Genomic structure of the bovine mb-1 gene encoding the Ig-α subunit of the B cell antigen receptor complex

Veterinary Immunology and Immunopathology

Volumn 56, Issue 3-4, 1997, Pages 247-257

  Youn, Hwa Young ^a   Cho, Kyu Woan ^b   Nishimura, Yoshiaki ^b   Goitsuka, Ryo ^c   Watari, Toshihiro ^b   Tsujimoto, Hajime ^b   Hasegawa, Atsuhiko ^b  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

B lymphocyte; Bovine; Genomic mb 1 gene

Indexed keywords

IMMUNOGLOBULIN A; LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CATTLE; DISULFIDE BOND; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; IMMUNOGLOBULIN PRODUCTION; MOLECULAR CLONING; NONHUMAN; PROTEIN CONFORMATION; SEQUENCE ANALYSIS; TATA BOX;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD79; BASE SEQUENCE; BINDING SITES; CATTLE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENOME; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; RECEPTORS, ANTIGEN, B-CELL; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

ANIMALIA; BOS TAURUS; BOVINAE; BOVINE LEUKEMIA VIRUS; MURINAE;

EID: 0030746362     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(96)05756-X     Document Type: Article

References (38)

1. Bachmann, M.F., Rohrer, U.H., Kundig, T.M., Burki, K., Hengartner, H. and Zinkernagel, R.M., 1993. The influence of antigen organization on B cell responsiveness. Science, 262: 1448-1451.
2. Breathnach, R. and Chambon, P., 1981. Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem., 50: 349-383.
3. Burny, A., Cleuter, Y., Kettmann, R., Mammerickx, M., Marbaix, G., Portetelle, D., Van den Broeke, A., Willems, L. and Thomas, M., 1987. Bovine leukaemia: Facts and hypotheses derived from the study of an infectious cancer. Vet. Microbiol., 17: 197-218.
4. Cambier, J.C. and Campbell, K.C., 1992. Membrane immunoglobulin and its accomplices: New lessons from and old receptor. FASEB, J., 6: 3207-3217.
5. Clark, E.A. and Lane, P.J., 1991. Regulation of human B-cell activation and adhesion. Annu. Rev. Immunol., 9: 97-127.
6. Costa, T.E., Franke, R.R., Sanchez, F.M., Misulovin, Z. and Nusssenzweig, M.C., 1992. Functional reconstitution of an immunoglobulin antigen receptor in T cells. J. Exp. Med., 175: 1669-1676.
7. Derse, D., 1987. Bovine leukemia virus transcription is controlled by a virus-encoded trans-acting factor and by cis-acting response elements. J. Virol., 61: 2462-2471.
8. Dynan, W.S., Saffer, J.D., Lee, W.S. and Rjian, R., 1985. Transcription factor SpI recognizes promoter sequences from the monkey genome that are simian virus 40 promoter. Natl. Acad. Sci. USA, 82: 4915-4919.
9. Eisen, P.V.-D., Georgopoulous, K., Shepley, B.-A., Orkin, S. and Terhost, C., 1986. Exon/intron organization of the genes coding for the δ chains of the human and murine T cell receptor/T3 complex. Proc. Natl. Acad. Sci. USA, 83: 2944-2948.
10. Faisst, S. and Meyer, S., 1992. Compilation of vertebrate-encoded transcription factors. Nucl. Acids Res., 20: 3-26.
11. Feldbaus, A., Mbangkollo, D., Arvin, K.L., Klug, C.A. and Singh, H., 1992. BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1. Mol. Cell. Biol., 12: 1126-1133.
12. Gigueve, V., Isobe, K.-I. and Grosveld, F., 1985. Structure of the murine Thy-1 gene. EMBO J., 4: 437-443.
13. Ha, H., Kubagawa, H. and Burrows, P.D., 1992. Molecular cloning and expression pattern of human gene homologous to the murine mb-1 gene. J. Immunol., 148: 1526-1531.
14. Ha, H., Barnoski, B.L., Sun, L., Emanuel, B.S. and Burrows, P.D., 1994. Structure, chromosomal localization, and methylation pattern of the human mb-1 gene. J. Immunol., 152: 5749-5757.
15. Hagman, J. and Grosschedl, R., 1992. An inhibitor carboxyl-terminal: Domain in Ets-1 ad Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. Proc. Natl. Acad. Sci. USA, 89: 8889-8893.
16. Hagman, J., Belanger, C., Travis, A., Turck, C.W. and Grosschedl, R., 1993. Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte specific gene expression. Genes Dev., 7: 760-773.
17. Hermanson, G.G., Eisenberg, D., Kincade, P.W. and Wall, R., 1988. B29: A member of the immunoglobulin gene superfamily exclusively expressed on B lineage cells. Proc. Natl. Acad. Sci. USA, 85: 6890-6893.
18. Hermanson, G.G., Briskin, M., Sigman, D. and Wall, R., 1989. Immunoglobulin enhancer and promoter motifs 5' of the B29 B-cell-specific gene. Proc. Natl. Acad. Sci. USA, 86: 7341-7345.
19. Javahery, R., Khachi, A., Lo, K., Zenzie-Gregory, B. and Smale, S.T., 1994. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol., 14: 116-127.
20. Kashiwamura, S.-I., Koyama, T., Matsuo, T., Steinmetz, M., Kimoto, M. and Sakaguchi, N., 1990. Structure of the murine mb-1 gene encoding a putative sIgM-associated molecule. J. Immunol., 145: 337-343.
21. tax activates heterologous promoters with a common sequence known as a cAMP-responsive element of the binding site of a cellular transcription factor ATF. EMBO J., 8: 497-503.
22. pre-B in the λ5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. EMBO J., 6: 2267-2272.
23. Lenardo, M.J. and Baltimore, D., 1984. NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control. Cell, 58: 227-229.
24. Lenardo, M.J., Pierce, J.W. and Baltimore, D., 1987. Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science, 236: 1573-1577.
25. Lin, H. and Grosschedl, R., 1995. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature, 376: 263-267.
26. Matsuuchi, L., Gold, M.R., Travis, A., Grosschedl, R., DeFranco, A. and Kelly, R.B., 1992. The membrane IgM-associated proteins MB-1 and Ig-b are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlimphoid cell line. Proc. Natl. Acad. Sci. USA, 89: 3404-3408.
27. Müller, B., Cooper, L. and Terhorst, C., 1992. Cloning and sequencing of the cDNA encoding the humane homologue of the murine immunoglobulin-associated protein B29. Eur. J. Immunol., 22: 1621-1625.
28. Nakamura, T., Kubagawa, H. and Cooper, M.D., 1992. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc. Natl. Acad. Sci. USA, 89: 8522-8526.
29. Pleiman, C.M., D'Ambrosio, D. and Cambier, J.C., 1994. The B-cell antigen receptor complex: Structure and signal transduction. Immunol. Today, 15: 393-399.
30. Reth, M., 1992. Antigen receptors on B lymphocytes. Annu. Rev. Immunol., 10: 97-121.
31. Schmidt, M.C., Zhou, Q. and Berk, A.J., 1989. Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor. Mol. Cell. Biol., 9: 3299-3307.
32. Smale, S.T. and Baltimore, D., 1989. The 'initiator' as a transcription control element. Cell, 57: 103-113.
33. Travis, A., Hagman, J. and Grosschedl, R., 1991. Heterogeneously initiated transcription from the pre-B- and B-cell-specific promoter: Analysis of the requirement for upstream factor-binding sites and initiation site sequence. Mol. Cell. Biol., 11: 5756-5766.
34. Wasylyk, B., Wasylyk, C., Flores, P., Begue, A., Leprince, D. and Stehelin, D., 1990. The c-ets. Proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation. Nature, 346: 191-193.
35. Willems, L., Gegonne, A., Chen, G., Burny, A., Kettmann, R. and Ghysdael, J., 1987. The bovine leukemia virus p34 is a transactivator protein. EMBO J., 6: 3385-3389.
36. Wilson, G.L., Najfeld, V., Kozlow, E., Menning, J., War, D. and Kehrl, J.H., 1993. Genomic structure and chromosomal mapping of the human CD22 gene. J. Immunol., 150: 5013-5024.
37. Youn, H.-Y., Goitsuka, R., Okuda, M., Watari, T., Tsujimoto, H. and Hsegawa, A., 1994. Two forms of the mb-1 gene transcript in cattle. J. Immunol., 153: 5127-5132.
38. Youn, H.-Y., Goitsuka, R., Kato, H., Watari, T., Tsujimoto, H. and Hsegawa, A., 1996. Molecular cloning of bovine mb-1 cDNA. Vet. Immunol. Immunopathol., 52: 191-200.