Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels

Biochemical Pharmacology

Volumn 54, Issue 1, 1997, Pages 133-141

  Cabell, Karen S ^a   Ma, Lin ^a   Johnson, Peter ^a,b  

^a OHIO UNIVERSITY   (United States)

^b OHIO UNIVERSITY   (United States)

Author keywords

Antioxidant enzymes; Captopril; Hydralazine; Lipid peroxidation; Myocardium; SHR rat; Terazosin

Indexed keywords

ANTIHYPERTENSIVE AGENT; CAPTOPRIL; CAPTOPRIL PLUS HYDROCHLOROTHIAZIDE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; HYDRALAZINE; MANGANESE SUPEROXIDE DISMUTASE; TERAZOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE; HYPERTENSION; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BODY WEIGHT; CAPTOPRIL; ENZYME ACTIVATION; HEART; HYDRALAZINE; LIPID PEROXIDATION; LIVER; MUSCLE, SKELETAL; MYOCARDIUM; PRAZOSIN; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0030748097     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00161-5     Document Type: Article

References (46)

1. Halliwell B and Gutteridge JMC, Free Radicals in Biology and Medicine, 2nd Edn. Oxford University Press, Oxford, 1989.
2. Wispe JR, Warner BB, Clark JC, Dey CR, Neuman J, Glasser SW, Crapo JD, Chang LY and Whitsett JA, Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. J Biol Chem 267: 23937-23941, 1992.
3. Jaruga P, Zastawny TH, Skokowski J, Dizdaroglu M and Olinski R, Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer. FEBS Lett 341: 59-64, 1994.
4. Quinlan T, Spivack S and Mossman BT, Regulation of antioxidant enzymes in lung after oxidant injury. Environ Health Perspect 102 (Suppl 2): 79-87, 1994.
5. Clerch LB, A 3′ untranslated region of catalase mRNA composed of a stem-loop and dinucleotide repeat elements binds to a 69-kDa redox-sensitive protein. Arch Biochem Biophys 317: 267-274, 1995.
6. Ito H, Torii M and Suzuki T, A comparative study on defense systems for lipid peroxidation by free radicals in spontaneously hypertensive and normotensive rat myocardium. Comp Biochem Physiol 103B: 37-40, 1992.
7. Uotila J, Tuimala R, Pykko K and Ahotupa M, Pregnancy-induced hypertension is associated with changes in maternal and umbilical blood antioxidants. Gynecol Obstet Invest 6: 153-157, 1993.
8. Turrens JF, Thornton J, Barnard ML, Snyder S, Liu G and Downey JM, Protection from reperfusion injury by preconditioning hearts does not involve increased antioxidant defenses. Am J Physiol 62: H585-H589, 1992.
9. Hong H and Johnson P, Antioxidant enzyme activities and lipid peroxidation levels in exercised and hypertensive rat tissues. Int J Biochem Cell Biol 27: 923-931, 1995.
10. Schoenberger JA, Antihypertensive drug therapy and coronary heart disease risk. J Fam Pract 36: 70-84, 1992.
11. Lemke LE and McQueen CA, Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine. Drug Metab Dispos 23: 559-565, 1995.
12. van Zwieten PA, New avenues in antihypertensive drug treatment. Clin Exp Hypertens 15: 1205-1220, 1993.
13. Mira ML, Silva MM, Queiroz MJ and Manso CF, Angiotensin converting enzyme inhibitors as oxygen free radical scavengers. Free Radic Res Commun 19: 173-181, 1993.
14. Aruoma OJ, Characterization of drugs as antioxidant prophylactics. Free Radic Biol Med 20: 675-705, 1996.
15. Vulpis V, Roncali L, Bertossi M, Nico B, Seccia T, Ricci S and Pirrelli A, Left-ventricular hypertrophy in the spontaneously hypertensive rat: Effect of ACE inhibitors on ultrastructural morphology. Cardiology 84: 14-24, 1994.
16. Takeda N, Tanamura A, Iwai T, Kato M, Noma K and Nagano M, Beneficial effect of ACE inhibitor in congestive heart failure. Mol Cell Biochem 129: 139-143, 1993.
17. Engelman RM, Rousou JA, Iyengar J and Das DK, Captopril, an ACE inhibitor for optimizing reperfusion after acute myocardial infarction. Ann Thorac Surg 52: 918-926, 1991.
18. Sogaard P, Klausen IC, Rungby J, Faergeman O and Thygesen K, Lipoprotein(a) and oxygen free radicals in survivors of acute myocardial infarction: Effects of captopril. Cardiology 87: 18-22, 1996.
19. Lapenna D and Cuccurullo F, Captopril: Does it act as a direct antioxidant by free radical scavenging in humans? Free Radic Biol Med 18: 377-378, 1995.
20. Schneider R, Iscovitz H, Ilan Z, Bernstein K, Gros M and Iaina A, Oxygen free radical scavenger system intermediates in essential hypertensive patients before and immediately after sublingual captopril administration. Isr J Med Sci 26: 491-495, 1990.
21. de Cavanagh EMV, Inserra F, Ferder L, Romano L, Ercole L and Fraga CG, Superoxide dismutase and glutathione peroxidase activities are increased by enalapril and captopril in mouse liver. FEBS Lett 361: 22-24, 1995.
22. Glowacki A, Kucharz EJ and Olczyk K, Glycosaminoglycan -collagen interactions in vitro in the hydralazine-induced collagen-like syndrome. Acta Biochim Pol 40: 182-185, 1993.
23. Martelli A, Allavena A, Campart GB, Canonero R, Ghia M, Mattioli F, Mereto E, Robbiano L and Brambilla G, In vitro and in vivo testing of hydralazine genotoxicity. J Pharmacol Exp Ther 273: 113-120, 1995.
24. Weglarz L, Drodz M, Wardas M and Goss M, Activities of antioxidant enzymes in fibroblasts cultured in vitro in the presence of hydralazine. Biomed Biochim Acta 48: 489-493, 1989.
25. Cohen J, Long-term efficacy and safety of terazosin. J Clin Pharmocol 33: 272-278, 1993.
26. Somberg J, Ehrenpreis S, Shroff G and Koshla S, Risk factors not addressed in antihypertensive therapy based solely on blood pressure control. J Clin Pharmacol 33: 279-285, 1993.
27. Mukherjee D and Sen S, Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats. Circ Res 67: 1474-1480, 1990.
28. 1-adrenoceptor blockade on the development of hypertension in the spontaneously hypertensive rat. Eur J Pharmacol 211: 263-268, 1992.
29. Alden SM, Pierce RA, Tozzi CA, Mackenzie JW, Deak SB and Boyd CD, Changes in aortic levels of tropoelastin mRNA following treatment of rats with the antihypertensive drugs captopril and hydralazine. J Surg Res 51: 491-494, 1991.
30. Criswell D, Powers S, Dodd S, Lawler J, Edwards W, Renshler K and Grinton S, High intensity training-induced changes in skeletal muscle antioxidant enzyme activity. Med Sci Sports Exerc 25: 1135-1140, 1993.
31. Crapo DJ, McCord JM and Fridovich I, Preparation and assay of superoxide dismutase. Methods Enzymol 53: 382-393, 1978.
32. Paoletti F and Mocali A, Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation. Methods Enzymol 186: 209-220, 1990.
33. Aebi H, Catalase in vitro. Methods Enzymol 105: 121-126, 1984.
34. Flohe L and Gunzler WF, Assays of glutathione peroxidase. Methods Enzymol 105: 114-121, 1984.
35. Philips N, Bashey RI and Jimenez SA, Collagen and fibronectin expression in cardiac fibroblasts from hypertensive rats. Cardiovosc Res 28: 1342-1347, 1994.
36. Yagi K, A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 15: 212-216, 1976.
37. Draper HH and Hadley M, Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 186: 421-431, 1990.
38. Schumacher MM, Physicians' Desk Reference, 47th Edn. Medical Economics Data, Montvale, NJ, 1993.
39. Hammeren J, Powers S, Lawler J, Criswell D, Martin D, Lowenthal D and Pollock M, Exercise training-induced alterations in skeletal muscle oxidative and antioxidant enzyme activity in senescent rats. Int J Sports Med 13: 412-416, 1992.
40. Powers SK, Criswell D, Lawler J, Ji LL, Martin D, Herb RA and Dudley GA, Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle. Am J Physiol 266: R375-R380, 1994.
41. Leeuwenburgh C, Fiebig R, Chandwaney R and Ji LL, Aging and exercise in skeletal muscle: Responses of glutathione and antioxidant enzyme systems. Am J Physiol 267: R439-R445, 1994.
42. Wohaieb SA and Godin DV, Starvation-related alterations in free radical tissue defense mechanisms in rats. Diabetes 36: 169-173, 1987.
43. Ho Y-S, Dey MS and Crapo JD, Antioxidant enzyme expression in rat lungs during hyperoxia. Am J Physiol 270: L810-L818, 1996.
44. Chen Y and Frank L, Differential gene expression of antioxidant enzymes in the perinatal rat lung. Pediatr Res 34: 27-31, 1993.
45. Iwai N, Hanai K, Tooyama I, Kitamura Y and Kinoshita M, Regulation of neuronal nitric oxide synthase in rat adrenal medulla. Hypertension 25: 431-436, 1995.
46. Katayama S, Abe M, Inaba M, Itabashi A and Ishii J, Effects of captopril or nitrendipine in left ventricular collagen or laminin B2 gene expression. Jpn Heart J 34: 773-783, 1993.