Fermentable dietary fibre, intestinal microflora and plasma hormones in the rat

Clinical Science

Volumn 93, Issue 2, 1997, Pages 109-112

  Ghatei, M A ^a   Ratcliffe, B ^b   Bloom, S R ^a   Goodlad, R A ^a,c  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b ROBERT GORDON UNIVERSITY   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Enteroglucagon; Fibre; Gastrin; Gastrointestinal hormones; Insulin; Microflora; Peptide YY

Indexed keywords

GASTRIN; GASTROINTESTINAL HORMONE; INSULIN; OXYNTOMODULIN; PEPTIDE YY;

ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIETARY FIBER; EPITHELIUM CELL; FERMENTATION; GASTRIN BLOOD LEVEL; HORMONE BLOOD LEVEL; INSULIN BLOOD LEVEL; INTESTINE FLORA; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH MUCOSA;

EID: 0030749441     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0930109     Document Type: Article

References (21)

1. Goodlad RA, Plumb JA, Wright NA. The relationship between intestinal crypt cell proliferation and water absorption measured in vitro in the rat. Clin Sci 1987; 72: 297-304.
2. Goodlad RA, Lee CY, Wright NA. Cell proliferation in the small intestine and colon of intravenously fed rats: effects of urogastrone-epidermal growth factor. Cell Prolif 1992; 25: 393-404.
3. Janne P, Carpenter Y, Willems G. Colonic mucosal atrophy induced by a liquid elemental diet in rats. Am J Dig Dis 1977; 22: 808-12.
4. Goodlad RA, Wright NA. The effects of addition of cellulose or kaolin to an elemental diet on intestinal cell proliferation in the mouse. Br J Nutr 1983; 50: 91-8.
5. Goodlad RA, Lenton W, Ghatei MA, Adrian TE, Bloom SR, Wright NA. Effects of an elemental diet, inert bulk and different types of dietary fibre on the response of the intestinal epithelium to refeeding in the rat and relationship to plasma gastrin, enteroglucagon, and PYY concentrations. Gut 1987; 28: 171-80.
6. Pell JD, Johnson IT, Goodlad RA. The effects of, and interactions between, fermentable dietary fibre and lipid in germ free and conventional mice. Gastroenterology 1995; 108: 1745-52.
7. Goodlad RA, Ratcliffe B, Lee CY, Wright NA. Dietary fibre and the gastrointestinal tract: differing trophic effects on muscle and mucosa of the stomach, small intestine and colon. Eur J Clin Nutr 1995; 49 (Suppl. 3): S178-81.
8. Heaton KW. Concepts of dietary fibre. In: Southgate DAT, Waldron K, Johnson IT, Fenwick GR, eds. Dietary fibre: chemical and biological aspects. Cambridge: The Royal Society of Chemistry, 1990: 3-10.
9. Cummings JH, Pomare EW, Branch WJ, Naylor C, Macfarlane GT. Short chain fatty acids in human large intestine, portal hepatic and venous blood. Gut 1987; 28: 1221-7.
10. Sakata T, Yajima T. Influence of short chain fatty acids on the epithelial cell division of digestive tracts. Q J Exp Physiol 1984; 69: 639-48.
11. Goodlad RA, Wright NA. Growth control factors in the gastrointestinal tract. Bailliere's Clin Gastroenterol 1990; 4: 97-119.
12. Goodlad RA, Ratcliffe B, Fordham JP, Wright NA. Does dietary fibre stimulate intestinal epithelial cell proliferation in germ free rats? Gut 1989; 30: 820-5.
13. Gustafsson BE. Lightweight stainless steel systems for rearing germ-free animals. Ann NY Acad Sci 1959; 78: 17-28.
14. Ekundayo B, Lee CY, Goodlad RA. The effects of gastrin on intestinal epithelial cell proliferation in parenterally fed rats. Gut 1995; 36: 203-9.
15. Hagander B. Fibre and the diabetic diet: an evaluation of the metabolic response to standardized meals. Acta Med Scand Suppl 1987; 716: 1-55.
16. Mazur A, Remesy C, Demigne C. The effect of high-fibre diet on plasma lipoproteins and hormones in genetically obese Zucker rats. Eur J Clin Invest 1990; 20: 600-6.
17. Gee JM, Lee Finglas W, Johnson IT. Fermentable carbohydrate modulates postprandial enteroglucagon and gastrin release in rats. Br J Nutr 1996; 75: 757-66.
18. Gustafsson BE. The physiological importance of the colonic microflora. Scand J Gastroenterol 1982; 77: 117-31.
19. Nogueira AMMF, Barbosa AJA. Immunocytochemical study of intestinal endocrine-cells in germ-free mice. Eur J Histochem 1994; 38: 213-18.
20. Uribe A, Midtvedt T, Jaramillo E, Theodorsson E. Epithelial cell proliferation in the proximal small intestine of germ free rats. Acta Chir Scand 1991; 562: 87-92.
21. Gee JM, Lee Finglas W, Wortley GW, Johnson IT. Fermentable carbohydrates elevate plasma enteroglucagon but high viscosity is also necessary to stimulate small bowel mucosa) cell proliferation in rats. J Nutr 1996; 126: 373-9.