-
1
-
-
0024363311
-
Regulation of sigma-receptors: High- and low-affinity agonist states, GTP shifts, and up-regulation by rimcazole and 1,3-di-(2-tolyl) guanidine
-
Beart, P.M., O'Shea, R.D. and Manallack, D.T., Regulation of sigma-receptors: high- and low-affinity agonist states, GTP shifts, and up-regulation by rimcazole and 1,3-di-(2-tolyl) guanidine, J. Neurochem., 53 (1989) 779-788.
-
(1989)
J. Neurochem.
, vol.53
, pp. 779-788
-
-
Beart, P.M.1
O'Shea, R.D.2
Manallack, D.T.3
-
2
-
-
0028845713
-
(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: Highly selective ligands for the sigma-2 receptor subtype
-
Bertha, C.M., Vilner, B.J., Mattson, M.V., Bowen, W.D., Becketts, K., Xu, H., Rothman, R.B., Flippen Anderson, J.L. and Rice, K.C., (E)-8-Benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma-2 receptor subtype, J. Med. Chem., 38 (1995) 4776-4785.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4776-4785
-
-
Bertha, C.M.1
Vilner, B.J.2
Mattson, M.V.3
Bowen, W.D.4
Becketts, K.5
Xu, H.6
Rothman, R.B.7
Flippen Anderson, J.L.8
Rice, K.C.9
-
3
-
-
0028171147
-
3H]RS-23597-190, a potent 5-hydroxytryptamine antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain
-
3H]RS-23597-190, a potent 5-hydroxytryptamine antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain, J. Pharmacol. Exp. Ther., 271 (1994) 484-493.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 484-493
-
-
Bonhaus, D.W.1
Loury, D.N.2
Jakeman, L.B.3
Hsu, S.A.4
To, Z.P.5
Leung, E.6
Zeitung, K.D.7
Eglen, R.M.8
Wong, E.H.9
-
4
-
-
0029068247
-
CB-64D and CB-184: Ligands with high sigma 2 receptor affinity and subtype selectivity
-
Bowen, W.D., Bertha, C.M., Vilner, B.J. and Rice, K.C., CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity, Eur. J. Pharmacol., 278 (1995) 257-260.
-
(1995)
Eur. J. Pharmacol.
, vol.278
, pp. 257-260
-
-
Bowen, W.D.1
Bertha, C.M.2
Vilner, B.J.3
Rice, K.C.4
-
5
-
-
0025975232
-
Psychomotor activity and cognitive disruption attributable to NMDA, but not sigma, interactions in primates
-
Boyce, S., Rupniak, N.M., Steventon, M.J., Cook, G. and Iversen, S.D., Psychomotor activity and cognitive disruption attributable to NMDA, but not sigma, interactions in primates, Behav. Brain Res., 42 (1991) 115-121.
-
(1991)
Behav. Brain Res.
, vol.42
, pp. 115-121
-
-
Boyce, S.1
Rupniak, N.M.2
Steventon, M.J.3
Cook, G.4
Iversen, S.D.5
-
6
-
-
0025936244
-
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs
-
Brent, P.J., Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs, Psychopharmacology (Berlin), 105 (1991) 421-427.
-
(1991)
Psychopharmacology (Berlin)
, vol.105
, pp. 421-427
-
-
Brent, P.J.1
-
7
-
-
0023820905
-
Activation of the A sub(10) mesolimbic system by the sigma receptor agonist (+)SKF 10,047 can be blocked by rimcazole, a novel putative antipsychotic
-
Ceci, A., Smith, M. and French, E.D., Activation of the A sub(10) mesolimbic system by the sigma receptor agonist (+)SKF 10,047 can be blocked by rimcazole, a novel putative antipsychotic, Eur. J. Pharmacol., 154 (1988) 53-57.
-
(1988)
Eur. J. Pharmacol.
, vol.154
, pp. 53-57
-
-
Ceci, A.1
Smith, M.2
French, E.D.3
-
8
-
-
0024093449
-
Glutamate neurotoxicity and diseases of the nervous system
-
Choi, D.W., Glutamate neurotoxicity and diseases of the nervous system, Neuron, 1 (1988) 623-634.
-
(1988)
Neuron
, vol.1
, pp. 623-634
-
-
Choi, D.W.1
-
9
-
-
0025790046
-
3H]tolyl)guanidine with sigma 2 binding sites in rat heart membrane preparations
-
3H]tolyl)guanidine with sigma 2 binding sites in rat heart membrane preparations, Eur. J. Pharmacol., 209 (1991) 245-248.
-
(1991)
Eur. J. Pharmacol.
, vol.209
, pp. 245-248
-
-
Dumont, M.1
Lemaire, S.2
-
10
-
-
0022455440
-
Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain
-
Ferris, R.M., Tang, F.L., Chang, K. and Russel, A., Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain, Life Sci., 38 (1986) 2329-2337.
-
(1986)
Life Sci.
, vol.38
, pp. 2329-2337
-
-
Ferris, R.M.1
Tang, F.L.2
Chang, K.3
Russel, A.4
-
11
-
-
0022196308
-
Phencyclidine and sigma opiate receptors in brain: Biochemical and autoradiographic differentiation
-
Gundlach, A.L., Largent, B.L. and Snyder, S.H., Phencyclidine and sigma opiate receptors in brain: biochemical and autoradiographic differentiation, Eur. J. Pharmacol., 113 (1985) 465-466.
-
(1985)
Eur. J. Pharmacol.
, vol.113
, pp. 465-466
-
-
Gundlach, A.L.1
Largent, B.L.2
Snyder, S.H.3
-
12
-
-
0028180570
-
Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: Characterization by ligand binding and photoaffmity labeling
-
Hellewell, S.B., Bruce, A., Feinstein, G., Orringer, J., Williams, W. and Bowen, W.D., Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffmity labeling, Eur. J. Pharmacol., 268 (1994) 9-18.
-
(1994)
Eur. J. Pharmacol.
, vol.268
, pp. 9-18
-
-
Hellewell, S.B.1
Bruce, A.2
Feinstein, G.3
Orringer, J.4
Williams, W.5
Bowen, W.D.6
-
14
-
-
0026543952
-
Sigma ligand-induced emesis in the pigeon
-
Hudzik, T.J., Sigma ligand-induced emesis in the pigeon, Pharmacol. Biochem. Behav., 41 (1992) 215-217.
-
(1992)
Pharmacol. Biochem. Behav.
, vol.41
, pp. 215-217
-
-
Hudzik, T.J.1
-
15
-
-
0026001542
-
Binding of sigma-ligands to C57BL/6 mouse brain membranes: Effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes
-
Itzhak, Y., Stein, I., Zhang, S.H., Kassim, C.O. and Cristante, D., Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes, J. Pharmacol. Exp. Ther., 257 (1991) 141-148.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.257
, pp. 141-148
-
-
Itzhak, Y.1
Stein, I.2
Zhang, S.H.3
Kassim, C.O.4
Cristante, D.5
-
16
-
-
0026009873
-
Autoradiographic distribution of sigma receptors in human neocortex, hippocampus, basal ganglia, cerebellum, pineal and pituitary glands
-
Jansen, K.L., Faull, R.L., Dragunow, M. and Leslie, R.A., Autoradiographic distribution of sigma receptors in human neocortex, hippocampus, basal ganglia, cerebellum, pineal and pituitary glands, Brain Res., 559 (1991) 172-177.
-
(1991)
Brain Res.
, vol.559
, pp. 172-177
-
-
Jansen, K.L.1
Faull, R.L.2
Dragunow, M.3
Leslie, R.A.4
-
17
-
-
0025916272
-
Pharmacological characterization of sigma binding sites in guinea pig brain membranes
-
Karbon, E.W. and Enna, S.J., Pharmacological characterization of sigma binding sites in guinea pig brain membranes. Adv. Exp. Med. Biol., 287 (1991) 51-59.
-
(1991)
Adv. Exp. Med. Biol.
, vol.287
, pp. 51-59
-
-
Karbon, E.W.1
Enna, S.J.2
-
18
-
-
0023219059
-
Non-competitive antagonists of excitatory amino acid receptors
-
Kemp, J.A., Foster, A.C. and Wong, E.H.F., Non-competitive antagonists of excitatory amino acid receptors, Trends Neurosci., 10 (1987) 294-298.
-
(1987)
Trends Neurosci.
, vol.10
, pp. 294-298
-
-
Kemp, J.A.1
Foster, A.C.2
Wong, E.H.F.3
-
19
-
-
0023743162
-
Novel antipsychotic drugs share high affinity for the sigma receptor
-
Largent, B.L., Wikstrom, H., Snowman, A.M. and Snyder, S.H., Novel antipsychotic drugs share high affinity for the sigma receptor, Eur. J. Pharmacol., 155 (1988) 345-347.
-
(1988)
Eur. J. Pharmacol.
, vol.155
, pp. 345-347
-
-
Largent, B.L.1
Wikstrom, H.2
Snowman, A.M.3
Snyder, S.H.4
-
20
-
-
0026459402
-
Sigma receptors are associated with cortical limbic areas in the primate brain
-
Mash, D.C. and Zabetian, C.P., Sigma receptors are associated with cortical limbic areas in the primate brain, Synapse, 12 (1992) 195-205.
-
(1992)
Synapse
, vol.12
, pp. 195-205
-
-
Mash, D.C.1
Zabetian, C.P.2
-
21
-
-
0025962486
-
Sigma receptor ligands alter concentrations of corticosterone in plasma in the rat
-
Matheson, G.K., Guthrie, D., Bauer, C., Knowles, A., White, G. and Ruston, C., Sigma receptor ligands alter concentrations of corticosterone in plasma in the rat, Neuropharmacology, 30 (1991) 79-87.
-
(1991)
Neuropharmacology
, vol.30
, pp. 79-87
-
-
Matheson, G.K.1
Guthrie, D.2
Bauer, C.3
Knowles, A.4
White, G.5
Ruston, C.6
-
23
-
-
0028240967
-
Sigma-1 and sigma-2 sites in rat brain: Comparison of regional, ontogenetic, and subcellular patterns
-
McCann, D.J., Weissman, A.D. and Su, T.P., Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patterns, Synapse, 17 (1994) 182-189.
-
(1994)
Synapse
, vol.17
, pp. 182-189
-
-
McCann, D.J.1
Weissman, A.D.2
Su, T.P.3
-
24
-
-
0027984912
-
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction
-
Ogawa, S., Okuyama, S., Araki, H. and Otomo, S., Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction, Eur. J. Pharmacol., 263 (1994) 9-15.
-
(1994)
Eur. J. Pharmacol.
, vol.263
, pp. 9-15
-
-
Ogawa, S.1
Okuyama, S.2
Araki, H.3
Otomo, S.4
-
25
-
-
0028237878
-
NE-100, a novel sigma receptor ligand: Effect on phencyclidine-induced behaviors in rats, dogs and monkeys
-
Okuyama, S., Imagawa, Y., Sakagawa, T., Nakazato, A., Yamaguchi, K., Katoh, M., Yamada, S., Araki, H. and Otomo, S., NE-100, a novel sigma receptor ligand: effect on phencyclidine-induced behaviors in rats, dogs and monkeys, Life Sci., 55 (1994) 133-138.
-
(1994)
Life Sci.
, vol.55
, pp. 133-138
-
-
Okuyama, S.1
Imagawa, Y.2
Sakagawa, T.3
Nakazato, A.4
Yamaguchi, K.5
Katoh, M.6
Yamada, S.7
Araki, H.8
Otomo, S.9
-
26
-
-
0028909879
-
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine- induced delayed cognitive dysfunction in rats
-
Okuyama, S., Ogawa, S., Nakazato, A. and Tomizawa, K., Effect of NE-100, a novel sigma receptor ligand, on phencyclidine- induced delayed cognitive dysfunction in rats, Neurosci. Lett., 189 (1995) 60-62.
-
(1995)
Neurosci. Lett.
, vol.189
, pp. 60-62
-
-
Okuyama, S.1
Ogawa, S.2
Nakazato, A.3
Tomizawa, K.4
-
27
-
-
0026339216
-
NMDA antagonists neurotoxicity: Mechanism and prevention
-
Olney, J.W., Labruyére, J., Wang, G., Wozniak, D.F., Price, M.T. and Sesma, M.A., NMDA antagonists neurotoxicity: mechanism and prevention, Science, 254 (1991) 1515-1518.
-
(1991)
Science
, vol.254
, pp. 1515-1518
-
-
Olney, J.W.1
Labruyére, J.2
Wang, G.3
Wozniak, D.F.4
Price, M.T.5
Sesma, M.A.6
-
28
-
-
0023891990
-
Expression of c-Fos protein in brain: Metabolic mapping at the cellular level
-
Sagar, S.M., Sharp, F.R. and Curran, T., Expression of c-Fos protein in brain: metabolic mapping at the cellular level, Science, 240 (1988) 1328-1331.
-
(1988)
Science
, vol.240
, pp. 1328-1331
-
-
Sagar, S.M.1
Sharp, F.R.2
Curran, T.3
-
29
-
-
0025918387
-
Behavioural and electroencephalographic interactions between haloperidol and PCP/sigma ligands in the rat
-
Sagratella, S., Scotti de Carolis, A., Pezzola, A. and Popoli, P., Behavioural and electroencephalographic interactions between haloperidol and PCP/sigma ligands in the rat, Psychopharmacology (Berlin), 105 (1991) 485-491.
-
(1991)
Psychopharmacology (Berlin)
, vol.105
, pp. 485-491
-
-
Sagratella, S.1
Scotti de Carolis, A.2
Pezzola, A.3
Popoli, P.4
-
30
-
-
0029944764
-
Effects of sigma ligands on the ability of rimcazole to inhibit PCP hsp70 induction
-
Sharp, J.W. and Williams, D.S., Effects of sigma ligands on the ability of rimcazole to inhibit PCP hsp70 induction, Brain Res. Bull., 39 (1996) 359-366.
-
(1996)
Brain Res. Bull.
, vol.39
, pp. 359-366
-
-
Sharp, J.W.1
Williams, D.S.2
-
31
-
-
0024439325
-
Receptor mechanisms in antipsy-chotic drug action: Focus on sigma receptors
-
Snyder, S.H. and Largent, B.L., Receptor mechanisms in antipsy-chotic drug action: focus on sigma receptors, Neuropsychiatry, 1 (1989) 7-15.
-
(1989)
Neuropsychiatry
, vol.1
, pp. 7-15
-
-
Snyder, S.H.1
Largent, B.L.2
-
32
-
-
0023881233
-
Phencyclidine and psychomimetic sigma opiates: Recent insights into their biochemical and physiological site of action
-
Sonders, M.S., Keana, J.F.W. and Weber, E., Phencyclidine and psychomimetic sigma opiates: recent insights into their biochemical and physiological site of action, Trends Neurosci., 11 (1988) 37-40.
-
(1988)
Trends Neurosci.
, vol.11
, pp. 37-40
-
-
Sonders, M.S.1
Keana, J.F.W.2
Weber, E.3
-
33
-
-
0028795145
-
Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines
-
Vilner, B.J., John, C.S. and Bowen, W.D., Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res., 55 (1995) 408-413.
-
(1995)
Cancer Res.
, vol.55
, pp. 408-413
-
-
Vilner, B.J.1
John, C.S.2
Bowen, W.D.3
|