Longitudinal studies on the interaction of perfluorochemicals with liver cytochromes P-450 by means of testing the rate of detoxification of pentobarbital

Advances in Experimental Medicine and Biology

Volumn 411, Issue , 1997, Pages 391-394

  Lutz, J ^a   Krafft, M P ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIS(PERFLUOROBUTYL)ETHYLENE; CYTOCHROME P450; PERFLUORO COMPOUND; PHENOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DETOXIFICATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SUBSTRATE COMPLEX; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RIGHTING REFLEX; SLEEP TIME;

ANIMALIA;

EID: 0030749709     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5865-1_50     Document Type: Article

References (10)

1. Cornélus C, Krafft MP, Riess JG: Mixed fluorocarbon/hydrocarbon molecular dowels help protect concentrated fluorocarbon emulsions with large size droplets against coalescence. Art. Cells, Blood Subs. Immob. Biotech. 22, 1267-1272 (1994)
2. Sharma SK, Bollands AD, Davis SS, Lowe KC: Emulsified perfluorochemicals as physiological oxygen-transport fluids: assessment of a novel formulation. Advanc. Exp. Med. Biol. 215, 97-108 (1987)
3. Meinert H, Fackler R, Knoblich A, Mader J, Reuter P, Röhlke W: On the perfluorocarbon emulsions of second generation. Biomat. Art. Cells Immob. Biotech. 20, 805-818 (1992)
4. Ullrich V, Diehl H: Uncoupling of monooxygenation and electron transport by fluorocarbons in liver microsomes. Europ. J. Biochem. 20, 509-512 (1971)
5. Lutz J, Wagner M: Recovery from pentobarbital-induced sleep after administration of perfluorinated blood substitutes. Artificial Organs 8, 41-43 (1984)
6. Obraztsov VV, Shekhtman DG, Sologub GR, Beloyartsev FF: Induction of microsomal cytochromes in the rat liver after intravenous injection of an emulsion of perfluoroorgannic compounds. Biokhimiya 50, 1220-1227 (1985)
7. Huang R, Cooper DY, Sloviter A: Effects of intravenous emulsified perfluorochemicals on hepatic cytochrome P-450. Biochem. Pharmacol. 36, 4331-4334 (1987)
8. Shrewsbury RP, Oliver SR, White LG: The effect of moderately severe hemodilution with Fluosol-DA on cytochrome P-450 mediated antipyrine metabolism. Biomat. Art. Cells Art. Organs 17, 393-402 (1989)
9. Lowe KC, Armstrong FH: Biocompatibility studies with perfluochemical oxygen carriers. Biomat. Art. Cells Immob. Biotech. 20, 993-999 (1992)
10. Obraztsov VV, Grishanova AY, Shekhtman DG, Sklifas AN, Makarov KN: Interaction of perfluorooctylbromide with liver microsomal monooxygenase. Biokhimiya 58, 1234-1239 (1993). Translation by Plenum Pub. Corp. (1993)