Evaluation of the acute behavioral effects and abuse potential of a C8-C9 isoparaffin solvent

Drug and Alcohol Dependence

Volumn 46, Issue 3, 1997, Pages 125-135

  Balster, Robert L ^b   Bowen, Scott E ^b   Evans, Eric B ^a,b   Tokarz, Mary E ^b  

^a NATIONAL STARCH AND CHEMICAL COMPANY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1,1,1 trichloroethane; Drug discrimination; Functional observational battery; Inhalant abuse; Isoparaffins; Mice; Operant behavior; Solvents

Indexed keywords

1,1,1 TRICHLOROETHANE; ALCOHOL; CENTRAL DEPRESSANT AGENT; HYDROCARBON; PARAFFIN; SOLVENT; VOLATILE AGENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABUSE; DRUG DEPENDENCE; DRUG DISCRIMINATION; FEASIBILITY STUDY; INSTRUMENTAL CONDITIONING; MALE; MOTOR COORDINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AROUSAL; BEHAVIOR, ANIMAL; BRAIN; CONDITIONING, OPERANT; DISCRIMINATION LEARNING; ETHANOL; MALE; MICE; MICE, INBRED STRAINS; MOTIVATION; PARAFFIN; SOLVENTS; SUBSTANCE-RELATED DISORDERS; TRICHLOROETHANES;

ANIMALIA;

EID: 0030745372     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(97)00055-0     Document Type: Article

References (23)

1. Balster, R.L., 1987. Abuse potential evaluation of inhalants. Drug Alcohol Depend. 49, 7-15.
2. Balster, R.L., Moser, V.C., 1987. Pentobarbital discrimination in the mouse. Drug Alcohol Depend. 7, 233-242.
3. Balster, R.L., Moser, V.C., Woolverton, W.L., 1982. Concurrent measurement of solvent vapor concentrations and effects on operant behavior using a dynamic exposure system. J. Pharmacol. Methods 8, 299-309.
4. Bowen, S.E., Balster, R.L., 1997. Desflurane, enflurane, isoflurane, and ether produce ethanol-like discriminative stimulus effects in mice. Pharmacol. Biochem. Behav., 57, 191-198.
5. Bowen, S.E., Wiley, J.L., Evans, E.B., Tokarz, M.E., Balster, R.L., 1996. Functional observational battery comparing effects ethanol, 1,1,1-trichloroethane, ether, and flurothyl. Neurotoxicol. Teratol. 18, 1-9.
6. Creason, J.P., 1989. Data evaluation and statistical analysis of functional observational battery data using a linear models approach. J. Am. Coll. Toxicol. 8, 157-169.
7. Dohrn, C.S., Lichtor, J.L., Finn, R.S., Uitvlugt, A., Coalson, D.W., Rupani, G., de Wit, H., Zacny, J.P., 1992. Subjective and psychomotor effects of nitrous oxide in healthy volunteers. Behav. Pharmacol. 3, 19-30.
8. Evans, E.B., Balster, R.L., 1991. CNS depressant effects of volatile organic solvents. Neurosci. Biobehav. Rev. 15, 233-241.
9. Evans, E.B., Balster, R.L., 1993. Inhaled 1,1,1-trichloroethane produced physical dependence in mice: effects of drugs and vapors on withdrawal. J. Pharmacol. Exp. Ther. 264, 726-733.
10. Goldstein, D.B., 1972. An animal model for testing effects of drugs on alcohol reactions. J. Pharmacol. Exp. Ther. 183, 14-22.
11. Moser, V.C., Balster, R.L., 1981. The effects of acute and repeated toluene exposure on operant behavior in mice. Neurobehav. Toxicol. Teratol. 3, 471-475.
12. Moser, V.C., Balster, R.L., 1985. Effects of toluene, halothane and ethanol vapor on fixed-ratio performance in mice. Pharmacol. Biochem. Behav. 22, 797-802.
13. Moser, V.C., Coggeshall, E.M., Balster, R.L., 1985a. Effects of xylene isomers on operant responding and motor performance in mice. Toxicol. Appl. Pharmacol. 80, 293-298.
14. Moser, V.C., Scimeca, J.A., Balster, R.L., 1985b. Minimal tolerance to the effects of 1,1,1-trichloroethane on fixed-ratio responding in mice. Neurotoxicology 6, 35-42.
15. Rees, D.C., Coggeshall, E., Balster, R.L., 1985. Inhaled toluene produces pentobarbital-like discriminative stimulus effects in mice. Life Sci. 37, 1319-1325.
16. Rees, D.C., Knisely, J.S., Breen, T.J., Balster, R.L., 1987a. Pentobarbital-like discriminative stimulus properties of halothane, 1,1,1-trichloroethane, isoamyl nitrite, flurothyl and oxazepam in mice. J. Pharmacol. Exp. Ther. 241, 507-515.
17. Rees, D.C., Knisely, J.S., Breen, T.J., Balster, R.L., 1987b. Toluene, halothane, 1,1,1-trichloroethane and oxazepam produce ethanol-like discriminative stimulus effects in mice. J. Pharmacol. Exp. Ther. 243, 931-937.
18. Sharp, C. 1992. Introduction to inhalant abuse. In: Sharp, C., Beauvais, F., Spence, R. (Eds.), Inhalant Abuse: A Volatile Research Agenda. National Institute on Drug Abuse Research Monograph, 129. DHHS, Rockville, MD, pp. 13-42.
19. Tegeris, J.S., Balster, R.L., 1994. A comparison of the acute behavioral effects of alkylbenzenes using a functional observational battery in mice. Fundam. Appl. Toxicol. 22, 240-250.
20. Tilson, H.A., Moser, V.C., 1992. Comparison of screening approaches. Neurotoxicology 13, 1-14.
21. Woods, J.H., Katz, J.L., Winger, G., 1987. Abuse liability of benzodiazepines. Pharmacol. Rev. 39, 251-419.
22. Woolverton, W.L., Balster, R.L., 1981. Behavioral and lethal effects of combinations of oral ethanol and inhaled 1,1,1-trichloroethane in mice. Toxicol. Appl. Pharmacol. 59, 1-7.
23. Yanagita, T., 1981. Dependence-producing effects of anxiolytics. In: Hoffmeister, F., Stille, G. (Eds.), Handbook of Experimental Pharmacology, 55. Springer, New York. pp. 396-406.