Frequent and frequently overlooked: Treatment-induced endocrine dysfunction in adult long-term survivors of primary brain tumors

Neurology

Volumn 49, Issue 2, 1997, Pages 498-506

  Arlt, W ^a,b   Hove, U ^a   Muller B ^a   Reincke, M ^a   Berweiler, U ^a   Schwab, F ^a   Allolio, B ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBAMAZEPINE; CARMUSTINE; CLONAZEPAM; CORTICOTROPIN; CYTARABINE; ESTRADIOL; ETOPOSIDE; FOLLITROPIN; HYDROCORTISONE; LIOTHYRONINE; LUTEINIZING HORMONE; NIMUSTINE; PHENYTOIN; PRASTERONE; PRASTERONE SULFATE; PRIMIDONE; PROLACTIN; TENIPOSIDE; TESTOSTERONE; THYROTROPIN; VALPROIC ACID;

ADULT; AGED; ARTICLE; BRAIN TUMOR; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HORMONE DETERMINATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERPROLACTINEMIA; HYPOGONADISM; MALE; NEUROENDOCRINE DISEASE; PRIORITY JOURNAL; QUALITY OF LIFE; SURVIVAL TIME;

EID: 0030749006     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.49.2.498     Document Type: Article

References (33)

1. Lam KSL, Tse VKC, Wang C, Yeung RTT, Ho JHC. Effects of cranial irradiation on hypothalamic-pituitary function - a 5-year longitudinal study in patients with nasopharyngeal carcinoma. Q J Med 1990;286:165-176.
2. Brauner R, Rappaport R, Prevot, et al. A prospective study of the development of growth hormone deficiency in children given cranial irradiation, and its relation to statural growth. J Clin Endocrinol Metab 1989;68:346-351.
3. Littley MD, Shalet SM, Beardwell CG. Radiation and hypothalamic-pituitary function. Baillieres Clin Endocrinol Metab 1990;4:147-175.
4. Chieng PU, Huang TS, Chang CC, Chong PN, Tien RD, Su CT. Reduced hypothalamic blood flow after radiation treatment for nasopharyngeal cancer: SPECT studies in 34 patients. AJNR Am J Neuroradiol 1991;12:661-665.
5. Lowry WS. Late effects of pituitary irradiation [letter]. N Engl J Med 1970;283:658.
6. Shalet SM. Disorders of the endocrine system due to radiation and cytotoric chemotherapy. Clin Endocrinol 1983;18:637-659.
7. Shalet SM, Beardwell CG, Morris-Jones PH, Pearson D. Pituitary function after treatment of intracranial tumours in children. Lancet 1975;i:104-107.
8. Robison LL, Nesbit ME Jr, Sather HN, Meadows AT, Ortega JA, Hammond GD. Height of children successfully treated for acute lymphoblastic leukemia: a report from the late effects study committee of childrens cancer study group. Med Pediatr Oncol 1985;13:14-21.
9. Clayton PE, Shalet SM, Morris-Jones PH, Price DA. Growth in children treated for acute lymphoblastic leukemia. Lancet 1988;i:460-462.
10. Harrop JS, Davies TJ, Capra LG, Marks V. Hypothalamic-pituitary function following successful treatment of intracranial tumors. Clin Endocrinol 1976;5:313-321.
11. Perry-Keene DA, Connelly JF, Young RA, Wettenhall HNB, Martin FIR. Hypothalamic hypopituitarism following external radiotherapy for tumours distant from the adenohypophysis. Clin Endocrinol 1976;5:373-380.
12. Littley MD, Shalet SM, Beardwell CG, Robinson EL, Sutton ML. Radiation induced hypopituitarism is dose-dependent. Clin Endocrinol 1989;31:363-373.
13. Taphoorn MJB, Heimans JJ, Van der Veen EA, Karim ABMF. Endocrine function in long-term survivors of low-grade supratentorial glioma treated with radiation therapy. J Neurooncol 1995;25:97-102.
14. Constine LS, Woolf PD, Cann D, et al. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med 1993;328:87-94.
15. Livesey EA, Brook CGD. Thyroid dysfunction after radiotherapy and chemotherapy for brain tumors. Arch Dis Child 1989;64:593-595.
16. Mechanick JI, Hochberg FH, LaRocque A. Hypothalamic dysfunction following whole-brain irradiation. J Neurosurg 1986;65:490-494.
17. Constine LS, Rubin P, Woolf PD, Doane K, Lash CM. Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies. J Clin Oncol 1987;5:1841-1851.
18. Petterson T, Macfarlane IA, Foy PH, Hughes HJ, Jones B, Shaw D. Hyperprolactinaemia and infertility following cranial irradiation for brain tumours: successful treatment with bromocriptine. Br J Neurosurg 1993;7:571-574.
19. Livesey EA, Brook CGD. Gonadal dysfunction after treatment of intracranial tumors. Arch Dis Child 1989;64:593-595.
20. Huang K. Assessment of hypothalamic-pituitary function in women after external head irradiation. J Clin Endocrinol Metab 1979;49:623-627.
21. Hall JE, Martin KA, Whitney HA, Landy H, Crowley WF Jr. Potential for fertility with replacement of hypothalamic gonadotropin-releasing hormone in long-term survivors of cranial tumors. J Clin Endocrinol Metab 1994;79:1166-1172.
22. Lendon M, Kann IM, Palmer MK, Shalet SM, Morris-Jones PH. Testicular histology after combination chemotherapy in childhood for acute lymphoblastic leukemia. Lancet 1978;2-439-441.
23. Ambrosi B, Bodicchio D, Peverelli S, Ferrasio P, Faglia G. Value of serum dehydroepiandrosterone sulfate assay in the evaluation of pituitary-adrenal insufficiency after pituitary adenomectomy. J Endocrinol Invest 1992;15:827-835.
24. Tordjman K, Trostanetsky Y, Limor R, Stern N. The 1 μg ACTH test is more accurate than the standard 250 μg ACTH stimulation in patients with pituitary diseases [abstract]. In: Program and abstracts. San Francisco: The Endocrine Society, 1996:51.
25. Arnold A. Effects of X-irradiation on the hypothalamus. J Clin Endocrinol 1954;14:859-868.
26. Wigg DR, Murray RML, Koschel K. Tolerance of the central nervous system to photon irradiation. Endocrine complications. Acta Radiol Oncol 1982;21:49-60.
27. Littley MD, Shalet SM, Beardwell CG, Ahmed SR, Applegate G, Sutton ML. Hypopituitarism following external radiotherapy for pituitary tumours in adults. Q J Med 1989;70:145160.
28. Shalet SM, Beardwell CG, Pearson D, Jones PH. The effect of varying doses of cerebral irradiation on growth hormone production in childhood. Clin Endocrinol 1976;5:287-290.
29. Clayton PE, Shalet SM. Dose dependency of time of onset of radiation-induced growth hormone deficiency. J Pediatr 1991;118:226-228.
30. Richards GE, Wara WM, Grumbach MM, Kaplan SL, Sheline GE, Conte FA. Delayed onset of hypopituitarism: sequelae of therapeutic irradiation of central nervous system, eye and middle ear tumors. J Pediatr 1976;89:553-559.
31. Danoff BF, Cowchock FS, Marquette C, Mulgrew L, Kramer S. Assessment of the long-term effects of primary radiation therapy for brain tumors in children. Cancer 1982;49:1580-1586.
32. Mostow EN, Byrne J, Connelly RR, Mulvihill JJ. Quality of life in long-term survivors of CNS tumors of childhood and adolescence. J Clin Oncol 1991;9:592-599.
33. Taphoorn MJB, Heimans JJ, Snoek FJ, et al. Assessment of quality of life in patients treated for low-grade glioma: a preliminary report. J Neurol Neurosurg Psychiatry 1992;55:372-376.