Effect of methimazole and fish oil treatment on gentamicin nephrotoxicity in rats

Journal de Pharmacie de Belgique

Volumn 52, Issue 4, 1997, Pages 149-156

  El Daly, Ezzat S ^a  

^a Suez Canal University   (Egypt)

Author keywords

Fish oil; Gentamicin; Methimazole; Nephrotoxicity; Rats

Indexed keywords

FISH OIL; GENTAMICIN; GLUCOSAMINIDASE; THIAMAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY INJURY; LIVER FUNCTION; MALE; NEPHROTOXICITY; NONHUMAN; RAT; UREA NITROGEN BLOOD LEVEL;

ANIMALS; FISH OILS; GENTAMICINS; HORMONE ANTAGONISTS; KIDNEY; KIDNEY DISEASES; MALE; METHIMAZOLE; RATS;

EID: 0030751958     PISSN: 00472166     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. ABDEL GAYOUM A.A., ALI B.H., GHAWARSHA K., BASHIR A.A. (1993): Plasma lipid profile in rats with gentamicin-induced nephrotoxicity. Hum. Exp. Toxicol. 12: 371-375.
2. ALI B.H. and BASHIR A.A. (1994): Effect of fish oil treatment on gentamicin nephrotoxicity in rats. Ann. Nutr. Metab. 38(6): 336-339.
3. AUKEMA H.M., YAMAGUCHI T., TAKAHASHI H., PHILBRICK D.J., HOLUB B.J. (1992): Effect of dietary fish oil on survival and renal fatty acid composition in murine polycystic kidney disease. Nutr. Res. 12: 1383-1392.
4. BACELLI U.O., BEACH D.C., THOMPSON B., WEISS M., POLLACK V.E. (1988): A diet containing n-3 and n-6 fatty acids favorably alters the renal phospholipids, eicosanoid synthesis and plasma lipids in nephrotic rats. Lipids, 23: 1059-1063.
5. BACH, P.H. and LOCK, E.A. (1989):Eds. Nephrotoxicity, In vitro to In vivo, Animals to man, Plenum press, New York.
6. BAN, M., HETTICH, D. and HUGUET, N. (1991): Nephrotoxicity mechanism of cis-platinum (II) diamine dichloride in mice. Toxicol. Lett. 71: 161-168.
7. BEAUCHAMP, D., LAURENT, G., MALDAGUE, P., ABID, S., KISHORE, B., and TULKENS, P. (1990): Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by co-administration of poly-L-aspartic acid. J. Pharmacol. Exp. Ther. 255: 858-866.
8. BEYER, H.S. (1992): Lack of effect of hypothyroidism on rat liver regeneration. Biochem. Int. 27: 497-500.
9. BRADLEY, S.E., STEPHAN, F., COELHO, J.B. and REVILLE, P. (1974): The thyroid and the kidney. Kidney Int. 6: 346-365.
10. BRIGELUS, R., MUCKEL, C., AKERBOOM, T. and SIES, H. (1983): Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. Biochem. Pharmacol. 32: 2529-2534.
11. BROWN, W.D., (1960): Reduction of protein disulfide bonds by sodium borohydride. Biochem. Biophys. Acta, 44: 365-367.
12. CLARK, W.F., PARBTANI, A., NAYLOR, D., LEVINTON, C.M., MUIRHEAD, N., SPANNER, E., HUGG, M.W, PHILBRICK, D.J., HOLUB, B.J. (1993): Fish oil in lupus nephritis: Clinical findings and methodological implications. Kidney Int. 44: 75-86.
13. COAN, C., JI, J., HIDEG, K. and MEHLHORN, R. (1992): Protein sulfhydryls are protected from irreversible oxidation by conversion to mixed disulfides. Arch. Biochem. Biophys. 295: 369-378.
14. CRONIN, R., INMAN, L., ECHE, T., SOUTHERN, P., and GRIGGS, M. (1989): Effect of thyroid hormone on gentamicin accumulation in rat proximal tubule lyosomes. Am. J. Physiol. 257: F86-F91.
15. DE BROE, M.E., GIULIANO, R.A., and VERPOOTEN, G.A. (1989): Aminoglycoside nephrotoxicity: mechanism and prevention. Adv. Exp. Med. Biol. 252: 233-245.
16. 35S-labeled thiocarbamides in rat hepatic microsomes. Biochem. Pharmacol. 43: 881-888.
17. DI MONTE, D., ROSS, D., BELLOMO, G., EKLOW, L. and ORRENIUS, S. (1984): Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch. Biochem. Biophys. 235: 334-342.
18. ELFARRA, A.A. (1992) Aliphatic Halo-genated Hydrocarbons. In Toxicology of the Kidney, ed. by J.B. Hook and R. Goldstein, Raven Press, New York, In press.
19. ELFARRA, A.A. (1993) Aliphatic Halo-genated Hydrocarbons. In Toxicology of the Kidney, 2 nd ed. by J.B. Hook and R. Goldstein, Raven Press, New York, pp. 387-413.
20. ELFARRA, A.A., DUESCHER, R.J., SAUSEN, P.J., O'HARA, T.M. and COOLEY, A.J. (1994): Methimazole protection of rats against gentamicin-induced nephrotoxicity. Can. J. Physiol. Pharmacol. 72: 1238-1244.
21. ELINGA, I., KELLY, VE., HOUGHTON, D.O., BENNETT, W.M. (1987): Modification of experimental nephrotoxicity with fish oil as the vehicle of cyclosporine. Transplant, 43: 27.
22. HOMAN VAN DER HEIDE, J.J., BILO, H.J. TEGZEES, A.M., DONKER, A.J., (1990): The effect of dietary supplementation with fish oil on renal function in cyclosporine-treated renal transplant recipients. Transplant, 49: 523-527.
23. KACEW, S., BERGERON, M.G. (1990): Pathogenic factors in aminoglycoside-induced nephrotoxicity. Toxicol. Lett. 51: 241-259.
24. KALOYANIDES, C.J. (1991): Metabolic interactions between drugs and renal tubulo-interstitial cells: role in nephrotoxicity. Kidney Int. 39: 531-540.
25. KAYS, S.E., CROWELL, W.A. and JOHNSON, M.A. (1991): Iron supplementation increases gentamicin nephrotoxicity in rats. J. Nutr. 121: 1869-1875.
26. LEUNG, F.W. (1992): Fish oil protects against ethanol-induced gastric mucosal injury in rats. Dig. Dis. Sci. 37: 636-637.
27. LOWRY, O.H., ROSEBROUGH, N.J., FARR, A.L. and RANDALL, R.J. (1951): Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
28. MARCHANT, B., LEES, J. and ALEXANDER, W. (1978): Antithyroid drugs. Pharmacol. Ther. Part B, 3: 305-348.
29. MARTINEZ-LOPEZ, J., GREENBERG, S.E. and KLING R.R. (1962): Drug-induced hepatic injury during methimazole therapy. Gastroenterology, 43: 84-87.
30. 2+. J. Biol. Chem. 260: 13035-13040.
31. NAKAJIMA, T., HISHIDA, A. and KATO, A. (1994): Mechanisms for protective effects of free radical scavengers on gentamicin-mediated nephropathy in rats. Am. J. Physiol. 266: F425-F431.
32. NOTO, A., OGAWA, Y., MORI, S., YOSHIOKA, M. KITAKAZE, T., HORI, T., NAKAMURA, M. and MIYAKE, T. (1983): Simple, rapid spectrophotometry of urinary N-acetyl-B-D-glucosaminidase, with use of a new chromogenic substrate. Clin. Chem. 29: 1713-1716.
33. PETRY, T.W. and Eling, T.E. (1987): The mechanism for the inhibition of prostaglandin H synthetase-catalyzed xenobiotic oxidation by methimazole. J. Biol. Chem. 262: 14112-12118.
34. PITTMAN, J.A., BESCHI, R.J. and Smitherman, T.C. (1971): Methimazole. Its absorption and excretion in man and tissue distribution in rats. J. Clin. Endocrinol. 33: 182-185.
35. RAMSAMMY, L., JOSEPOVITZ, C., LANE, B., and KALOYANIDES, G.J. (1990): Polyaspartic acid inhibits gentamicin-induced perturbations of phospholipid metabolism. Am. J. Physiol. 258: C1141-C1149.
36. RAMSAMMY, L.S., JOSEPOVITZ, C., LING, K., LANE B.P. and KALOYANIDES, G.J. (1986) Effects of diphenyl-phenylenediamine on gentamicin-induced lipid peroxidation and toxicity in rat renal cortex. J. Pharmacol. Exp. Ther. 238: 83-88.
37. REED, D.J. (1990): Glutathione, toxicological implications. Annu. Rev. Pharmacol. Toxicol. 30: 603-631.
38. 2synthesis in rats ? Prostaglandins Leukot. Essent. Fatty Acids. 45: 131-136.
39. SAUSEN, P.J. and ELFARRA, A.A. (1990): Cysteine conjugate S-oxidase: characterization of a novel enzymatic activity in rat hepatic and renal microsomes. J. Biol. Chem. 265: 6139-6145.
40. SAUSEN, P.J., ELFARRA, A.A. and COOLEY, A.J. (1992): Methimazole protection of rats against chemically induced kidney damage in vivo. J. Pharmacol. Exp. Ther. 260: 393-401.
41. 14C] methimazole in rat. Xenobiotica, 3: 121-132.
42. SPECK, R.F., LAUTERBURGH, B.H., (1991): Fish oil protects mice against acetaminophen hepatotoxicity in vivo. Hepatology 13: 557-561.
43. TIRMENSTEIN, M.A. and NELSON, S.D. (1990): Acettaminophen-induced oxidation of protein thiols. Contribution of impaired thiolmetabolizing enzymes and the breakdown of adenine nucleotides. J. Biol. Chem. 265: 3059-3065.
44. TUNE, B.M., FRAVERT, D. and HSU, C.-Y. (1989): Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin. Biochem. Pharmacol. 38: 795-802.
45. VAIL, D.M., ELFARRA, A.A., COOLEY, A.J., PANCIERA, D.L., MACEWEN, G.E. and SOERGEL, S.A. (1993): Methimazole as a protectant against cisplatin induced nephrotoxicity using the dog as a model. Cancer Chemother. Pharmacol. 33: 25-30.
46. WALKER, P.D. and SHAH, S.V. (1987): Gentamicin enhanced production of hydrogen peroxide by renal cortical mitochondria. Am. J. Physiol. 253: C495-C499.
47. WEISE, W.J., NATORI, Y., LEVINE, J.S., O'MEARA, M., MINTO, A.W., MANNING, E.C., GOLDSTEIN, D.J., ABRAHANSOM, D.R., SALANT, D.J. (1993): Fish oil has protective and therapeutic effects on proteinuria in passive Heymann nephritis. Kidney Int. 43: 359-368.
48. WU, D., GRIFFITH, O.W. and REIDENBERG, M.M. (1990): Lack of effect of glutathione depletion by L-butionine-S,R-sulfoximine on gentamicin nephrotoxicity in rats. Pharmacology, 40: 250-257.