6-Thio-2'-deoxyinosine: Synthesis, incorporation, and evaluation as a postsynthetically modifiable base in oligonucleotides

Tetrahedron

Volumn 53, Issue 32, 1997, Pages 11191-11202

  Coleman, Robert S ^a,b   Arthur, John C ^b   McCary, Jason L ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 THIO 2' DEOXYINOSINE DERIVATIVE; INOSINE DERIVATIVE; OLIGODEOXYNUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; PRIORITY JOURNAL; REACTION ANALYSIS; THERMAL ANALYSIS;

EID: 0030748434     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00376-1     Document Type: Article

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47. For the origin and design of this side-chain, see reference 3.
48. All synthetic and post-synthetically modified oligonucleotides were prepared as described in the Experimental Section, and were purified by RP-HPLC to homogeneity.