Development of in vitro-in vivo correlations using various artificial neural network configurations

Advances in Experimental Medicine and Biology

Volumn 423, Issue , 1997, Pages 225-239

  Dowell, James A ^a   Hussain, Ajaz S ^b   Stark, Paul ^c   Devane, John ^c   Young, David ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c ELAN PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ARTIFICIAL NEURAL NETWORK; CORRELATION FUNCTION; IN VITRO STUDY; IN VIVO STUDY; PHARMACEUTICS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0030745607     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4684-6036-0_22     Document Type: Article

References (18)

1. T. J. Sullivan, E. Sakmar, and J. G. Wagner. Comparative bioavailability: a new type of m vitro-in vivo correlation exemplified by prednisone. J. Pharmacokin. Biopharm. 4:173-181 (1976).
2. C. Graffner, M. Nicklasson, and J.-E. Lindgren. Correlations between in vitro dissolution rate and bioavailability of alaproclate tablets. J. Pharmacokin. Biopharm. 12:367-380 (1984).
3. C. Caramella, F. Ferrari, M. C. Bonferoni, M. E. Sangalli, M. De Bernardi Di Valserra, F. Feletti, and M. R. Galmozzi. In vitro / in vivo correlation of prolonged release dosage forms containing diltiazem HCl. Biopharm. Drug Disp. 14:143-160, (1993).
4. R. W. Wood, L. Martis, A. W. Gillum, T. J. Roseman, L. Lin, and P. Bernardo. In vitro dissolution and in vivo bioavailability of commercial levothyroxine sodium tablets in the hypothyroid dog model. J. Pharm. Sci. 79:124-127 (1990).
5. W. H. Barr, E. M. Zola, E. L. Candler, S.-M. Hwang, A. V. Tendolkar, R. Shamburek, B. Parker, and M. D. Hilty. Differential absorption of amoxicillin from the human small and large intestine. Clin. Pharmacol. Ther. 56:279-285 (1994).
6. G. Levy and L. E. Hollister. Inter- and intra subject variations in drug absorption kinetics. J. Pharm. Sci. 53:1446-1452 (1964).
7. J. A. Anderson. An introduction to neural networks, MIT Press, Cambridge, 1995.
8. S.I. Gallant. Neural Network Learning and Expert Systems, MIT press, Cambridge, 1993.
9. M. T. Hagan, H. B. Demuth, and M. Beale. Neural Network Design, PWS Publishing Company, Boston, 1996.
10. R. Erb. Introduction to backpropagation neural network computation. Pharm. Res. 10:165-170 (1993).
11. R. Erb. The backpropagation neural network - A bayesian classifier. Introduction and applicability to pharmacokinetics. Clin. Pharmacokinet. 29:69-79 (1995).
12. A. S. Hussain, R. D. Johnson, N. N. Vachharajani, and W. A. Ritschel. Feasibility of developing a neural network for prediction of human pharmacokinetic parameters from animal data. Pharm. Res. 10:466-469 (1993).
13. S. Haykin. Neural networks: a comprehensive foundation, Macmillan, New York, 1994.
14. NeuroShell® 2 Manual Third Edition, Ward Systems Group, Inc. Executive Park West, 5 Hillcrest Drive, Frederick, MD 21702. (1995).
15. J. L. Elman. Finding structure intime. Cognitive Science. 14:179-211 (1990).
16. P. Veng-Pedersen and N. B. Modi. Application of neural networks to pharmacodynamics. J. Pharm. Sci. 82:918-926 (1991).
17. J. De Villiers and E. Barnard. Backpropagation neural nets with one and two hidden layers. IEEE Trans. Neural Networks. 4:136-141 (1992).
18. D. F. Specht. A general regression neural network. IEEE Transactions on Neural Networks. 2: 568-576 (1991).