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Volumn 21, Issue 5, 1997, Pages 873-883

U-95666E: A potential anti-parkinsonian drug with anxiolytic activity

Author keywords

Cerebellar cGMP; Dopamine agonists; Parkinson's disease; Striatal acetylcholine

Indexed keywords

ACETYLCHOLINE; ANTIPARKINSON AGENT; ANXIOLYTIC AGENT; APOMORPHINE; BROMOCRIPTINE; CYCLIC GMP; DOPAMINE 2 RECEPTOR STIMULATING AGENT; PERGOLIDE; PRAMIPEXOLE; RACLOPRIDE; RESERPINE; U 95666E; UNCLASSIFIED DRUG;

EID: 0030748465     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(97)00086-9     Document Type: Article
Times cited : (23)

References (25)
  • 2
    • 0021915417 scopus 로고
    • The benzodiazepine antagonist RO 15 1788 reverses the effect of methy-β-carboline-3-carboxylate but not of harmaline on cerebellar cGMP and motor performance in mice
    • BURKARD, W. P., BONETTI, E. P. and HAEFELY, W. (1985) The benzodiazepine antagonist RO 15 1788 reverses the effect of methy-β-carboline-3-carboxylate but not of harmaline on cerebellar cGMP and motor performance in mice. Eur. J. Pharmacal. 109:241-247.
    • (1985) Eur. J. Pharmacal. , vol.109 , pp. 241-247
    • Burkard, W.P.1    Bonetti, E.P.2    Haefely, W.3
  • 4
    • 0023757877 scopus 로고
    • Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen
    • DAWSON, V. L., DAWSON, T. M., FILLOUX, F. M. and WAMSLEY, J. K. (1988) Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen. Life Sci. 42: 1933-1939.
    • (1988) Life Sci. , vol.42 , pp. 1933-1939
    • Dawson, V.L.1    Dawson, T.M.2    Filloux, F.M.3    Wamsley, J.K.4
  • 5
    • 0029875739 scopus 로고    scopus 로고
    • Behavioral effects in the rats of the putative Dopamine D-3 receptor agonist 7-OH-DPAT comparison with quinpirole and apomorphine
    • DEPOORTERE, R., PERRAULT, G. and SANGER, D. J. (1996) Behavioral effects in the rats of the putative Dopamine D-3 receptor agonist 7-OH-DPAT comparison with quinpirole and apomorphine. Psychopharmacol. 124: 231-240.
    • (1996) Psychopharmacol. , vol.124 , pp. 231-240
    • Depoortere, R.1    Perrault, G.2    Sanger, D.J.3
  • 6
    • 0021671859 scopus 로고
    • Acetylcholine measurement by high pressure liquid chromatography using an enzyme-loaded post-column reactor
    • EVA, C., HADJICONSTANTINOU, M., NEFF. N. H. and MEEK, J. L. (1984) Acetylcholine measurement by high pressure liquid chromatography using an enzyme-loaded post-column reactor. Anal. Biochem. 143: 320-324.
    • (1984) Anal. Biochem. , vol.143 , pp. 320-324
    • Eva, C.1    Hadjiconstantinou, M.2    Neff, N.H.3    Meek, J.L.4
  • 8
    • 0023263919 scopus 로고
    • Biochemical pathophysiology of Parkinson's disease
    • HORNYKIEWICZ, O. and KISH, S. J. (1986) Biochemical pathophysiology of Parkinson's disease. Adv. Neurol. 45: 19-34.
    • (1986) Adv. Neurol. , vol.45 , pp. 19-34
    • Hornykiewicz, O.1    Kish, S.J.2
  • 9
    • 0029269229 scopus 로고
    • The rationale for the use of dopamine agonists in Parkinson's disease
    • JENNER, P. (1995) The rationale for the use of dopamine agonists in Parkinson's disease. Neurology 45: S6-S12.
    • (1995) Neurology , vol.45
    • Jenner, P.1
  • 10
    • 0028004353 scopus 로고
    • D2 dopamine receptor mRNA distribution in cholinergic and somatostatinergic cells of rat caudate-putamen and nucleus accumbens
    • MacLENNAN, A. J., LEE, N., VINCENT, S. R. and WALKER, D. W. (1994) D2 dopamine receptor mRNA distribution in cholinergic and somatostatinergic cells of rat caudate-putamen and nucleus accumbens. Neurosci. Lett. 180: 214-218.
    • (1994) Neurosci. Lett. , vol.180 , pp. 214-218
    • MacLennan, A.J.1    Lee, N.2    Vincent, S.R.3    Walker, D.W.4
  • 11
    • 0017344150 scopus 로고
    • Success and problems of long-term therapy in Parkinson's disease
    • MARSDEN, C. D. and PARKES, J. D. (1977) Success and problems of long-term therapy in Parkinson's disease. Lancet 2: 345-49.
    • (1977) Lancet , vol.2 , pp. 345-349
    • Marsden, C.D.1    Parkes, J.D.2
  • 12
    • 0027489476 scopus 로고
    • Parkinson's disease and anxiety: Comorbidity with depression
    • MENZA, M. A., ROBERTSON-HOFFMAN, D. E. and BONAPACE, A. E. (1993) Parkinson's disease and anxiety: comorbidity with depression. Biol. Psychiat. 34: 465-470.
    • (1993) Biol. Psychiat. , vol.34 , pp. 465-470
    • Menza, M.A.1    Robertson-Hoffman, D.E.2    Bonapace, A.E.3
  • 14
    • 0011075707 scopus 로고
    • Induction of oral dyskinesias in naive rats by D1 receptor stimulation
    • ROSENGARTEN, H., SCHWEITZER, J. W. and FRIEDHOFF, A. J. (1983) Induction of oral dyskinesias in naive rats by D1 receptor stimulation. Life Sci. 39: 29-35.
    • (1983) Life Sci. , vol.39 , pp. 29-35
    • Rosengarten, H.1    Schweitzer, J.W.2    Friedhoff, A.J.3
  • 15
    • 0020041211 scopus 로고
    • Effect of dopamine agonists and neuroleptic agents on striatal acetylcholine transmission in the rat: Evidence against dopamine receptor multiplicity
    • SCATTON, B. (1982) Effect of dopamine agonists and neuroleptic agents on striatal acetylcholine transmission in the rat: evidence against dopamine receptor multiplicity. J. Pharmacal. Exp. Ther. 220: 197-202.
    • (1982) J. Pharmacal. Exp. Ther. , vol.220 , pp. 197-202
    • Scatton, B.1
  • 16
    • 0022607210 scopus 로고
    • Zolpidem, a novel nonbenzodiazepine hypnotic, II. Effect on cerebellar cGMP levels and cerebral monoamines
    • SCATTON, B., CLAUSTRE, Y., DENNIS, T. and NISHIKAWA, T. (1986) Zolpidem, a novel nonbenzodiazepine hypnotic, II. Effect on cerebellar cGMP levels and cerebral monoamines. J. Pharmacol. Exp. Ther. 237: 659-665.
    • (1986) J. Pharmacol. Exp. Ther. , vol.237 , pp. 659-665
    • Scatton, B.1    Claustre, Y.2    Dennis, T.3    Nishikawa, T.4
  • 17
    • 0023762217 scopus 로고
    • Regulation of brain acetylcholine concentration by muscarinic receptors
    • SETHY, V. H. and FRANCIS, J. W. (1988) Regulation of brain acetylcholine concentration by muscarinic receptors. J. Pharmacol. Exp. Ther. 246:243-248.
    • (1988) J. Pharmacol. Exp. Ther. , vol.246 , pp. 243-248
    • Sethy, V.H.1    Francis, J.W.2
  • 18
    • 0023191876 scopus 로고
    • Onset and duration of action of benzodiazepines as determined by inhibition of [3H]-flunitrazepam binding
    • SETHY, V. H., FRANCIS, J. W. and ELFRING, G. (1987) Onset and duration of action of benzodiazepines as determined by inhibition of [3H]-flunitrazepam binding. Drug Dev. Res. 10: 117-121.
    • (1987) Drug Dev. Res. , vol.10 , pp. 117-121
    • Sethy, V.H.1    Francis, J.W.2    Elfring, G.3
  • 19
    • 0025830796 scopus 로고
    • Role of cGMP in the mechanism of anxiolytic activity of U-78875
    • SETHY, V. H. and OIEN, T. T. (1991) Role of cGMP in the mechanism of anxiolytic activity of U-78875. Pharmacol. Biochem. Behav. 39: 379-382.
    • (1991) Pharmacol. Biochem. Behav. , vol.39 , pp. 379-382
    • Sethy, V.H.1    Oien, T.T.2
  • 20
    • 0016345077 scopus 로고
    • Regulation of striatal acetylcholine concentration by dopamine receptor
    • SETHY, V. H. and Van WOERT, M. (1974) Regulation of striatal acetylcholine concentration by dopamine receptor. Nature 251: 529-530.
    • (1974) Nature , vol.251 , pp. 529-530
    • Sethy, V.H.1    Van Woert, M.2
  • 21
    • 0027445442 scopus 로고
    • Anxiety and motor performance in Parkinson's disease
    • SIEMERS, E. R., SHEKHAR, A., QUAID, K. and DICKSON, H. (1993) Anxiety and motor performance in Parkinson's disease. Mov. Disord. 8: 501-506.
    • (1993) Mov. Disord. , vol.8 , pp. 501-506
    • Siemers, E.R.1    Shekhar, A.2    Quaid, K.3    Dickson, H.4
  • 22
    • 0025095632 scopus 로고
    • Anxiety disorders in patient with Parkinson's disease
    • STEIN, M. S., HEUSER, I. J., JUNCOS, J. L. and Uhde T. W. (1990) Anxiety disorders in patient with Parkinson's disease. Am. J. Psychiat. 147: 217-220.
    • (1990) Am. J. Psychiat. , vol.147 , pp. 217-220
    • Stein, M.S.1    Heuser, I.J.2    Juncos, J.L.3    Uhde, T.W.4
  • 24
    • 0020646296 scopus 로고
    • 2 dopamine agonist, increases acetylcholine concentration in rat corpus striatum
    • 2 dopamine agonist, increases acetylcholine concentration in rat corpus striatum. J. Pharm. Pharmacol. 35: 328-329.
    • (1983) J. Pharm. Pharmacol. , vol.35 , pp. 328-329
    • Wong, D.T.1    Bymaster, F.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.