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Sundin DP, Meyer C, Dahl R, Geerdes A, Sandoval R, Molitoris BA: Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment. Am J Physiol (In press). The authors showed that continued administration of gentamicin induced a selective decrease in apical gentamicin endocytosis that was independent of changes in megalin levels or distribution and surface membrane binding.
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