Expression of human group II phospholipase A2 in transgenic mice

Journal of Histochemistry and Cytochemistry

Volumn 45, Issue 8, 1997, Pages 1109-1119

  Nevalainen, Timo J ^a   Laine, V Jukka O ^a   Grass, David S ^b  

^a UNIVERSITY OF TURKU   (Finland)

^b Chrysalis DNX Transgenic Sciences   (United States)

Author keywords

Acute phase response; Immunohistochemistry; In situ hybridization; Inflammation; mRNA; Phospholipase A2; Riboprobes; Transgenic mice

Indexed keywords

MESSENGER RNA; PHOSPHOLIPASE A2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS MUSCULUS; ORYCTOLAGUS CUNICULUS;

EID: 0030745441     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549704500808     Document Type: Article

References (40)

1. Andersen S, Sjursen W, Laegreid A, Austgulen R, Johansen B (1994) Immunohistologic detection of non-pancreatic phospholipase A2 (type II) in human placenta and its involvement in normal parturition at term. Prostaglandins Leukotrienes Essent Fatty Acids 51:19-26
2. 2+-dependent phospholipase A2. J Biol Chem 269:2365-2368
3. Chock SP, Schmauder-Chock EA, Cordella-Miele E, Miele L, Mukherjee AB (1994) The localization of phospholipase A2 in the secretory granule. Biochem J 300:619-622
4. 2+-dependent translocation domain with homology to PKC and GAP. Cell 65:1043-1051
5. Crowl RM, Stoller TJ, Conroy RR, Stoner CR (1991) Induction of phospholipase A2 gene expression in human hepatoma cells by mediators of the acute phase response. J Biol Chem 266: 2647-2651
6. Dennis EA (1994) Diversity of group types regulation and function of phospholipase A2. J Biol Chem 269:13057-13060
7. Di Marco S, Märki F, Hofstetter H, Schmit A, van Oostrum J, Grütter MG (1992) Purification, analysis, and enzymatic activity of recombinant human synovial fluid phospholipase A2 and N-terminal variant. J Biochem 112:350-354
8. Ellies EG, Gupta AK, Aubin JE (1992) Differential regulation of phospholipase A2 by cytokines inhibiting bone formation and mineralization. Biochem Biophys Res Commun 188:1047-1053
9. Grass DS, Falkmer RH, Chiang M-Y, Wallace RE, Nevalainen TJ, Bennett CF, Swanson ME (1996) Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate. J Clin Invest 97:2233-2241
10. Harwig SS, Tan L, Qu XD, Cho Y, Eisenhauer PB, Lehrer RI (1995) Bactericidal properties of murine intestinal phospholipase A2. J Clin Invest 95:603-610
11. Hsu SM, Raine E, Fanger H (1981) The use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577-580
12. Kennedy BP, Payette P, Mudgett J, Vadas P, Pruzanski W, Kwan M, Tang C, Rancourt DE, Cromlish A (1995) A natural disruption of the secretory group II phospholipase A2 gene in inbred mouse strains. J Biol Chem 270:22378-22385
13. Kiyohara H, Egami H, Shibata Y, Murata K, Ohshima S, Ogawa M (1992) Light microscopic immunohistochemical analysis of the distribution of group II phospholipase A2 in human digestive organs. J Histochem Cytochem 40:1659-1664
14. Kortekangas P, Aro HT, Nevalainen TJ (1994) Group II phospholipase A2 in synovial fluid and serum in acute arthritis. Scand J Rheumatol 21:283-288
15. Kramer RM, Hession C, Johansen B, Hayes G, McGray P, Chow EP, Tizard R, Pepinsky RB (1989) Structure and properties of a human non-pancreatic phospholipase A2. J Biol Chem 264: 5768-5775
16. Martikainen P, Nyman K, Nevalainen TJ (1993) Toxic effects of human pancreatic and snake and bee venom phospholipases A2 on MCF-7 cells in culture. Toxicon 31:835-843
17. Morgan DW, Anderson GM, Meyers KP (1993) Recombinant human type II phospholipase A2 lacks edema producing activity in rat. Eur J Pharmacol 235:45-50
18. 2 synthesis in human imbilical vein endothelial cells: possible participation of cytosolic and extracellular type II phospholipases A2. J Biol Chem 268:839-844
19. Murakami M, Kudo I, Suwa Y, Inoue K (1992) Release of 14-kDa group-II phospholipase A2 from activated mast cells and its possible involvement in the regulation of the degranulation process. Eur J Biochem 209:257-265
20. Nakano T, Arita H (1990) Enhanced expression of group II phospholipase A2 gene in the tissues of endotoxin shock rats and its suppression by glucocorticoids. FEBS Lett 273:23-26
21. Nakano T, Ohara O, Teraoka H, Arita H (1990) Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells. FEBS Lett 261: 171-174
22. Nevalainen TJ (1993) Serum phospholipases A2 in inflammatory diseases. Clin Chem 39:2453-2459
23. Nevalainen TJ, Aho HJ, Peuravuori H (1994) Secretion of group 2 phospholipase A2 by lacrimal gland. Invest Ophthalmol Vis Sci 32:417-421
24. Nevalainen TJ, Grönroos JM, Kallajoki M (1995) Expression of group II phospholipase A2 in human gastrointestinal tract. Lab Invest 72:201-208
25. Nevalainen TJ, Haapanen TJ (1993) Distribution of pancreatic (group I) and synovial-type (group II) phospholipases A2 in human tissues. Inflammation 17:453-464
26. Nevalainen TJ, Kallajoki M, Pesonen E, Andesson S, Kärkkäinen P, Höckerstedt K (1996) Origin of circulating group II phospholipase A2 in hepatocytes in a patient with epitheloid hemangioendothelioma of the liver. Lab Invest 74:585-591
27. Nevalainen TJ, Märki F, Kortesuo PT, Grütter M, Di Marco S, Schmitz A (1993) Synovial type (group II) phospholipase A2 in cartilage. J Rheumatol 20:325-330
28. Nguyen HT, Rice GE, Farrugia W, Wong M, Brennecke SP (1994) Bacterial endotoxin increases type II phospholipase A2 immunoreactive content and phospholipase A2 enzymatic activity in human decidua. Biol Reprod 50:526-534
29. Nomura K, Fujita H, Arita H (1994) Gene expression of pancreatic-type phospholipase A2 in rat ovaries: stimulatory action on progesterone release. J Biol Chem 135:603-609
30. Oka S, Arita H (1991) Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. J Biol Chem 266:9956-9960
31. Okazaki T, Strauss JFI, Flickinger GL (1977) Lysosomal phospholipase A activities of rat ovarian tissue. Biochim Biophys Acta 487:343-353
32. Rosenthal MD, Gordon MN, Buescher ES, Slusser JH, Harris LK, Franson RC (1995) Human neutrophils store type II 14-kDa phospholipase A2 in granules and secrete active enzyme in response to soluble stimuli. Biochem Biophys Res Commun 208: 650-656
33. Seilhamer JJ, Pruzanski W, Vadas P, Plant S, Miller JA, Kloss J, Johnson LK (1989) Cloning and recombinant expression of phospholipase A2 present in rheumatoid arthritic synovial fluid. J Biol Chem 264:5335-5338
34. Seilhamer JJ, Randall TL, Yamanaka M, Johnson LK (1986) Pancreatic phospholipase A2: isolation of the human gene and cDNAs from porcine pancreas and human lung. DNA 5:519-527
35. Vadas P, Browning J, Edelson J, Pruzanski W (1993) Extracellular phospholipase A2 expression and inflammation: the relationship with associated disease states. J Lipid Mediators 8:1-30
36. van den Bosch H (1980) Intracellular phospholipases A. Biochim Biophys Acta 604:191-246
37. Veldhuis JD, Demers LM (1989) Mechanism(s) by which activation of protein kinase C is coupled to prostacyclin synthesis in granulosa cells. Endocrinology 63:219-226
38. Weinrauch Y, Elsbach P, Madsen LM, Foreman A, Weiss J (1996) The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2. J Clin Invest 97:250-257
39. Wright GW, Ooi CE, Weiss J, Elsbach P (1990) Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate. J Biol Chem 265:6675-6681
40. Ying Z, Tojo H, Komatsubara T, Nakagawa M, Inada M, Kawata S, Matsuzawa Y, Okamoto M (1994) Enhanced expression of group II phospholipase A2 in human hepatocellular carcinoma. Biochim Biophys Acta 1226:201-205