Analysis of the first intron of tnfb gene by ncol RFLP in Koreans

Japanese Journal of Human Genetics

Volumn 42, Issue 2, 1997, Pages 357-362

  Park, Kyung Sook ^a  

^a Sungshin Women's University   (South Korea)

Author keywords

First intron; Koreans; NcoI RFLP; TNFB

Indexed keywords

DNA; LYMPHOTOXIN;

AMINO ACID SUBSTITUTION; ARTICLE; CHROMOSOME 6P; CONTROLLED STUDY; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; HUMAN CELL; INTRON; KOREA; PHENOTYPE; RACE DIFFERENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; ETHNIC GROUPS; GENE FREQUENCY; HUMANS; INTRONS; KOREA; LYMPHOTOXIN-ALPHA; LYMPHOTOXIN-BETA; MEMBRANE PROTEINS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030751326     PISSN: 09168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02766959     Document Type: Article

References (21)

1. Abraham LJ, Chin Du D, Zahedi K, Dawkins RL, Whitehead AS (1991): Haplotypic polymorphisms of the TNFB gene. Immunogenetics 33: 50-53
2. Badenhoop K, Schwarz G, Schleusener H, Weetman AP, Recks S, Peters H, Bottazzo GF, Usadel KH (1992): Tumor necrosis factor β gene polymorphisms in Graves' disease. J. Clin Endocrinol Metab 74: 287-291
3. Bettinotti MP, Hartung K, Deicher H, Messer G, Keller E, Weiss EH, Albert ED (1993): Polymorphism of the tumor necrosis factor beta gene in systemic lupus erythematosus: TNFB-MHC haplotypes. Immunogenetics 37: 449-454
4. Chung JH, Cho BY, Lee HK, Kim TG, Han H, Koh CS (1994): The tumor necrosis factor β*1 allele is linked significantly to HLA-DR8 in Koreans with atrophie autoimmune thyroiditis who are positive for throtropin receptor blocking antibody. J Korean Med Sei 9: 155-161
5. Fugger L, Morling N, Ryder LP, Georgsen J, Jakobsen BK, Svejgaard A, Andersen V, Oxholm P, Pedersen FK, Friis J, Halberg P (1989): Nco\ restriction fragment length polymorphism (RFLP) of the tumor necrosis factor (TNF-α) region in four autoimmune diseases. Tissue Antigens 34: 17-22
6. Goldstein R, Sengar DPS (1993): Comparative studies of the major histocompatibility complex in French Canadian and non-French Canadian Caucasians with systemic lupus erythematosis. Arthritis Rheum 36: 1121-1127
7. Hagihara M, Shimura T, Sato K, Genga K, Suzuki M, Tsuji K (1995): HLA and tumor necrosis factor gene polymorphisms in Okinawa lung cancer patients: comparative study with mainland Japan lung cancer patients. Hum Immunol 43: 95-100
8. Laitinen T, Lokki ML, Tulppala M, Ylikorkala O, Koskimies S (1992): Tumour necrosis factor B gene polymorphism in relation to complotype in couples with spontaneous abortions and in control families. Scand J Immunol 35: 131-135
9. Messer G, Spengler U, Jung MC, Honold G, Blomer K, Pape GR, Riethmuller G, Weiss EH (1991): Polymorphic structure of the tumor necrosis factor (TNF) locus: An Ncol polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J Exp Med 173: 209-219
10. Mizuki N, Inoko H, Sugimura K, Nishimura K, Nakamura S, Tanaka H, Mizuki N, Mizuki H, Inaba G, Tsuji K, Ohno S (1992): RFLP analysis in the TNF-β gene and the susceptibility to alloreactive NK cells in Behcet's disease. Invest Ophthalmol Visual Sei 33: 3084-3090
11. Nedospasov SA, Shakhov AN, Turetskaya RL, Mett VA, Azizov MM, Georgiev GP, Korobko VG, Dobrynin VN, Filippov SA, Bystrov NS, Boldyreva EF, Chuvpilo SA, Chumakov AM, Shingarova LN, Ovchinnikov YA (1986): Tandem arrangement of genes coding for tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β) in the human genome. Cold Spring Harbor Symp Quant Biol 51: 611-624
12. Nedwin GE, Naylor SL, Sakaguchi AY, Smith D, Jarret-Nedwin J, Pennica D, Goeddel DV, Gray PW (1985): Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal location. Nucleic Acids Res 13: 6361-6373
13. Partanen J, Koskimies S (1988): Low degree of DNA polymorphism in the HLA-linked lymphotoxin (tumor necrosis factor ) gene. Scand J Immunol 28: 313-316
14. Pociot F, Briant L, Jongeneel CV, Molvig J, Worsaae H, Abbal M, Thomsen M, Nerup J, Cambon-Thomsen A (1993): Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 23: 224-231
15. Shimura T, Hagihara M, Takebe K, Munkhbat B, Odaka T, Kata H, Nagamachi Y, Tsuji K (1994): The study of tumor necrosis factor beta gene polymorphism in lung cancer patients. Cancer 73: 1184-1188
16. Shimura T, Hagihara M, Takebe K, Munkhbat B, Ogoshi K, Mitomi T, Nagamachi Y, Tsuji K (1995): 10.5kb homozygote of tumor necrosis factor-beta gene is associated with a better prognosis in gastric cancer patients. Cancer 75: 1450-1453
17. Spies T, Morton CC, Nedospasov SA, Fiers W, Poius D, Strominger JL (1986): Genes for the tumor necrosis factors a and are linked to the human major histocompatibility complex. Proc Natl Acad Sei USA 83: 8699-8702
18. Sung SSJ, Bjorndahl JM, Wang CY, Kao HT, Fu SM (1988a): Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J Exp Med 167: 937-953
19. Sung SSJ, Jung LKL, Walters JA, Chen W, Wang CY, Fu SM (1988b): Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells. J Exp Med 168: 1539-1551
20. Webb GC, Chaplin DD (1990): Genetic variability at the human tumor necrosis factor loci. J Immunol 145: 1278-1285
21. Yamagata K, Hanafusa T, Nakajima H, Sada M, Amemiya H, Noguchi T, Tanaka T, Kono N, Tarui S (1991): HLA-DQA1*1 contributes to resistance and A1*1 confers susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 34: 133-136