Lens-preferred activity of chicken δ1- and δ2-crystallin enhancers in transgenic mice and evidence for retinoic acid-responsive regulation of the δ1-crystallin gene

Developmental Genetics

Volumn 20, Issue 3, 1997, Pages 258-266

  Li, Xuan ^a,c   Cvekl, Aleš ^a   Bassnett, Steven ^b   Piatigorsky, Joram ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Origene Technologies   (United States)

Author keywords

Crystallin; Enhancers; Gene expression; Lens; Retinoic acid; Transgenic mice

Indexed keywords

CRYSTALLIN; RETINOIC ACID;

ANIMAL TISSUE; ARTICLE; CHICKEN; DNA FLANKING REGION; ENHANCER REGION; EXON; EYE DEVELOPMENT; GENE EXPRESSION REGULATION; LENS EPITHELIUM; LIGHT REFRACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; TANDEM REPEAT; TRANSGENIC MOUSE;

ANIMALS; CHICKENS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CRYSTALLINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; LENS, CRYSTALLINE; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); RECEPTORS, RETINOIC ACID; TRETINOIN;

ANIMALIA; FELIS CATUS; GALLUS GALLUS; MUS MUSCULUS;

EID: 0030745384     PISSN: 0192253X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6408(1997)20:3<258::AID-DVG8>3.0.CO;2-6     Document Type: Article

References (44)

1. Barbosa P, Wistow GJ, Cialkowski M, Piatigorsky J (1991): Expression of duck lens delta-crystallin cDNAs in yeast and bacteria hosts: Delta 2-crystallin is an active argininosuccinate lyase. J Biol Chem 266:22319-22322.
2. Bassnett S (1992): Mitochondrial dynamics in differentiating fiber cells of the mammalian lens. Curr Eye Res 11:1227-1232.
3. Bassnett S, Beebe DC (1992): Coincident loss of mitochondria and nuclei during lens fiber cell differentiation. Dev Dynamics 194:85-93.
4. Bloemendal H (1982): Lens proteins. CRC Crit Rev Biochem 12:1-38.
5. Cvekl A, Piatigorsky J (1996): Lens development and crystallin gene expression: Many roles for Pax-6. BioEssays 18:621-630.
6. Cvekl A, Sax CM, Li X, McDermott JB, Piatigorsky J (1995): Pax-6 and lens-specific transcription of the chicken 81-crystallin gene. Proc Natl Acad Sci USA 92:4681-4685.
7. Duncan MK, Roth HJ, Thompson M, Kantorow M, Piatigorsky J (1995): Chicken βB1-crystallin: Gene sequence and evidence for functional conservation of promoter activity between chicken and mouse. Biochim Biophys Acta 1261:68-76.
8. Funahashi J, Kamachi Y, Goto K, Kondoh H (1991): Identification of nuclear factor δEF1 and its binding site essential for lens-specific activity of the δ1-crystallin enhancer. Nucleic Acids Res 19:3543-3547.
9. Funahashi J, Sekido R, Murai K, Kamachi Y, Kondoh H (1993): δ-crystallin enhancer binding protein δEF1 is a zinc finger homeodomain protein implicated in postgastrulation embryogenesis. Development 119:444-446.
10. Giguere V (1994): Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocrinol Rev 15:61-79.
11. Goto K, Hayashi S, Shirayoshi Y, Takeichi M, Kondoh H (1988): Exogenous delta-crystallin gene expression as probe for differentiation of teratocarcinoma stem cells. Cell Differ 24:139-147.
12. Goto K, Okada TS, Kondoh H (1990): Functional cooperation of lens-specific and nonspecific elements in the δ1-crystallin enhancer. Mol Cell Biol 10:958-964.
13. Harding JJ, Delley KJ (1976): Structural proteins of the mammalian lens: A review with emphasis on changes in development, aging and cataract. Exp Eye Res 22:1-73.
14. Hayashi S, Goto K, Okada TS, Kondoh H (1987): Lens-specific enhancer in the third intron regulates expression of the chicken δ1-crystallin gene. Genes Dev 1:818-828.
15. Head MW, Triplett EL, Clayton RM (1991): Independent regulation of two coexpressed δ-crystallin genes in chick lens and nonlens tissues. Exp Cell Res 193:370-374.
16. Kamachi Y, Sockanathan S, Liu Q, Breitman M, Lovell-Badge R, Kondoh H (1995): Involvement of SOX proteins in lens-specific activation of crystallin genes. EMBO J 14:3510-3519.
17. Kamachi Y, Kondoh H (1993): Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1-crystallin enhancer. Mol Cell Biol 13:5206-5215.
18. Kondoh H, Araki I, Yasuda K, Matsubasa T, Mori M (1991): Expression of the chicken 'Delta2-crystallin' gene in mouse cells: Evidence for encoding of argininosuccinate lyase. Gene 99:267-271.
19. Kondoh H, Katoh K, Takahashi Y, Fujisawa H, Yokoyama M, Kimura S, Katsuki M, Saito M, Nomura T, Hiramoto Y, Okada TS (1987): Specific expression of the chicken δ-crystallin gene in the lens and the pyramidal neurons of the piriform cortex in transgenic mice. Dev Biol 120:177-185.
20. Land MF (1988): The optics of animal eyes. Contemp Phys 29:435-455.
21. Li X, Beebe DC (1993): Transcriptional control of δ-crystallin gene expression in the chicken embryo lens: Demonstration by a new method for measuring mRNA metabolism. Mol Cell Biol 13:3282-3290.
22. Li X, Wistow GJ, Piatigorsky J (1995): Linkage and expression of the argininosuccinate lyase/δ-crystallin genes of the duck: Insertion of a CR1 element in the intergenic spacer. Biochim Biohys Acta 1261:25-34.
23. Li X, Zelenka PS, Piatigorsky J (1993): Differential expression of the two δ-crystallin genes in lens and non-lens tissues: Shift favoring δ2 expression from embryonic to adult chickens. Dev Dynamics 196:114-123.
24. Minucci S., Zand DJ, Dey A, Marks MS, Nagata T, Grippo J, Ozato K (1994): Dominant negative retinoid X receptor β inhibits retinoic acid responsive gene regulation in embryonal carcinoma cells. Mol Cell Biol 14, 360-372.
25. Neumann JR, Morency CA, Russian KO (1987): A novel rapid assay for chloramphenicol acetyltransferase gene expression. BioTechniques 5:444-447.
26. Neilsen DA, Chou J, MacKrell AJ, Casadaban MJ, Steiner DF (1983): Expression a prepronsulin-beta-galactosidase gene fusion in mammalian cells. Proc Natl Acad Sci USA 80:5198-5202.
27. Nickerson JM, Wawrousek EF, Hawkins JW, Wakil AS, Wistow GJ, Thomas G, Norman BL, Piatigorsky J (1985): The complete sequence of the chicken 81 crystallin gene and its 5′ flanking region. J Biol Chem 260:9100-9105.
28. Nickerson JM, Wawrousek EF, Borras T, Hawkins JW, Norman B, Filpula DR, Nagle JW, Ally AH, Piatigorsky J (1986): Sequence of the chicken δ2-crystallin gene and its intergenic spacer: Extreme homology with the δ1-crystallin gene. J Biol Chem 261:552-557.
29. Parker DS, Wawrousek EF, Piatigorsky J (1988): Expression of the δ-crystallin genes in the embryonic chicken lens. Dev Biol 126:375-381.
30. Patek CE, Clayton RM (1990): Age-related changes in the response of chick lens cells during long term culture to insulin, cyclic AMP, retinoic acid and a bovine retinal extract. Exp Eye Res 50:345-354.
31. Piatigorsky J (1984): Delta-crystallins and their nucleic acids. Mol Cell Biochem 59:33-56.
32. Piatigorsky J, Wistow G (1989): Enzyme/crystallins: Gene sharing as an evolutionary strategy. Cell 57:197-199.
33. Sax CM, Farrell FX, Zehner ZE, Piatigorsky J (1990): Regulation of vimentin gene expression in the ocular lens. Dev Biol 139:56-64.
34. Sax CM, Ilagan JG, Piatigorsky J (1993): Functional redundancy of the DE-1 and αA-CRYBP1 regulatory sites of the mouse αA-crystallin promoter. Nucleic Acids Res 21:2633-3640.
35. Sekido R, Murai K, Funahashi J, Kamachi Y, Fujisawa-Sehara A, Habeshima Y, Kondoh H (1994): The δ-crystallin enhancer-binding protein δEF1 is a repressor of E2-box-mediated gene activation. Mol Cell Biol 14:5692-5700.
36. Taketo M, Schroeder AC, Mobraaten LE, Gunning KB, Hanten G, Fox RR, Roderick TH, Stewart CL, Lilly F, Hansen CT, Overbeek PA (1991): FVB/N: An inbred mouse strain preferable for transgenic analyses. Proc Natl Acad Sci USA 88:22065-2069.
37. Thomas G, Zelenka P, Cuthberson RA, Norman BL, Piatigorsky J (1990): Differential expression of the two δ-crystallin/argininosucinate lyase genes in lens, heart, and brain of chicken embryos. New Biol 2:903-914.
38. Tini M, Otulakowski G, Breitman M, Tsui LC, Giguere V (1993): An everted repeat mediates retinoic acid induction of the γF-crystallin gene: evidence of a direct role for retinoids in lens development. Genes Dev 7:295-307.
39. Tini M, Fraser RA, Giguere V (1995): Functional interactions between retinoic acid receptor-related orphan nuclear receptor (RORα) and the retinoic acid receptors in the regulation of the γF-crystallin promoter. J Biol Chem 270:20156-20161.
40. Tini M, Tsui L-C, Giguére V (1994): Heterodimeric interaction of the retinoic acid and thyroid hormone receptors in transcriptional regulation on the γF-crystallin everted retinoic acid response element. Mol Endocrinol 8:1494-1506.
41. Wawrousek EF, Chepelinsky AB, McDermott JB, Piatigorsky J (1990): Regulation of the murine αA-crystallin promoter in transgenic mice. Dev Biol 137:68-76.
42. Wawrousek EF, Nickerson JM, Piatigorsky J (1986): Two δ-crystallin polypeptides are derived from a cloned δ1-crystallin cDNA. FEBS Lett 205:235-240.
43. Wistow G, Piatigorsky J (1988): Lens crystals: The evolution and expression of proteins for a highly specialized tissue. Ann Rev Biochem 57:479-504.
44. Wistow G, Piatigorsky J (1990): Gene conversion and splice-site slippage in the argininosuccinate lyases/δ-crystallins of the duck lens: members of an enzyme superfamily. Gene 96:263-270.