Selective in vivo deletion of alloactivated TH1 cells by OKT3 monoclonal antibody in acute rejection

Immunology Letters

Volumn 57, Issue 1-3, 1997, Pages 151-153

  Reinke, P ^a   Schwinzer, H ^b   Hoflich C ^c   Ode Hakim, C ^c   Docke W D ^c   Frei, U ^a   Volk, H D ^c  

^a HUMBOLDT UNIVERSITY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Monoclonal antibody; OKT3 cells; T lymphocytes

Indexed keywords

AZATHIOPRINE; CD3 ANTIGEN; CYCLOSPORIN A; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; MESSENGER RNA; METHYLPREDNISOLONE; OKT 3; PENTOXIFYLLINE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; GRAFT REJECTION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY TRANSPLANTATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MIXED LYMPHOCYTE REACTION; MONOCYTE; OPSONIZATION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

CLONAL DELETION; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; KIDNEY TRANSPLANTATION; MUROMONAB-CD3; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; TH1 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030745107     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2478(97)00092-8     Document Type: Conference Paper

References (2)

1. L. Chatenoud, Anti-CD3 and anti-TCR monoclonal antibodies, in: J.F. Bach (Ed.), T-cell Directed Immunointervention, Black-well, Oxford, 1993, pp. 157-169.
2. S. Ode-Hakim, W.D. Döcke, F. Kern, F. Emmrich, H.D. Volk, P. Reinke, Delayed-type hypersensitivitylike mechanisms dominate late acute rejection episodes in renal allograft recipients, Transplantation 61 (1996) 1233-1240.