Mode of inhibition of HIV reverse transcriptase by 2-hexaprenyl-hydroquinone, a novel general inhibitor of RNA-and DNA-directed DNA polymerases

Biochemical Journal

Volumn 324, Issue 3, 1997, Pages 721-727

  Loya, Shoshana ^a   Rudi, Amira ^a   Kashman, Yoel ^a   Hizi, Amnon ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DIRECTED DNA POLYMERASE; ENZYME INHIBITOR; HYDROQUINONE DERIVATIVE; HYDROXYL GROUP; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS ENZYME;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; METHYLATION; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV-1 REVERSE TRANSCRIPTASE; LEUKEMIA VIRUS, MURINE; PORIFERA; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; TEMPLATES, GENETIC; TERPENES;

ESCHERICHIA COLI; HIV 1; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; IRCINIA; LEUKAEMIA VIRUS; MURINAE;

EID: 0030751097     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3240721     Document Type: Article

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