Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity

European Journal of Medicinal Chemistry

Volumn 32, Issue 7-8, 1997, Pages 595-605

  Dei, S ^a   Bartolini, A ^a   Bellucci, C ^a   Ghelardini, C ^a   Gualtieri, F ^a   Manetti, D ^a   Romanelli, M N ^a   Scapecchi, S ^a   Teodori, E ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Atropine derivative; Enantiomer separation; Enantioselectivity; Muscarinic antagonism; Subtype selectivity

Indexed keywords

ATROPINE DERIVATIVE; MUSCARINIC RECEPTOR; RECEPTOR SUBTYPE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENANTIOMER; GUINEA PIG; HEART ATRIUM; ILEUM; MOUSE; NONHUMAN; RABBIT; STEREOSPECIFICITY; SUBCUTANEOUS DRUG ADMINISTRATION; UTERUS; VAS DEFERENS;

EID: 0030744849     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)83285-0     Document Type: Article

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