Evidence for recombination in the flagellin locus of Campylobacter jejuni: Implications for the flagellin gene typing scheme

Journal of Clinical Microbiology

Volumn 35, Issue 9, 1997, Pages 2386-2392

  Harrington, Clare S ^a,c   Thomson Carter, Fiona M ^b   Carter, Philip E ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b Scottish Campylobacter Ref Lab   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

ARTICLE; BACTERIAL GENE; CAMPYLOBACTER JEJUNI; FLAGELLATE; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC RECOMBINATION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BACTERIA (MICROORGANISMS); CAMPYLOBACTER JEJUNI; MASTIGOPHORA (FLAGELLATES);

EID: 0030750202     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.35.9.2386-2392.1997     Document Type: Article

References (26)

1. Alm, R. A., P. Guerry, and T. J. Trust. 1993. Significance of duplicated flagellin genes in Campylobacter. J. Mol. Biol. 230:359-363.
2. Birkenhead, D., P. M. Hawkey, J. Heritage, D. M. Gascoyne-Binzi, and P. Kite. 1993. PCR for the detection and typing of campylobacters. Lett. Appl. Microbiol. 17:235-237.
3. Dowson, C. G., T. J. Coffey, and B. G. Spratt. 1994. Origin and molecular epidemiology of penicillin-binding-protein-mediated resistance to β-lactam antibiotics. Trends Microbiol. 2:361-366.
4. Fischer, S. H., and I. Nachamkin. 1991. Common and variable domains of the flagellin gene, flaA, in Campylobacter jejuni. Mol. Microbiol. 5:1151-1158.
5. Forbes, K. J., Z. Fang, and T. H. Pennington. 1995. Allelic variation in the Helicobacier pylori flagellin genes flaA and flaB: its consequences for strain typing schemes and population structure. Epidemiol. Infect. 114:257-266.
6. Guerry, P., R. A. Alm, M. E. Power, S. M. Logan, and T. J. Trust. 1991. Role of two flagellin genes in Campylobacter motility. J. Bacteriol. 173:4757-4764.
7. Guerry, P., S. M. Logan, S. Thornton, and T. J. Trust. 1990. Genomic organization and expression of Campylobacter flagellin genes. J. Bacteriol. 172:1853-1860.
8. Khawaja, R., K. Neote, H. L. Bingham, J. L. Penner, and V. L. Chan. 1992. Cloning and sequence analysis of the flagellin gene of Campylobacter jejuni TGH9011. Curr. Microbiol. 24:213-221.
9. Li, J., K. Nelson, A. C. McWhorter, T. S. Whittam, and R. K. Selander. 1994. Recombinational basis of serovar diversity in Salmonella enterica. Proc. Natl. Acad. Sci. USA 91:2552-2556.
10. Maynard Smith, J. 1992. Analyzing the mosaic structure of genes. J. Mol. Evol. 34:126-129.
11. Nachamkin, I., K. Bohachick, and C. M. Patton. 1993. Flagellin gene typing of Campylobacter jejuni by restriction fragment length polymorphism analysis. J. Clin. Microbiol. 31:1531-1536.
12. Nachamkin, I., H. Ung, and C. M. Patton. 1996. Analysis of HL and O serotypes of Campylobacter strains by the flagellin gene typing system. J. Clin. Microbiol. 34:277-281.
13. Nuijten, P. J. M., F. J. A. M. van Asten, W. Gaastra, and B. A. M. van der Zeijst. 1990. Structural and functional analysis of two Campylobacter jejuni flagellin genes. J. Biol. Chem. 265:17798-17804.
14. Owen, R. J., C. Fitzgerald, K. Sutherland, and P. Borman. 1994. Flagellin gene polymorphism analysis of Campylobacter jejuni infecting man and other hosts and comparison with biotyping and somatic antigenic serotyping. Epidemiol. Infect. 113:221-234.
15. Penner, J. L., and J. N. Hennessey. 1980. Passive hemagglutination technique for serotyping Campylobacter fetus subsp. jejuni on the basis of soluble heat stable antigens. J. Clin. Microbiol. 12:732-737.
16. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
17. Santesteban, E., J. Gibson, and R. J. Owen. 1996. Flagellin gene profiling of Campylobacter jejuni heat-stable serotype 1 and 4 complex. Res. Microbiol. 147:641-649.
18. Sawyer, S. 1989. Statistical tests for detecting gene conversion. Mol. Biol. Evol. 6:526-538.
19. Skirrow, M. B., and M. J. Blaser. 1992. Clinical and epidemiologic considerations, p. 3-9. In I. Nachamkin, M. J. Blaser, and L. S. Tompkins (ed.), Campylobacter jejuni: current status and future trends. American Society for Microbiology, Washington, D.C.
20. Smith, N. H., P. Beltran, and R. K. Selander. 1990. Recombination of Salmonella phase 1 Hagellin genes generates new serovars. J. Bacteriol. 172:2209-2216.
21. Wang, Y., and D. E. Taylor. 1990. Natural transformation in Campylobacter species. J. Bacteriol. 172:949-955.
22. Wareing, D. R. A. Personal communication.
23. + mutant of Campylobacter jejuni. Infect. Immun. 62:3901-3906.
24. Wassenaar, T. M., N. M. C. Bleumink-Pluym, and B. A. M. van der Zeijst. 1991. Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion. EMBO J. 10:2055-2061.
25. Wassenaar, T. M., B. N. Fry, and B. A. M. van der Zeijst. 1995. Variation of the flagellin gene locus of Campylobacter jejuni by recombination and horizontal gene transfer. Microbiology 141:95-101.
26. Wilson, D. R., and T. J. Beveridge. 1993. Bacterial flagellar filaments and their component flagellins. Can. J. Microbiol. 39:451-472.