메뉴 건너뛰기




Volumn 70, Issue 1, 1997, Pages 49-54

Hexarelin, a novel GHRP-6 analog, stimulates growth hormone (GH) release in a GH-secreting rat cell line (GH1) insensitive to GH-releasing hormone

Author keywords

GH1 cells; Growth hormone; Growth hormone releasing hormone; Growth hormone releasing peptides; Hexarelin

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HEXARELIN; NEUROPEPTIDE;

EID: 0030744258     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(97)00017-7     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 0026731442 scopus 로고
    • Role of glucocorticoids in the regulation of growth hormone secretion: Mechanisms and clinical significance
    • Giustina A, Wehrenberg WB. Role of glucocorticoids in the regulation of growth hormone secretion: mechanisms and clinical significance. Trends Endocrinol Metab 1992;3:306-11.
    • (1992) Trends Endocrinol Metab , vol.3 , pp. 306-311
    • Giustina, A.1    Wehrenberg, W.B.2
  • 3
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers CY, Momany F, Reynolds GA, Hong A. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology 1984;114:1537-45.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.2    Reynolds, G.A.3    Hong, A.4
  • 5
    • 0025988605 scopus 로고
    • Growth hormone (GH) responses to the hexapeptide GH-releasing peptide and GH-releasing hormone (GHRH) in the cynomologus macaque: Evidence for non-GHRH mediated responses
    • Malozowski S, Hao EH, Ren SG, Marin G, Liu L, Southers JL, Merriam GR. Growth hormone (GH) responses to the hexapeptide GH-releasing peptide and GH-releasing hormone (GHRH) in the cynomologus macaque: evidence for non-GHRH mediated responses. J Clin Endocrinol Metab 1991;73:314-7.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 314-317
    • Malozowski, S.1    Hao, E.H.2    Ren, S.G.3    Marin, G.4    Liu, L.5    Southers, J.L.6    Merriam, G.R.7
  • 6
    • 0026647332 scopus 로고
    • Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men
    • Hartman ML, Farello G, Pezzoli SS, Thorner MO. Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men. J Clin Endocrinol Metab 1992;74:1378-84.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1378-1384
    • Hartman, M.L.1    Farello, G.2    Pezzoli, S.S.3    Thorner, M.O.4
  • 10
    • 0021368643 scopus 로고
    • Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides
    • Momany F, Bowers CY, Reynolds GA, Chang D, Hong A, Newlander K. Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides. Endocrinology 1985;114:1531-6.
    • (1985) Endocrinology , vol.114 , pp. 1531-1536
    • Momany, F.1    Bowers, C.Y.2    Reynolds, G.A.3    Chang, D.4    Hong, A.5    Newlander, K.6
  • 12
    • 0024412624 scopus 로고
    • 2 on growth hormone (GH)-releasing factor stimulated GH release and intracellular adenosine 3′,5′-monophosphate accumulation in rat primary pituitary cell culture
    • 2 on growth hormone (GH)-releasing factor stimulated GH release and intracellular adenosine 3′,5′-monophosphate accumulation in rat primary pituitary cell culture. Endocrinology 1989;124:2791-8.
    • (1989) Endocrinology , vol.124 , pp. 2791-2798
    • Cheng, K.1    Chan, W.W.S.2    Barreto, A.3    Convey, E.M.4    Smith, R.G.5
  • 17
    • 0026607276 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors
    • Goth MI, Lyons CE, Canni BJ, Thorner MO. Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology 1985;130:939-44.
    • (1985) Endocrinology , vol.130 , pp. 939-944
    • Goth, M.I.1    Lyons, C.E.2    Canni, B.J.3    Thorner, M.O.4
  • 18
    • 0025809717 scopus 로고
    • On the actions of the growth hormone-releasing hexapeptide, GHRP
    • Bowers CY, Sartor AO, Reynolds GA, Badger TM. On the actions of the growth hormone-releasing hexapeptide, GHRP. Endocrinology 1991;128:2027-35.
    • (1991) Endocrinology , vol.128 , pp. 2027-2035
    • Bowers, C.Y.1    Sartor, A.O.2    Reynolds, G.A.3    Badger, T.M.4
  • 19
    • 0025267776 scopus 로고
    • Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone
    • Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab 1990;70:975-82.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 975-982
    • Bowers, C.Y.1    Reynolds, G.A.2    Durham, D.3    Barrera, C.M.4    Pezzoli, S.S.5    Thorner, M.O.6
  • 20
    • 0028887608 scopus 로고
    • Effect of GHRP-6 and GHRH on GH secretion in rats following chronic glucocorticoid treatment
    • Voltz DM, Piering AW, Magestro M, Giustina A, Wehrenberg WB. Effect of GHRP-6 and GHRH on GH secretion in rats following chronic glucocorticoid treatment. Life Sci 1995;56:491-7.
    • (1995) Life Sci , vol.56 , pp. 491-497
    • Voltz, D.M.1    Piering, A.W.2    Magestro, M.3    Giustina, A.4    Wehrenberg, W.B.5
  • 21
    • 0024396484 scopus 로고
    • Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites
    • Codd EE, Shu AYL, Walker RF. Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites. Neuropharmacology 1989;28:1139-44.
    • (1989) Neuropharmacology , vol.28 , pp. 1139-1144
    • Codd, E.E.1    Shu, A.Y.L.2    Walker, R.F.3
  • 22
    • 0014245352 scopus 로고
    • Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone
    • Tashjian AH, Yasumura Y, Levine L, Sato GH, Parker ML. Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology 1968;82:342-8.
    • (1968) Endocrinology , vol.82 , pp. 342-348
    • Tashjian, A.H.1    Yasumura, Y.2    Levine, L.3    Sato, G.H.4    Parker, M.L.5
  • 25
    • 0018382866 scopus 로고
    • 1 cells by 3,5,3′triiodo-L-thyronine and glucocorticoid agonists and antagonists: Studies on the indipendent and synergistic regulation of the growth hormone response
    • 1 cells by 3,5,3′triiodo-L-thyronine and glucocorticoid agonists and antagonists: studies on the indipendent and synergistic regulation of the growth hormone response. Biochemistry 1979;18:715-21.
    • (1979) Biochemistry , vol.18 , pp. 715-721
    • Samuels, H.1    Stanley, F.2    Shapiro, L.E.3
  • 27
    • 0029151033 scopus 로고
    • Comparison of the effects of growth hormone-releasing hormone and hexarelin, a novel growth hormone-releasing peptide-6 analog, on growth hormone secretion in humans with or without glucocorticoid excess
    • Giustina A, Bussi AR, Deghenghi R, Imbimbo B, Licini M, Poiesi C, Wehrenberg WB. Comparison of the effects of growth hormone-releasing hormone and hexarelin, a novel growth hormone-releasing peptide-6 analog, on growth hormone secretion in humans with or without glucocorticoid excess. J Endocrinol 1995;146:227-32.
    • (1995) J Endocrinol , vol.146 , pp. 227-232
    • Giustina, A.1    Bussi, A.R.2    Deghenghi, R.3    Imbimbo, B.4    Licini, M.5    Poiesi, C.6    Wehrenberg, W.B.7
  • 28
    • 0025901021 scopus 로고
    • Demonstration and characterization of the specific binding of growth hormone-releasing peptide to rat anterior pituitary and hypothalamic membranes
    • Sethmadhavan K, Veeraragavan K, Bowers CY Demonstration and characterization of the specific binding of growth hormone-releasing peptide to rat anterior pituitary and hypothalamic membranes. Biochem Biophys Res Commun 1991;178:31-7.
    • (1991) Biochem Biophys Res Commun , vol.178 , pp. 31-37
    • Sethmadhavan, K.1    Veeraragavan, K.2    Bowers, C.Y.3
  • 29
    • 0017073654 scopus 로고
    • A possible role of cyclic AMP in mediating the effects of thyrotropin-releasing hormone on prolactin release and on prolactin and growth hormone synthesis in pituitary tumor cells in culture
    • Dannies PS, Gautvik KM, Tashjian AH. A possible role of cyclic AMP in mediating the effects of thyrotropin-releasing hormone on prolactin release and on prolactin and growth hormone synthesis in pituitary tumor cells in culture. Endocrinology 1976;98:1147-52.
    • (1976) Endocrinology , vol.98 , pp. 1147-1152
    • Dannies, P.S.1    Gautvik, K.M.2    Tashjian, A.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.