Effect of dosing vehicle on the hepatotoxdcbty of CCl4 and nephrotoxicity of CHCl3 in rats

Journal of Toxicology and Environmental Health

Volumn 51, Issue 5, 1997, Pages 463-476

  Raymond, Pierre ^a   Plaa, Gabriel L ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CORN OIL; DRUG VEHICLE; POLYSORBATE; RICINOMACROGOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; CONTROLLED STUDY; DOSE RESPONSE; FEEDING; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SUSPENSION; TOXICITY TESTING;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; CARBON TETRACHLORIDE; CARCINOGENS; CHLOROFORM; CORN OIL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; KIDNEY; LIVER; MALE; P-AMINOHIPPURIC ACID; PLANT OILS; POLYSORBATES; RATS; RATS, SPRAGUE-DAWLEY; VEHICLES;

ANIMALIA; ZEA MAYS;

EID: 0030747505     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/00984109708984037     Document Type: Article

References (31)

1. Bull, R. J., Brown, J. M., Meierhenry, E. A., Jorgenson, T. A., Robinson, M. and Stober, J. A. 1986. Enhancement of the hepatotoxicity of chloroform in B6C3F1 mice by corn oil: Implications for chloroform carcinogenesis. Environ. Health Perspect. 69:49-58.
2. 4-induced liver injury. Toxicol. Lett. 57:47-54.
3. Chieco, P., Moslen, M. T. and Reynolds, E. S. 1981. Effect of administrative vehicle on oral 1,1-dichloroethylene toxicity. Toxicol. Appt. Pharmacol. 57:146-155.
4. Condie, L. W., Laurie, R. D., Mills, T., Robinson, M. and Bercz, J. P. 1986. Effect of gavage vehicle on hepatotoxicity of carbon tetrachloride in CD-1 mice: Corn oil versus Tween-60 aqueous emulsion. Fundam. Appl. Toxicol. 7:199-206.
5. Cross, R. J. and Taggart, J. 1950. Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices. Am. J. Physiol. 161:181-190.
6. Dozier, M. M., Ratajczak, H. V., Sothern, R. B. and Thomas, P. T. 1996. The influence of vehicle gavage on seasonality of immune system parameters in the B6C3F1 mouse. Fundam. Appl. Toxicol. Supp. Toxicologist 30:1776.
7. Dupont, J., White, P. J., Carpenter, M. P., Schaefer, E. J., Meydani, S. N., Elson, C. E., Woods, M. and Gorbach, S. L. 1990. Food uses and health effects of corn oil. J. Am. Coll. Nutr. 9:438-470.
8. Farooqui, M. Y. H., Ybarra, B., Piper, J. and Tamez, A. 1995. Effect of dosing vehicle on the toxicity and metabolism of unsaturated aliphatic nitriles. J. Appl. Toxicol. 15:411-420.
9. Finney, D. J. 1971. Probit analysis, 3rd ed. Cambridge: Cambridge University Press.
10. Hewitt, W. R., Miyajima, H., Côté, M. G. and Plaa, G. L. 1980. Acute alteration of chloroform-induced hepato- and nephrotoxicity by n-hexane, methyl n-butyl ketone, and 2,5-hexane-dione. Toxicol. Appl. Pharmacol. 53:230-248.
11. Iritani, N., Fukada, E. and Kitamura, Y. 1980. Effect of corn oil feeding on lipid peroxidation in rats. I. Nutr. 110:924-930.
12. Jorgenson, T. A., Meierhenry, E. F., Rushbrook, C. J., Bull, R. J. and Robinson, M. 1985. Carcinogenicity of chloroform in drinking water to male Osborne-Mendel rats and female B6C3F1 mice. Fundam. Appl. Toxicol. 5:760-769.
13. Kim, H. J., Bruckner, J. V., Dallas, C. E. and Gallo, J. M. 1990a. Effect of dosing vehicles on the pharmacokinetics of orally administered carbon tetrachloride in rats. Toxicol. Appl. Pharmacol. 102:50-60.
14. Kim, H. J., Odend'hal, S. and Bruckner, J. V. 1990b. Effect of oral dosing vehicles on the acute hepatotoxicity of carbon tetrachloride in rats. Toxicol. Appl. Pharmacol. 102:34-49.
15. Klaunig, J. E., Ruch, R. J. and Pereira, M. A. 1986. Carcinogenicity of chlorinated methane and ethane compounds administered in drinking water to mice. Environ. Health Perspect. 69:89-95.
16. Koporec, K. P., Kim, H. J., Mackenzie, W. F. and Bruckner, J. V. 1995. Effect of oral dosing vehicles on the subchronic hepatotoxicity of carbon tetrachloride in the rat. J. Toxicol. Environ. Health 44:13-27.
17. Lilly, P. D., Simmons, J. E. and Pegram, R. A. 1994. Dose-dependent vehicle differences in the acute toxicity of bromodichloromethane. Fundam. Appl. Toxicol. 23:132-140.
18. Lilly, P. D., Simmons, J. E. and Pegram, R. A. 1996. Effect of subchronic corn oil gavage on the acute toxicity of orally administered bromodichloromethane. Toxicol. Lett. 87:93-102.
19. Merrick, B. A., Robinson, M. and Condie, L. W. 1989. Differing hepatotoxicity and lethality after subacute trichloroethylene exposure in aqueous or corn oil gavage vehicle in B6C3F1 mice. J. Appl. Toxicol. 8:15-21.
20. Moore, D. H., Chasseaud, L. F., Majeed, S. K., Prentice, D. E. and Roe, F. J. C. 1982. The effect of dose and vehicle on early tissue damage and regenerative activity after chloroform administration to mice. Fundam. Chem. Toxicol. 20:951-954.
21. National Cancer Institute. 1976. Carcinogenesis Bioassay of Chloroform. NTIS no. PB264018/AS. Washington, DC: NCI.
22. Recknagel, R. O., Glende, E. A. and Britton, R. S. 1991. Free radical damage and lipid peroxidation. In Hepatotoxicology, eds. R. G. Meeks, S. D. Harrison, and R. J. Bull, pp. 401-436. Boca Raton, FL: CRC Press.
23. Reitman, S. and Frankel, S. 1957. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28:56-63.
24. Shertzer, H. G. and Tabor, W. M. 1985. Peroxide removal from organic solvents and vegetable oils. J. Environ. Sci. Health A20:845-855.
25. Shibayama, Y. 1992. Hepatotoxicity of heated and oxygenated corn oil. Exp. Toxicol. Pathol. 44:255-258.
26. Simmons, J. E., McDonald, A., Seely, J. C. and Sey, Y. M. 1996. Examination of the effect of gavage vehicle on carbon tetrachloride hepatotoxicity in F-344 rats. Fundam. Appl. Toxicol. Suppl. Toxicologist 30:431.
27. Takahashi, H., Johansson, I., French, S. W. and Ingelman-Sundberg, M. 1992. Effect of dietary fat composition activities of the microsomal ethanol oxidizing system and ethanol-inducible cytochrome P450 (CYP2E1) in the liver of rats chronically fed ethanol. Pharmacol. Toxicol. 70:347-352.
28. Williams, R. J. and Black, R. K. 1993. Effect of oral dosing vehicle on the blood to air partition coefficient. Toxicologist 13:1419.
29. Withey, J. R., Collins, B. T. and Collins, P. G. 1983. Effect of vehicle on the pharmacokinetics and uptake of four halogenated hydrocarbons from the gastrointestinal tract of the rat. J. Appl. Toxicol. 3:249-253.
30. Yoo, J.-S. H., Hong, J. Y., Ning, S. M. and Yang, C. S. 1990. Roles of dietary corn oil in the regulation of cytochrome P450 and glutathione 5-transferase in rat liver. J. Nutr. 120:1718-1726.
31. Yoo, J.-S. H., Ning, S. M., Pantuck, C. B., Pantuck, E. J. and Yang, C. S. 1991. Regulation of hepatic microsomal cytochrome P450IIE1 level by dietary lipids and carbohydrates in rats. J. Nutr. 121:959-965.