Neutrophil secondary-granule deficiency as a hallmark of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells

Blood

Volumn 90, Issue 2, 1997, Pages 803-813

  Miyauchi, Jun ^a   Ohyashiki, Kazuma ^b   Inatomi, Yuka ^b   Toyama, Keisuke ^b  

^a NATIONAL CHILDREN S HOSPITAL   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; AGED; ANIMAL CELL; ARTICLE; CASE REPORT; CELL GRANULE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; FEMALE; HUMAN; LEUKEMIA CELL; LYMPHOCYTE DIFFERENTIATION; MALE; NEUTROPHIL; PRIORITY JOURNAL;

EID: 0030744709     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.2.803     Document Type: Article

References (38)

1. Larson RA, Kondo K, Vardiman JW, Butler AE, Colomb HM, Rowley JD: Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med 76:827, 1984
2. Borrow J, Goddard AD, Sheer D, Solomon E: Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science 24:1577, 1990
3. de Thé H, Chomienne C, Lanotte M, Degos L, Dejean A: The t(15; 17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 347:558, 1990
4. Kakizuka A, Miller WH Jr, Umesono K, Warrell RP Jr, Frankel SR, Murty VVVS, Dmitrovsky E, Evans RM: Chromosomal translocation t(15; 17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML. Cell 66:663, 1991
5. Alcalay M, Zangrilli D, Pandolfi PP, Longo L, Mencarelli A, Giacomucci A, Rocchi M, Biondi A, Rambaldi A, Coco FL, Diverio D, Donti E, Grignani F, Pelicci PG: Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor a locus. Proc Natl Acad Sci USA 88:1977, 1991
6. Grignani F, Fagioli M, Alcalay M, Longo L, Pandolfi PP, Donti E, Biondi A, LoCoco F, Grignani F, Pelicci PG: Acute promyelocytic leukmia: From genetics to treatment. Blood 83:10, 1994
7. Tsai S, Collins SJ: A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage. Proc Natl Acad Sci USA 90:7153, 1993
8. Grignani F, Ferrucci PF, Testa U, Talamo G, Fagioli M, Alcalay M, Mencarelli A, Grignani F, Peschle C, Nicoletti I, Pelicci PG: The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell 74:423, 1993
9. Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L: All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood 76:1704, 1990
10. Chomienne C, Ballerini P, Balitrand N, Daniel MT, Fenaux P, Castaigne S, Degos L: All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: Structure-function relationship. Blood 76:1710, 1990
11. Warrell RP Jr, Frankel SR, Miller WH Jr, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E: Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med 324:1385, 1991
12. Bainton DF, Ullyot JL, Farquhar MG: The development of neutrophil polymorphonuclear leukocytes in human bone marrow. J Exp Med 134:907, 1971
13. Marmont AM, Damasio E, Zucker-Franklin D: Neutrophils: Normal structure and physiology, in Zucker-Franklin D, Greaves ME, Grossi CE, Marmont AM (eds): Atlas of Blood Cells: Function and Pathology (ed 2). Philadelphia, PA, Lea & Febiger, 1988, p 160
14. Brederoo P, van-der-Meulen J, Mommaas-Kienhuis AM: Development of the granule population in neutrophil granulocytes from bone marrow. Cell Tissue Res 2324:469, 1983
15. Brederoo P, van-der-Meulen J, Daems WTH: Ultrastructural localization of peroxidase activity in developing neutrophil granulocytes from human bone marrow. Histochemistry 84:445, 1986
16. Pryzwansky KB, Breton-Gorius J: Identification of a subpopulation of primary granules in human neutrophils based upon maturation and distribution: Study by transmission electron microscopy cytochemistry and high voltage electron microscopy of whole cell preparations. Lab Invest 53:664, 1985
17. Parmley RT, Rice WG, Kinkade JM Jr, Gilbert C, Barton JC: Peroxidase-containing microgranules in human neutrophils: Physical, morphological, cytochemical, and secretory properties. Blood 70:1630, 1987
18. Bainton DF: Abnormal neutrophils in acute myelogenous leukemia: Identification of subpopulations based on analysis of azurophil and specific granules. Blood Cells 1:191, 1975
19. Bainton DF, Friedlander LM, Shohet SB: Abnormalities in granule formation in acute myelogenous leukemia. Blood 49:693, 1977
20. Dittman WA, Kramer RJ, Bainton DF: Electron microscopic and peroxidae cytochemical analysis of pink pseudo-Chediak-Higashi granules in acute myelogenous leukemia. Cancer Res 40:4473, 1980
21. Miyauchi J, Watanabe Y, Enomoto Y, Takeuchi K: Lactoferrin-deficient neutrophil polymorphonuclear leucocytes in leukaemias: A semiquantitative and ultrastructural cytochemical study. J Clin Pathol 36:1397, 1983
22. Schofield KP, Stone PCW, Stuart J: Quantitative cytochemistry of blood neutrophils in acute myeloid leukemia. Br J Haematol 54:261, 1983
23. Vyas RC, Frankel SR, Agbor P, Miller WH Jr, Warrell RP Jr, Hittelman WN: Probing the pathobiology of response to all-trans retinoic acid in acute promyelocytic leukemia: Premature chromosome condensation/fluorescence in situ hybridization analysis. Blood 87:218, 1996
24. Golomb HM, Rowley JE, Vardiman JW, Testa JR, Butler A: "Microgranular" acute promyelocytic leukemia: A distinct clinical, ultrastructural, and cytogenetic entity. Blood 55:253, 1980
25. McKenna RW, Parkin J, Bloomfield CD, Sundberg RD, Brunning RD: Acute promyelocytic leukaemia: A study of 39 cases with identification of a hyperbasophilic microgranular variant. Br J Haematol 50:201, 1982
26. Miyauchi J, Sugita K, Okui M, Taguchi N, Clark SC, Shimizu K: Differentiation induction of blast cells in two cases of childhood acute megakaryoblastic leukemia in vitro by interleukin-3 and interleukin-6: An ultrastructural and cytochemical study. J Cell Physiol 148:404, 1991
27. Tulliez M, Vernant JP, Breton-Gorius J, Imbert M, Sultan C: Pseudo-Chediak-Higashi anomaly in a case of acute myeloid leukemia: Electron microscopic studies. Blood 54:863, 1979
28. Parkin JL, Brunning RD: Unusual configrations of endoplasmic reticulum in cells of acute promyelocytic leukemia. J Natl Cancer Inst 61:341, 1978
29. Lutas EM, Zucker-Franklin D: Formation of lipid inclusions in normal human leukocytes. Blood 49:309, 1977
30. Ahearm M, Trujillo JM, Cork A, Fowler A, Hart JS: The association of nuclear blebs with aneuploidy in human acute leukemia. Cancer Res 34:2887, 1974
31. Parmley RT, Eguchi M, Spicer SS: Ultrastructural cytochemistry of complex carbohydrates in leukocyte granules. J Histochem Cytochem 27:1167, 1979
32. Parmley RT, Hurst RE, Takagi M, Spicer SS, Austin RL: Glycosaminoglycans in human neutrophils and leukemic myeloblasts: Ultrastructural, cytochemical, immunologic, and biochemical characterization. Blood 61:257, 1983
33. Rado TA, Wei X, Benz EJ Jr: Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis. Blood 70:989, 1987
34. Lübbert M, Herrmann F, Koeffler HP: Expression and regulation of myeloid-specific genes in normal and leukemic myeloid cells. Blood 77:909, 1991
35. Johnston JJ, Rintels P, Chung J, Sather J, Benz EJ Jr, Berliner N: Lactoferrin gene promoter: Structural integrity and nonexpression in HL60 cells. Blood 79:2998, 1992
36. Cramer E, Pryzwansky KB, Villeval JL, Testa U, Breton-Gorius J: Ultrastructural localization of lactoferrin and myeloperoxidase in human neutrophils by immunogold. Blood 65:423, 1985
37. Miyauchi J, Watanabe Y: Immunocytochemical localization of lactoferrin in human neutrophils: An ultrastructural and morphometrical study. Cell Tissue Res 247:249, 1987
38. Gianní M, Terao M, Zanotta S, Barbui T, Rambaldi A, Garattini E: Retinoic acid and granulocyte colony-stimulating factor synergistically induce leukocyte alkaline phosphatase in acute promyelocytic leukemia cells. Blood 83:1909, 1994