Rapid mid-trimester prenatal diagnosis of beta-thalassaemia and other haemoglobinopathies using a non-radioactive anion exchange HPLC technique - an Indian experience

Prenatal Diagnosis

Volumn 17, Issue 8, 1997, Pages 725-731

  Rao, V B ^a   Natrajan, P G ^a   Lulla, C P ^a   Bandodkar, S B ^a  

^a B J WADIA HOSPITAL FOR CHILDREN   (India)

Author keywords

thalassaemia; Anion exchange HPLC; Haemoglobinopathies; Prenatal diagnosis

Indexed keywords

CARBOXYMETHYLCELLULOSE; HEMOGLOBIN A;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BETA THALASSEMIA; BLOOD SAMPLING; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HEMOGLOBINOPATHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INDIA; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; RELIABILITY; SICKLE CELL ANEMIA; UMBILICAL CORD BLOOD;

ADULT; ANEMIA, SICKLE CELL; BETA-THALASSEMIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; FEMALE; FETAL BLOOD; HEMOGLOBIN A; HEMOGLOBINOPATHIES; HUMANS; INDIA; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PRENATAL DIAGNOSIS;

EID: 0030749959     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(199708)17:8<725::AID-PD134>3.0.CO;2-8     Document Type: Article

References (16)

1. Alter, B.P. (1988). Prenatal diagnosis: general introduction, methodology and review, Hemoglobin, 12, 763-772.
2. Alter, B.P., Stump, D.O. (1987). Prenatal diagnosis of haemoglobinopathies: a potential application of high performance liquid chromatography, Hemoglobin, 11, 341-352.
3. Alter, B.P., Coupal, E., Forget, B.F. (1981). Globin chain electrophoresis for prenatal diagnosis of β thalassaemia, Hemoglobin, 5, 357-370.
4. Congote, L.F. (1981). Rapid procedure for globin chain analysis in blood samples of normal and beta thalassaemia foetuses, Blood, 57, 353-360.
5. Dubart, A., Goossens, M., Beuzard, Y., Monplaisir, N., Testa, U., Basset, P., Rosa, J. (1980). Prenatal diagnosis of haemoglobinopathies: comparison of the results obtained by isoelectric focusing by haemoglobinopathies and by chromatography of globin chains, Blood, 5, 1091-1099.
6. Fessard, P.R., Plassa, F., Blouquit, Y., Vidaud, M., Varnavides, L., Mibashan, R.S., Bellingham, A., Beuzard, Y. (1989). Prenatal diagnosis of haemoglobinopathies by ion exchange HPLC of hemoglobins, Prenat. Diagn., 9, 19-26.
7. Gianni, A.M., Polli, El., Giglioni, B., Comi, P., Ottolenghi, S., Ferrari, M., Furbetta, M., Angius, A., Cao, A. (1981). Isoelectric focusing of globin chains for antenatal diagnosis of β thalassaemia. Hemoglobin, 5, 349-356.
8. Hanash, S.M., Shapiro, D.M. (1981). Separation of human haemoglobins by ion exchange HPLC, Hemoglobin, 5, 165-175.
9. Kleihauer, E., Braun, H., Betke, K. (1957). Demonstration von fetalem Hemoglobin in den Erythrocyten eines Blutausstrichs, Klin. Wochenschr., 35, 637-639.
10. Longinotti, M., Pistidda, P., Oggiano, L., Guiso, L., Frogheri, L., Dore, F., Pardini, S., Bonfigli, S., Rimini, E., Angioni, S. (1994). A 12 year preventive program for β thalassaemia in northern Sardinia, Clin. Genet., 46, 238-243.
11. Maiavacca, R., Tedeschi, S., Mosca, A., Calmi, S., Leonardis, P.D., Todaro, C., Zuliani, G., Buscaglia, M., Cantu-Raynaldi, A. (1992). Non-radioactive quantification of low concentrations of haemoglobin A by HPLC for midtrimester prenatal diagnosis of β thalassaemia, Clin. Chem., 38, 1906-1908.
12. Matsakis, M., Berdoukas, V.A., Angastiniotis, M., Mouzoras, M., Ioannou, P., Ferrari, M., Modell, B., Fairweather, D.V.I., Ward, R.H.T., Loukopoulos, D., Sakarellou, N. (1980). Hematological aspects of antenatal diagnosis for thalassaemia in Britain, Br. J. Haematol., 46, 185-197.
13. 6PD deficiency in tribes of Maharashtra. India, Gene-Geogr., 4, 131-134.
14. Shelton, J.B., Shelton, J.R., Schroeder, W.A., Powars, D.R. (1985). Hemoglobin Aztech or alpha 2 76 (EF5) Met-Thr beta 2 detection of a silent mutant by HPLC, Hemoglobin, 9, 325-332.
15. Trapani, F.D., Marino, M., D'Alcamo, E., Abate, I., D'Aostino, S., Lauricella, S., Musico, M., Ordlandi, F., Sammarco, P., Maggio, A. (1991). Prenatal diagnosis of haemoglobin disorders by cordocentesis at 12 weeks' gestation, Prenat. Diagn., 11, 899-904.
16. Weatherall, D.J., Clegg, J.B. (1981). The beta thalassaemias. In: The Thalassaemia Syndromes, 3rd edn, Oxford: Blackwell Scientific, 150-153.