Apoptosis induced in the spinal cord and dorsal root ganglion by infection of herpes simplex virus type 2 in the mouse

Neuroscience Letters

Volumn 228, Issue 2, 1997, Pages 99-102

  Ozaki, Noriyuki ^a   Sugiura, Yasuo ^b   Yamamoto, Mitsuaki ^c   Yokoya, Sachihiko ^d   Wanaka, Akio ^d   Nishiyama, Yukihiro ^c  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Res Inst Dis Mechanism Contr   (Japan)

^d Institute of Biomedical Sciences   (Japan)

Author keywords

Cell death; Central nervous system; Dorsal root ganglion; Immunohistochemistry; Lumbar cord; Terminal dUTP nick end labeling method

Indexed keywords

VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN DETECTION; APOPTOSIS; ARTICLE; HERPES SIMPLEX VIRUS 2; IMMUNOHISTOCHEMISTRY; LUMBAR SPINAL CORD; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD INFECTION; SPINAL GANGLION;

ANIMALS; ANTIBODIES, VIRAL; APOPTOSIS; BIOTIN; CELL NUCLEUS; DEOXYURACIL NUCLEOTIDES; DNA FRAGMENTATION; GANGLIA, SPINAL; GENOME, VIRAL; HERPES SIMPLEX; HERPESVIRUS 2, HUMAN; MALE; MICE; MICE, INBRED ICR; SPINAL CORD; STAINING AND LABELING;

EID: 0030745276     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00364-9     Document Type: Article

References (17)

1. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death [in situ] via specific labelling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-502.
2. Geiger K.D., Gurushanthaiah D., Howes E.L., Lewandowski G.A., Reed J.C., Bloom F.E., Sarvetnick N.E. Cytokine-mediated survival from lethal herpes simplex virus infection: role of programmed neuronal death. Proc. Natl. Acad. Sci. USA. 92:1995;3411-3415.
3. Hanon E., Vanderplasschen A., Lyaku J., Keil G., Denis M., Pastoret P.-P. Inactivated bovine herpesvirus 1 induces apoptotic cell death of mitogen-stimulated bovine peripheral blood mononuclear cells. J. Virol. 70:1996;4116-4120.
4. Henderson S., Huen D., Rowe M., Dawson C., Johnson G., Rickinson A. Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Proc. Natl. Acad. Sci. USA. 90:1993;8479-8483.
5. Hinrichsen C.F., Stevens G.S. Epithelial morphology during closure of the secondary palate in the rat. Arch. Oral. Biol. 19:1974;969-980.
6. Leopardi R., Roizman B. The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia. Proc. Natl. Acad. Sci. USA. 93:1996;9583-9587.
7. McCarthy S.A., Symonds H.S., Van Dyke T. Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. Proc. Natl. Acad. Sci. USA. 91:1994;3979-3983.
8. Nishiyama Y., Rapp F. Repair replication of viral and cellular DNA in herpes simplex virus type 2-infected human embryonic and xeroderma pigmentosum cells. Virology. 110:1981;466-475.
9. Nishiyama Y., Kimura H., Daikoku T. Complementary lethal invasion of the central nervous system by nonneuroinvasive herpes simplex virus types 1 and 2. J. Virol. 65:1991;4520-4524.
10. Ozaki N., Sugiura Y., Yamamoto M., Nishiyama Y. Induction of Fos protein expression in spinal cord neurons by herpes simplex virus infections in the mouse. Neurosci. Lett. 216:1996;61-64.
11. Pan H., Griep A.E. Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev. 8:1994;1285-1299.
12. Rao L., Debbas M., Sabbatini P., Hockenbery D., Korsmeyer S., White E. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proc. Natl. Acad. Sci. USA. 89:1992;7742-7746.
13. Ray C.A., Black R.A., Kronheim S.R., Greenstreet T.A., Sleath P.R., Salvesen G.S., Pickup D.J. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 converting enzyme. Cell. 69:1992;597-604.
14. Sadzot-Delvaux C., Thonard P., Schoonbroodt S., Piette J., Rentier B. Varicella-zoster virus induces apoptosis in cell culture. J. Gen. Virol. 76:1995;2875-2879.
15. Shen Y., Shenk T.E. Viruses and apoptosis. Curr. Opin. Genet. Dev. 5:1995;105-111.
16. Wyllie A.H., Kerr J.F.R., Currie A.R. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:1980;251-306.
17. Zhu H., Shen Y., Shenk T. Human cytomegalovirus IE1 and IE2 proteins block apoptosis. J. Virol. 69:1995;7960-7970.