The molecular basis of the Kidd blood group polymorphism and its lack of association with type 1 diabetes susceptibility

Human Molecular Genetics

Volumn 6, Issue 7, 1997, Pages 1017-1020

  Olivès, Bernadette ^a   Merriman, Marilyn ^b   Bailly, Pascal ^a   Bain, Stephen ^c   Barnett, Anthony ^c   Todd, John ^b   Cartron, Jean Pierre ^a   Merriman, Tony ^b  

^a INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MESSENGER RNA; UREA;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD GROUP KIDD SYSTEM; CHROMOSOME 18Q; CONGENITAL DISORDER; DNA POLYMORPHISM; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; IMMUNOGENETICS; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETICULOCYTE; REVERSE TRANSCRIPTION;

ADOLESCENT; ADULT; ALLELES; CLONING, MOLECULAR; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KIDD BLOOD-GROUP SYSTEM; LINKAGE (GENETICS); POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEQUENCE ANALYSIS, DNA;

EID: 0030750176     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.7.1017     Document Type: Article

References (24)

1. Daniels, G. (1995) In Human Blood Groups. Blackwell Scientific Ltd, London, pp. 440-451.
2. Heaton, D.C. and McLoughlin, K. (1982) Jk(a-b-) red blood cells resist urea lysis. Transfusion, 22, 70-71.
3. Fröhlich, O., Macey, R.I., Edwards-Moulds, J., Gargus, J.J. and Gunn, R.B. (1991) Urea transport deficiency in Jk(a-b-) erythrocytes. Am. J. Physiol., 260, C778-C783.
4. Olivès, B., Neau, P., Bailly, P., Hediger, M.A., Rousselet, G., Cartron, J.P. and Ripoche, P. (1994) Cloning and functional expression of a urea transporter from human bone marrow cells. J. Biol. Chem., 269, 31649-31652.
5. Olivès, B., Mattei, M.G., Huet, M., Neau, P., Martial, S., Cartron, J.P. and Bailly, P. (1995) Kidd blood group and urea transport of human erythrocytes are carried by the same protein. J. Biol. Chem., 270, 15607-15610.
6. Geitvik, G.A., Hoyheim, B., Gedde-Dahl, T., Grzeschilk, K.H., Lothe, R., Tomter, H. and Olaisen, B. (1987) The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLP. Hum. Genet., 77, 205-209.
7. Xu, Y., Olivès, B., Bailly, P., Ripoche, P., Ronco, P., Cartron. J.P. and Rondeau, E. (1997) Endothelial cells of the kidney vasa recta express the urea transporter HUTI1. Kidney Int., in press.
8. Cucca, F. and J.A. Todd. (1996) In Browning, M.J. and McMichael, A.J. (eds), HLA/MHC: Genes, Molecules and Function. BIOS Scientific Publishers, Oxford, pp 383-406.
9. Bennett, S.T., Lucassen, A.M., Gough, S.C.L., Powell, E.E., Undlien, D.E., Pritchard, L.E., Merriman, M.E., Kawaguchi, Y., Dronsfield, M., Pociot, F., Nerup, J., Bouzekri, N., Cambon-Thomsen, A.. Rønningen, K.S., Barnett, A.H., Bain, S.C. and Todd, J.A. (1995) Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genet., 9, 284-292.
10. Davies, J.L., Cucca, F., Goy, J.V., Atta, Z.A.A., Merriman, M.E., Wilson, A., Barnett, A.H., Bain, S.C. and Todd, J.A. (1996) Saturation multipoint linkage mapping of chromosome 6q in type 1 diabetes. Hum. Mol. Genet., 5, 1071-1074.
11. Luo, D.F., Buzzetti, R., Rotter, J.I., Maclaren, N.K., Raffel, L.J., Nisticò, L., Giovannini, C., Pozzilli, P., Thomson, G. and She, J.-X. (1996) Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8. Hum. Mol. Genet., 5, 693-698.
12. Merriman, T., Twells, R., Merriman, M., Eaves. I., Cox, R., Cucca, F., McKinney, P., Shield, J., Baum, D., Bosi, E., Pozzilli, P., Nisticò, L., Buzzetti, R., Joner, G., Rønningen, K., Thorsby, E., Undlien, D., Pociot, F., Nerup, J., Bain, S., Barnett, A. and Todd, J. (1997) Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21. Hum. Mol. Genet., 6, 1003-1010.
13. Nisticò, L., Buzzetti, R., Pritchard, L.E., Van der Auwera, B., Giovannini, C., Bosi, E., Larrad, M.T.M., Rios, M.S., Chow, C.C., Cockram, C.S., Jacobs, K., Mijovic, C., Bain, S.C., Barnett, A.H., Vandewalle, C.L., Schuit, F., Gorus, F.K., Belgian Diabetes Registry, Tosi, R., Pozzilli, P. and Todd, J.A. (1996) The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum. Mol. Genet., 5, 1075-1080.
14. Hodge, S.E., Anderson, C.E., Neiswanger, K., Field, L.L., Spence, M.A., Sparkes, R.S., Sparkes, M., Christ, M., Terasaki, P.I., Rimoin, D.L. and Rotter, J.I. (1982) Close genetic linkage between diabetes mellitus and Kidd blood group. Lancet, 2, 893.
15. b allele. J. Clin. Endocrinol Metab., 55, 193-195.
16. Hodge, S.E., Anderson, C.E., Neiswanger, K., Sparkes, R.S. and Rimoin, D.L. (1983) The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity. Am. J. Hum. Genet., 35, 1139-1155.
17. Dunsworth, T.S., Rich, S.S., Swanson, J. and Barbosa, J. (1982) No evidence for linkage between diabetes and the Kidd marker. Diabetes, 31, 991-993.
18. Davies, J.L., Kawaguchi, Y., Bennett, S.T., Copeman, J.B., Cordell, H.J., Pritchard, L.E., Reed, P.W., Gough, S.C.L., Jenkins, S.C., Palmer, S.M., Balfour, K.M., Rowe, B., Farrall, M., Barnett, A.H., Bain, S.C. and Todd, J.A. (1994) A genome-wide search for human type 1 diabetes susceptibility genes. Nature, 371, 130-136.
19. Spielman, R., McGinnis, R. and Ewens, W. (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet., 52, 506-516.
20. Bain, S.C., Todd, J.A. and Barnett, A.H. (1990) The British Diabetic Association - Warren Repository. Autoimmunity, 7, 83-85.
21. Lemmark, A., Ducat, L., Eisenbarth, G., Ott, J., Permutt, M.A., Rubenstein, P. and Spielman, R. (1990) Family cell lines available for research. Am. J. Hum. Genet., 47, 1028-1030.
22. Lazano, E.M., Grau, O. and Romanowski, V. (1993) Isolation of RNA from whole blood for reliable use in RT-PCR amplification. Trends Genet., 9, 296.
23. Risch, N. (1990) Linkage strategies for genetically complex traits. I. Multilocus models. Am. J. Hum. Genet., 46, 222-228.
24. Nerup, J., Platz, P., Andersen, O., Christy, M., Lyngsoe, J., Poulsen, J., Ryder, L., Thomsen, M., Nielsen, L. and A. Svejgaard (1974) HLA antigens in diabetes mellitus. Lancet, 2, 864.