Effect of topically applied isopropyl unoprostone on microcirculation in the human ocular fundus evaluated with a laser speckle microcirculation analyser

Journal of Japanese Ophthalmological Society

Volumn 101, Issue 7, 1997, Pages 605-610

  Kojima, Shota ^a   Sugiyama, Tetsuya ^a   Azuma, Ikuo ^a   Konishi, Naoki ^b   Fujii, Hitoshi ^b  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Capillary blood flow of optic nerve head; Choroid retinal circulation; Human eye; Isopropyl unoprostone; Laser speckle method

Indexed keywords

EYE DROPS; UNOPROSTONE ISOPROPYL ESTER;

ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CHOROID VASCULARIZATION; CONTROLLED STUDY; EYE FUNDUS; HUMAN; HUMAN EXPERIMENT; INTRAOCULAR PRESSURE; MICROCIRCULATION; NORMAL HUMAN; OPTIC NERVE; PULSE RATE; RETINA BLOOD FLOW; TOPICAL DRUG ADMINISTRATION;

ADULT; BLOOD PRESSURE; CHOROID; DINOPROST; FUNDUS OCULI; HUMANS; INTRAOCULAR PRESSURE; LASER-DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; MIDDLE AGED; OPHTHALMIC SOLUTIONS; OPTIC DISK; PULSE; RETINAL VESSELS;

EID: 0030747438     PISSN: 00290203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Levene ZR: Low tension glaucoma: A critical review and new material. Surv Ophthalmol 24: 621-664, 1980.
2. Drance MS: Disc hemorrhages in the glaucomas. Surv Ophthalmol 33: 331-337, 1989.
3. Haefliger OI, Meyer P, Flammer J, Lüscher T: The vascular endothelium as a regulator of ocular circulation: A new concept in opththalmology? Surv Ophthalmol 39: 123-132, 1994.
4. Flammer J: The vascular concept of glaucoma. Surv Ophthalmol 38: [Suppl. May]: S 3-S 6, 1994.
5. Schwartz B: Circulatory defects of the optic disc and retina in ocular hypertension and high pressure open-angle glaucoma. Surv Ophthalmol 38: [Suppl, May] : S 23-S 34, 1994.
6. Sergott CR, Aburn SN, Trible RJ, Lieb EW, Flahrty MP: Color Doppler imaging: Methodology and preliminary results in glaucoma. Surv Ophthalmol 38: [Suppl, May] : S 65-S 71, 1994.
7. Sugiyama T, Azuma I: Effect of UF-021 on optic nerve head circulation in rabbits. Jpn J Ophthalmol 39: 124-139, 1995.
8. Tamaki Y, Araie M, Kawamoto E, Eguchi S, Fujii H: Non-contact, two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon. Exp Eye Res 60: 373-384, 1995.
9. Sugiyama T, Utsumi T, Azuma I, Fujii H: Measurement of optic nerve head circulation: comparison of laser speckle and hydrogen clearance methods. Jpn J Ophthalmol 40: 339-343, 1996.
10. Stjernschantz J, Nilsson SFE, Astin M: Vasodynamic and angiogenic effects of eicosanoids in the eye. Porg Clin Biol Res 312 : 155 -170, 1989.
11. 2α-induced ocular hyperemia. Exp Eye Res 59: 401-408, 1994.
12. Kitamura Y, Okamura T, Kani K, Toda N: Nitric oxide mediated retinal arteriolar and arterial dilatation induced by substance P. Invest Ophthalmol Vis Sci 34: 2859-2865, 1993.
13. Mann MR, Riva EC, Stjone AR, Barnes EG, Cranstoun DS: Nitric oxide and choroidal blood flow regulation. Invest Ophthalmol Vis Sci 36: 925-930, 1995.
14. Sakurai M, Araie M, Oshika T, Mori M, Masuda K, Ueno R, Takase M: Effects of topical application of UF-021, a novel prostaglandin derivative, on aqueous humor dynamics in normal human eyes. Jpn J Ophthalmol 35: 156-165, 1991