The participation of the Fas-mediated cytotoxic pathway by natural killer cells is tumor-cell-dependent

Cancer Immunology Immunotherapy

Volumn 44, Issue 5, 1997, Pages 282-290

  Mori, Shunsuke ^a   Jewett, Anahid ^a   Murakami Mori, Kaoru ^b   Cavalcanti, Marta ^a   Bonavida, Benjamin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HUNTINGTON MEMORIAL HOSPITAL   (United States)

Author keywords

Fas ligand; Interferon ; Killing mechanism; NK cells; Perforin

Indexed keywords

ALPHA INTERFERON; EGTAZIC ACID; FAS ANTIGEN; GRANZYME A; GRANZYME B; INTERLEUKIN 12; INTERLEUKIN 2; MAGNESIUM ION; PERFORIN;

ARTICLE; CELL STRAIN HT29; CHROMIUM 51 RELEASE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CYTOTOXICITY, IMMUNOLOGIC; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION; GRANZYMES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HT29 CELLS; HUMANS; INTERFERON-ALPHA; INTERLEUKIN-12; JURKAT CELLS; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0030747564     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050384     Document Type: Article

References (30)

1. Anel A, Richieri GV, Kleinfeld AM (1994) A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation. J Biol Chem 269:9506
2. Arase H, Arase N, Saito T (1995) Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 181:1235
3. Berke G, Rosen D, Ronen D (1993) Mechanism of lymphocyte-mediated cytolysis: functional cytolytic T cells lacking perforin and granzymes. Immunology 78:105
4. Bradley MJ, Nagarkatti P, Nagarkatti M (1996) Fas ligand is not critical for spontaneous and IL-2 induced Iytic activity by NK cells: evidence from Fas ligand-mutated gld mice. Proc Natl Assoc Cancer Res 37:458
5. Braun MY, Lowin B, French L, Acha-Orbea H, Tschopp J (1996) Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease. J Exp Med 183:657
6. Eischen CM, Schilling JD, Lynch DH, Krammer PH, Leibson PJ (1996) Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis. J Immunol 156:2693
7. Gershenfeld HK, Hershberger RJ, Shows TB, Weissman IL (1988) Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell specific trypsin-like serine protease. Proc Natl Acad Sci USA 85:1184
8. Graubert TA, Ley TL (1996) How do lymphocytes kill tumor cells? Clin Cancer Res 2:785
9. Hanabuchi S, Koyanagi M, Kawasaki A, Shinohara N, Matsuzawa A, Nishimura Y, Kobayashi Y, Yonehara S, Yagita H, Okumura K (1994) Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci USA 91:4930
10. Hayes MP, Berrebi GA, Henkart PA (1989) Induction of target cell DNA release by the f cytotoxic T lymphocyte granule protease granzyme A. J Exp Med 170:933
11. Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ (1994) Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76:977
12. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S-I, Sameshima M, Hase A, Seto Y, Nagata S (1991) The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233
13. Kagi D, Ledermann B, Bürki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H (1994) Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369:31
14. Kagi D, Vignaux F, Ledermann B, Burki K, Depraetere V, Nagata S, Hengartner H, Golstein P (1994) Fas and perform pathways as major mechanisms of T-cell mediated cytotoxicity. Science 265:528
15. Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, Yagita h (1995) Metalloproteinase-mediated release of human Fas ligand. J Exp Med 182:1777
16. Lichtenheld MG, Olsen KJ, Liu P, Lowrey DM, Hameed A, Hengartner H, Podack ER (1988) Structure and function of human perform. Nature 335:448
17. Lowin B, Hahne M, Mattmann C, Tschopp J (1994) Cytolytic T-cell cytotoxicity is mediated through perform and Fas Iytic pathway. Nature 370:6501
18. Lowin B, Mattman C, Hahne M, Tschopp J (1996) Comparison of Fas (Apo-1/CD95)-and perforin-mediated cytotoxicity in primary T lymphocytes. Int Immunol 8:57
19. Montel AH, Bochan MR, Hobbs JA, Lynch DH, Brahmi Z (1995) Fas involvement in cytotoxicity mediated by human NK cells. Cell Immunol 166:236
20. Nakajima-Iijima S, Hamada H, Reddy P, Kakunaga T (1985) Molecular structure of the human cytoplasmic β-actin gene: interspecies homology of sequences in the introns. Proc Natl Acad Sci USA 82:6133
21. Ostergaard HL, Kane KP, Mescher MF, Clark WR (1987) Cytotoxic T lymphocyte mediated lysis without release of serine esterase. Nature 330:71
22. Ozes ON, Reiter Z, Klein S, Blatt LM, Taylor MW (1992) A comparison of interferon-Con 1 with natural recombinant interferons-α: antiviral, antiproliferative, and natural-killer-inducing activities. J Interferon Res 12:55
23. Podack ER, Hengartner H, Lichtenheld MG (1991) A central role of perforin in cytolysis? Annu Rev Immunol 9: 129
24. 2+-independent T cell-mediated cytotoxicity. J Exp Med 177:195
25. Schmid J, Weissman C (1987) Induction of mRNA for a serine protease and a β-thromboglobulin-like protein in mitogen-stimulated human leukocytes. J Immunol 139:250
26. Suda T, Takahashi T, Golstein P, Nagata S (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169
27. Takahashi T, Tanaka M, Inazawa J, Abe T, Suda T, Nagata S (1994) Human Fas ligand: gene structure, chromosomal location and species specificity. Int Immunol 6:1567
28. Tanaka M, Suda T, Haze K, Nakamura N, Sato K, Kimura F, Motoyoshi K, Mizuki M, Tagawa S, Ohga S, Hatake K, Drummond AH, Nagata S (1996) Fas ligand in human serum. Nature Med 2:317
29. Yonehara S, Ishii A, Yonehara M (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747
30. Yonehara S, Mshimura Y, Kishi S. Yonehara M, Takazawa K, Tamatani T, Ishi A (1994) Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes. Int Immunol 12:1849