Candidate gene study of eight GABA(A) receptor subunits in panic disorder

American Journal of Psychiatry

Volumn 154, Issue 8, 1997, Pages 1096-1100

  Crowe, Raymond R ^a   Wang, Zhewu ^a   Noyes Jr , Russell ^a   Albrecht, Barbara E ^a   Darlison, Mark G ^a   Bailey, Mark E S ^a   Johnson, Keith J ^a   Zoëga, Tómas ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; RECEPTOR SUBUNIT;

ADULT; ARTICLE; FEMALE; GENE MUTATION; GENETIC LINKAGE; HUMAN; HUMAN CELL; HUMAN TISSUE; ICELAND; MAJOR CLINICAL STUDY; MALE; PANIC; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR GENE; UNITED STATES;

EID: 0030752324     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.154.8.1096     Document Type: Article

References (37)

1. Zorumski CF, Eisenberg KE: Insights into the structure and function of GABA-benzodiazepine receptors: ion channels and psychiatry. Am J Psychiatry 1991; 148:162-173
2. Insel TR, Ninan PT, Aloi J, Jimerson DC, Skolnick P, Paul SM: A benzodiazepine receptor-mediated model of anxiety. Arch Gen Psychiatry 1984; 41:741-750
3. Dorow R, Horowski R, Paschelke G, Amin M: Severe anxiety induced by FG 7142, a β-carboline ligand for benzodiazepine receptors (letter). Lancet 1983; 2:98-99
4. A receptor subtypes: which, where and why? Seminars in the Neurosciences 1995; 7:115-126
5. A receptor-chloride ion channel complex. Neuropsychopharmacology 1991; 4:9-15
6. A receptor subunit mRNAs in the rat brain, I: telencephalon, diencephalon, mesencephalon. J Neurosci 1992; 12: 1040-1062
7. Pritchett DB, Seeburg PH: γ-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site. Proc Natl Acad Sci USA 1991; 88:1421-1425
8. A receptor expressed in Xenopus oocytes requires 8 amino acids contained in the γ2L subunit. Neuron 1991; 7:27-33
9. A receptor. Nature 1993; 361:356-359
10. Ptacek L: Ion channel shake-down. Nat Genet 1994; 8:111-112
11. Roy-Byrne PP, Cowley DS, Greenblatt DJ, Shader RI, Hommer D: Reduced benzodiazepine sensitivity in panic disorder. Arch Gen Psychiatry 1990; 47:534-538
12. Nutt DJ, Glue P, Lawson C, Wilson S: Flumazenil provocation of panic attacks: evidence for altered benzodiazepine receptor sensitivity in panic disorder. Arch Gen Psychiatry 1990; 47:917-925
13. Stewart SH, Pihl RO, Padjen AL: Chronic use of alcohol and/or benzodiazepines may account for evidence of altered benzodiazepine receptor sensitivity. Arch Gen Psychiatry 1992; 49:329-330
14. Spitzer RL, Williams JBW, Gibbon M, First MB: The Structured Clinical Interview for DSM-III-R (SCID), I: history, rationale, and description. Arch Gen Psychiatry 1992; 49:624-629
15. Endicott J, Spitzer RL: A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 1978; 35:837-844
16. Schmidt SM, Zoega T, Crowe RR: Excluding linkage between panic disorder and the γ-aminobutyric acid β1 receptor locus in five Icelandic pedigrees. Acta Psychiatr Scand 1993; 88:225-228
17. Di Nardo PA, Moras K, Barlow DH, Rapee RM, Brown TA: Reliability of the DSM-III-R anxiety disorder categories: using the Anxiety Disorders Interview Schedule - Revised (ADIS-R). Arch Gen Psychiatry 1993; 50:251-256
18. Adams P: LABMAN and LINKMAN: A data management system specifically designed for genome searches of complex diseases. Genet Epidemiol 1994; 11:87-98
19. Lathrop GM, Lalouel JM, Julier C, Ott J: Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci USA 1984; 81:3443-3446
20. Risch N: A new statistical test for linkage heterogeneity. Am J Hum Genet 1988; 42:353-364
21. Weeks DE, Lange K: The affected-pedigree-member method of linkage analysis. Am J Hum Genet 1988; 42:315-326
22. A receptor gene to human chromosome 4, using a tetranucleotide repeat polymorphism. Am J Hum Genet 1991; 49:621-626
23. A receptor α3-subunit gene. Nucleic Acids Res 1991; 19:4016
24. A receptor α1-subunit gene (GABRA1) to distal 5q by linkage analysis. Genomics 1992; 14:745-748
25. Glatt KA, Sinnen D, Lalande M: Dinucleotide repeat polymorphism at the GABAA receptor α5 (GABRA5) locus at chromosome 15q11-q13. Hum Mol Genet 1992; 1:348
26. A receptor β3 (GABRB3) locus in the Angelman/Prader-Willi region (AS/PWS) of chromosome 15. Hum Mol Genet 1992; 1:67
27. A receptor gene clusters are derived from an ancestral cluster. Genomics 1995; 25:580-586
28. A receptor subunit genes: relationship to human genetic disease. Neuron 1989; 3:647-654
29. Wilcox AS, Warrington JA, Gardiner K, Berger R, Whiting P, Altherr MR, Wasmuth JJ, Patterson D, Sikela JM: Human chromosomal localization of genes encoding the γ1 and γ2 subunits of the γ-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome. Proc Natl Acad Sci USA 1992; 89:5857-5861
30. A receptor isoform. Genomics 1994; 23:528-533
31. Greger V, Knoll JHM, Woolf E, Glatt K, Tyndale RF, DeLorey TM, Olsen RW, Tobin AJ, Sikela JM, Nakatsu Y, Brilliant MH, Whiting PJ, Lalande M: The γ-aminobutyric acid receptor γ3 subunit gene (GABRG3) is tightly linked to the α5 subunit gene (GABRA5) on human chromosome 15q11-q13 and is transcribed in the same orientation. Genomics 1995; 26:258-264
32. 6-subunit gene (GABRA6) to distal chromosome 5q by linkage analysis. Genomics 1994; 20:285-288
33. Ott J: Human Genetic Linkage. Baltimore, Johns Hopkins University Press, 1991, pp 203-213
34. Ploughman LM, Boehnke M: Estimating the power of a proposed linkage study for a complex genetic trait. Am J Hum Genet 1988; 44:543-551
35. Pauls DL, Bucher D, Crowe RR, Noyes R Jr: A genetic study of panic disorder pedigrees. Am J Hum Genet 1980; 32:639-644
36. Vieland VJ, Hodge SE, Lish JD, Adams P, Weissman MM: Segregation analysis of panic disorder. Psychiatr Genet 1993; 3:63-71
37. Risch N: Genetic linkage: interpreting lod scores. Science 1992; 255:803-804