Anxiolytic-like effects of PNU-101017, a partial agonist at the benzodiazepine receptor

Psychopharmacology

Volumn 131, Issue 3, 1997, Pages 255-263

  Tang, A H ^a   Franklin, S R ^a   Carter, D B ^a   Sethy, V H ^a   Needham, L M ^a   Jacobsen, E J ^a   Von Voigtlander, P F ^a  

^a PFIZER INC   (United States)

Author keywords

Anxiolytic; Benzodiazepine; GABA(A) receptor; Partial agonist

Indexed keywords

3 METHYL 6 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 7 CHLORO 5 [(3,5 DIMETHYLPIPERAZINO)CARBONYL]IMIDAZO[1,5 A]QUINOLINE 3 CARBOXYLIC ACID TERT BUTYL ESTER; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; ALCOHOL; BENZODIAZEPINE RECEPTOR; CHLORDIAZEPOXIDE; CORTICOSTEROID; DIAZEPAM; TERT BUTYL 7 CHLORO 5 [(3,5 DIMETHYLPIPERAZINO)CARBONYL]IMIDAZO[1,5 A]QUINOLINE 3 CARBOXYLATE; TRIAZOLAM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANXIETY NEUROSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DEPENDENCE; DRUG MECHANISM; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SEIZURE; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; AVOIDANCE LEARNING; CELLS, CULTURED; CEREBELLUM; CONFLICT (PSYCHOLOGY); CORTICOSTERONE; CYCLIC GMP; DIAZEPAM; DRINKING BEHAVIOR; ELECTROSHOCK; ETHANOL; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; MUSCLE RELAXATION; PENTYLENETETRAZOLE; QUINOLINES; RADIOIMMUNOASSAY; RADIOLIGAND ASSAY; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SEIZURES; STRESS;

EID: 0030745279     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050291     Document Type: Article

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