 0023791358 scopus 로고
    • Are receptors promiscuous? Intrinsic efficacy as a transduction phenomenon
    • KENAKIN, T. P. 1988. Are receptors promiscuous? Intrinsic efficacy as a transduction phenomenon. Life Sci. 43: 1095-1101.
    • (1988) Life Sci. , vol.43 , pp. 1095-1101
    • Kenakin, T.P.1
  • 2
    • 0024432963 scopus 로고
    • Do pharmacological methods for the quantification of agonists work when the ternary complex mechanism operates?
    • LEFF, P. & D. HARPER. 1989. Do pharmacological methods for the quantification of agonists work when the ternary complex mechanism operates? J. Theor. Biol. 140: 381-397.
    • (1989) J. Theor. Biol. , vol.140 , pp. 381-397
    • Leff, P.1    Harper, D.2
  • 3
    • 0024013229 scopus 로고
    • Continuous variation of agonist affinity constants
    • MACKAY, D. 1988. Continuous variation of agonist affinity constants. Trends Pharmacol. Sci. 9: 156-157.
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 156-157
    • Mackay, D.1
  • 4
    • 0028861330 scopus 로고
    • Inverse agonism: Pharmacological curiosity or potential therapeutic strategy?
    • MILLIGAN, G., R. A. BOND & M. LEE. 1995. Inverse agonism: Pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol. Sci. 16: 10-13.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 10-13
    • Milligan, G.1    Bond, R.A.2    Lee, M.3
  • 5
    • 0001169515 scopus 로고
    • Antagonists with negative intrinsic activity at d opioid receptors coupled to GTP-binding proteins
    • COSTA, T. & A. HERZ. 1989. Antagonists with negative intrinsic activity at d opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. USA 86: 7321-7325.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7321-7325
    • Costa, T.1    Herz, A.2
  • 6
    • 0025238655 scopus 로고
    • Spontaneous association between opioid receptors and GTP-binding regulatory proteins in native membranes: Specific regulation by antagonists and sodium ions
    • COSTA, T., J. LANG, C. GLESS & A. HERZ. 1990. Spontaneous association between opioid receptors and GTP-binding regulatory proteins in native membranes: Specific regulation by antagonists and sodium ions. Mol. Pharmacol. 37: 383-394.
    • (1990) Mol. Pharmacol. , vol.37 , pp. 383-394
    • Costa, T.1    Lang, J.2    Gless, C.3    Herz, A.4
  • 7
    • 0019137579 scopus 로고
    • A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor
    • DELEAN, A., J. M. STADEL & R. J. LEFKOWITZ. 1980. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor. J. Biol. Chem. 255: 7108-7117.
    • (1980) J. Biol. Chem. , vol.255 , pp. 7108-7117
    • Delean, A.1    Stadel, J.M.2    Lefkowitz, R.J.3
  • 8
    • 0028176054 scopus 로고
    • 2-adrenergic receptor activation of G proteins: Evidence for a precoupled receptor/G protein state
    • 2-adrenergic receptor activation of G proteins: Evidence for a precoupled receptor/G protein state. Mol. Pharmacol. 45: 524-531.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 524-531
    • Wang-Ni, T.1    Duzic, E.2    Lanier, S.M.3    Deth, R.C.4
  • 11
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • LEFKOWITZ, R. J., S. COTECCHIA, P. SAMAMA & T. COSTA. 1993. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14: 303-307.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 13
    • 0027959963 scopus 로고
    • High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype
    • TIBERL, M. & M. G. CARON. 1994. High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype. J. Biol. Chem. 269: 27925-27931.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27925-27931
    • Tiberl, M.1    Caron, M.G.2
  • 15
    • 0029045445 scopus 로고
    • Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells
    • LABRECQUE, J., A. FARGIN, M. BOUVIER, P. CHIDIAC & M. DENNIS. 1995. Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Mol. Pharmacol. 48: 150-159.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 150-159
    • Labrecque, J.1    Fargin, A.2    Bouvier, M.3    Chidiac, P.4    Dennis, M.5
  • 16
    • 0028169068 scopus 로고
    • Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes
    • GOTZE, K. & K. H. JAKOBS. 1994. Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes. Eur. J. Pharmacol. 268: 151-158.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 151-158
    • Gotze, K.1    Jakobs, K.H.2
  • 17
    • 0027440691 scopus 로고
    • Activation of calcium currents in cardiac myocyte by empty β-adrenergic receptors
    • MEWES, T., S. DUTZ, U. RAVENS & K. H. JAKOBS. 1993. Activation of calcium currents in cardiac myocyte by empty β-adrenergic receptors. Circulation 88: 2916-2922.
    • (1993) Circulation , vol.88 , pp. 2916-2922
    • Mewes, T.1    Dutz, S.2    Ravens, U.3    Jakobs, K.H.4
  • 18
    • 0027462281 scopus 로고
    • Agonist-independent effects of muscarinic antagonists on Ca2+ and K+ currents in frog and rat cardiac cells
    • Lond.
    • HANF, R., Y. LI, G. SZABO & R. FISCHMEISTER. 1993. Agonist-independent effects of muscarinic antagonists on Ca2+ and K+ currents in frog and rat cardiac cells. J. Physiol. (Lond.) 461: 743-765.
    • (1993) J. Physiol. , vol.461 , pp. 743-765
    • Hanf, R.1    Li, Y.2    Szabo, G.3    Fischmeister, R.4
  • 20
    • 8544267549 scopus 로고
    • Personal communication
    • GURDAL, H. & M. JOHNSON. 1995. Personal communication.
    • (1995)
    • Gurdal, H.1    Johnson, M.2
  • 23
    • 0024578265 scopus 로고
    • Challenges for receptor theory as a tool for drug and drug receptor interactions
    • KENAKIN, T. P. 1989. Challenges for receptor theory as a tool for drug and drug receptor interactions. Trends Pharmacol. Sci. 10: 18-22.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 18-22
    • Kenakin, T.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.